Proportional Frequency and Clinical Characteristics of Gastric, Esophageal, and Gastroesophageal Junction Cancers in a Private Medical Group in Brazil [0.03%]
巴西一家私人医疗集团胃、食管和胃食管交界处癌症的比例和临床特点
Gustavo Fernandes,Felipe D&#x;Almeida Costa,Flavia Paiva Proenca Lobo Lopes et al.
Gustavo Fernandes et al.
Background: Gastric cancer (GC) and esophageal cancer (EC) are among the most prevalent malignancies globally and are leading causes of cancer-related mortality. Gastroesophageal junction cancer (GEJC) is considered a dis...
Survival Analysis and Treatment Strategies for Locally Advanced Lung Squamous Cell Carcinoma in Elderly Patients [0.03%]
老年患者局部晚期肺鳞癌的生存分析及治疗策略研究
Zhong Fei Jia,Xian Zhe Zhao,Jing Chen Huo et al.
Zhong Fei Jia et al.
Background: The aim of the study was to analyze the survival and treatment strategies of elderly patients with locally advanced lung squamous cell carcinoma. ...
Organ-Specific Clinicopathological Features That Are Associated With Post-Relapse Survival of Metastatic Breast Cancer in Japanese Women: A Multicenter Cohort Study [0.03%]
日本女性复发转移性乳腺癌的器官特异性临床病理特征与预后的关系：一项多中心队列研究
Yoichi Koyama,Yoshiya Horimoto,Akimitsu Yamada et al.
Yoichi Koyama et al.
Background: Metastatic breast cancer (MBC) presents heterogeneous clinical behavior depending on the metastatic site and molecular subtype. However, only a few studies have directly compared prognostic outcomes by the org...
LINC01121 Is Associated With Prognosis and Facilitates the Proliferation, Migration, and Invasion of Colorectal Cancer [0.03%]
长链非编码RNA LINC01121与结直肠癌预后及促进增殖、迁移和侵袭的关系研究
Jiang Liu,Ying Xuan Zhang,Yin Cai et al.
Jiang Liu et al.
Background: The role of LINC01121 in the pathogenesis and prognosis of colorectal cancer (CRC) remains unknown. This study aimed to explore the function of LINC01121 in CRC development. ...
Clinical Significance and Potential Molecular Mechanisms of Angiotensin-Converting Enzyme 2 in Colorectal Cancer [0.03%]
血管紧张素转换酶2在结直肠癌的临床意义及潜在分子机制
Da Tong Zeng,Li Yang,Jia Ying Wen et al.
Da Tong Zeng et al.
Background: Angiotensin-converting enzyme 2 (ACE2) exhibits tumor-suppressive potential in cancers, but its role in colorectal cancer (CRC) is unclear. The aim of the study was to investigate ACE2 expression, clinical sig...
A Comparison of Five-Year Survival Rates Between Thermal Ablation and Hepatic Resection for Colorectal Cancer Metastasis to the Liver: A Systematic Review and Meta-Analysis [0.03%]
热消融与肝切除治疗结直肠癌肝转移5年生存率的系统评价和meta分析
Abdulrahman Alotaibi,Ghala Alshamrani,Hosam Alzobaidi et al.
Abdulrahman Alotaibi et al.
Background: A significant proportion of colorectal liver metastases (CRLMs) are unresectable. This study compares liver resection with thermal ablation. M...
Neurotoxicity of Immunotherapy: Immune Checkpoint Inhibitor-Related Encephalitis vs. Immune Effector Cell-Associated Neurotoxicity Syndrome [0.03%]
免疫治疗的神经毒性：免疫检查点抑制剂相关脑炎与效应细胞相关性神经系统毒性的区别
Takumi Sato,Kohei Chida,Shipra Gandhi et al.
Takumi Sato et al.
Immune checkpoint inhibitors and engineered T-cell therapies such as chimeric antigen receptor T-cell (CAR-T) cells and bispecific T-cell engagers (BiTEs) have revolutionized oncology care, and with them came two neurologic syndromes that l...
E2F5 Overexpression in Laryngeal Squamous Cell Carcinoma: Associations With Neutrophil Extracellular Traps in the Tumor Microenvironment [0.03%]
人喉鳞癌中E2F5过表达与肿瘤微环境中中性粒细胞胞外诱捕网的关系研究
Ke Jun Wu,Feng Zhao,Yu Feng Li et al.
Ke Jun Wu et al.
Background: Laryngeal squamous cell carcinoma (LSCC) is a common malignant tumor of the head and neck, associated with smoking and excessive alcohol consumption. The objective was to investigate the expression pattern of ...
High CDCP1 Expression Reflects Immune and Stromal Remodeling and Oncogenic Signaling in Pancreatic Ductal Adenocarcinoma [0.03%]
高CDCP1表达反映了胰腺导管腺癌中的免疫和基质重塑及致癌信号转导
Kentaro Miyake,Masanori Oshi,Akira Takenouchi et al.
Kentaro Miyake et al.
Background: CUB domain-containing protein 1 (CDCP1) is implicated in pancreatic ductal adenocarcinoma (PDAC) prognosis, but its relationship to the tumor microenvironment (TME) and oncogenic signaling remains incompletely...
Screening, Risk Reduction Strategies, and Clinical Management of Unaffected Carriers of BRCA1 or BRCA2 Pathogenic Variants [0.03%]
BRCA1/BRCA2基因致病性变异无症状携带者的筛查、风险降低策略和临床管理
Hikmat Abdel-Razeq,Razan Mansour
Hikmat Abdel-Razeq
Breast cancer remains the most common cancer globally, with approximately 5-15% of cases linked to pathogenic variants primarily in BRCA1 or BRCA2. These mutations greatly increase cancer risks, highlighting the critical need for more effec...