Targeting the Phosphoinositide 3-Kinase/Protein Kinase B Pathway Suppresses Y-Box Binding Protein 1 Expression and Inhibits Colorectal Cancer Progression [0.03%]
靶向磷脂酰肌醇-3-激酶/蛋白激酶B通路可抑制Y框蛋白1表达并抑制结直肠癌进展
Hui Shan,Yan Wang,Siyu Hu et al.
Hui Shan et al.
Background: Colorectal cancer (CRC) is one of the most prevalent and lethal malignancies worldwide, often characterized by the aberrant activation of multiple signaling pathways. Y-box binding protein 1 (YBX1), a multifun...
Liquid Plasma Induces Necroptosis Without Inflammatory Responses in Head and Neck Cancer Cells [0.03%]
液体等离子体可在头颈部癌细胞中诱导无炎症反应的坏死性凋亡
Jae Hoon Choi,Sungryeal Kim,Yun Sang Lee et al.
Jae Hoon Choi et al.
Background: Several types of regulated cell deaths are known, including apoptosis, necroptosis, autophagy, ferroptosis, and pyroptosis. Among these types of cell deaths, apoptosis is induced by many cancer therapeutic age...
IgM Myeloma: A Comprehensive Overview and Practical Approach to Chemotherapeutic Management [0.03%]
IgM型多发性骨髓瘤的全面概述和化疗管理的实际方法
Hadeel Elwaheidi,Alaa Hamad,Farah Salameh et al.
Hadeel Elwaheidi et al.
IgM myeloma is a rare subtype of multiple myeloma (MM) comprising 0.5% of all of its cases. It is characterized by the unregulated proliferation of IgM-secreting plasma cells in the bone marrow. The underlying pathogenesis involves dysregul...
Association of Low Educational Attainment and Higher Colorectal Cancer Risk: Mediatory Effect of Lifestyle-Associated Factors Within Local Context [0.03%]
低教育程度与大肠癌发病风险较高相关：本土范围内生活方式相关因素的中介作用研究
Herindita Puspitaningtyas,Juan Adrian Wiranata,Bayu Satria Wiratama et al.
Herindita Puspitaningtyas et al.
Background: Educational attainment may influence colorectal cancer (CRC) risks, though the association remains inconclusive. The association might be mediated by health behaviors. This study aimed to explore the associati...
Breast Cancer With Airway Edema Caused by Metastatic Fracture of the Cervical Vertebra [0.03%]
由颈椎转移性骨折所致支气管水肿的乳腺癌患者
Daigo Suzuki,Masanori Oshi,Aya Nishikawa et al.
Daigo Suzuki et al.
Bone is a common site of breast cancer metastasis, with the spine showing a particularly high affinity. An 83-year-old Japanese woman with Alzheimer's disease presented with a palpable mass in her left breast. A needle biopsy revealed invas...
Clinicopathological Features of HER2 Expressing Lobular Carcinoma of Breast [0.03%]
乳腺HER2阳性小叶癌的临床病理特征
Majd Khader,Bayan Maraqa,Hikmat Abdel-Razeq et al.
Majd Khader et al.
Background: Invasive lobular carcinoma (ILC) accounts for approximately 10% of invasive breast carcinomas and is the most common special subtype. Most ILCs express estrogen receptors (ERs) and progesterone receptors (PRs)...
Development and Validation of KN-DIOC: A Novel Preoperative Diagnostic Index Using Ultrasound, Complete Blood Count, and Cancer Antigen 125 for Ovarian Cancer [0.03%]
KN-DIOC的建立和验证：一种用于卵巢癌术前诊断的新指标，采用超声、血常规及CA125检测结果构建而成
Sorawit Tongyib,Teerapol Saleewong,Woraphot Chaowawanit
Sorawit Tongyib
Background: Ovarian cancer, particularly epithelial ovarian cancer (EOC), is one of the deadliest gynecological malignancies due to nonspecific early symptoms and late diagnosis. Current diagnostic tools, while useful, of...
Efficacy of Infliximab Versus Vedolizumab in the Management of Immune Checkpoint Inhibitor-Induced Colitis: A Systematic Review and Meta-Analysis [0.03%]
抗炎检查点抑制剂诱导结肠炎治疗中英夫利昔单抗和维多珠单抗疗效的系统评价和 meta 分析
Shreya Shambhavi,Harmanjeet Singh,Ganesh Ramaprasad et al.
Shreya Shambhavi et al.
Background: Immune checkpoint inhibitors (ICIs) can cause severe gastrointestinal immune-related adverse events (irAEs), often leading to treatment interruption and increased morbidity. Immune-mediated colitis (IMC) range...
Metabolic Reprogramming-Related Genes in Lung Adenocarcinoma: Identification and Prognostic Model Construction [0.03%]
肺癌腺癌代谢重组相关基因的识别与预后模型构建
Ling Zhi Lian,Fang Huang,Jia Lang et al.
Ling Zhi Lian et al.
Background: Lung adenocarcinoma (LUAD), the predominant histological subtype of lung cancer, persists in presenting a dismally low 5-year overall survival (OS) rate, notwithstanding advancements in treatment modalities. T...
Mechanism of Action of Resveratrol Affecting the Biological Function of Breast Cancer Through the Glycolytic Pathway [0.03%]
白藜通过糖酵解途径影响乳腺癌生物学功能的作用机制研究
Yu Gao,Yao Yao Wang,Bao Di Wang et al.
Yu Gao et al.
Background: Phosphoglycerate kinase 1 (PGK1) plays a crucial role in the glycolytic pathway and its overexpression has a negative impact on tumor development and prognosis. Resveratrol, a natural polyphenolic compound, ha...