Akane Onogi,Daichi Kodama,Naoki Watanabe et al.
Akane Onogi et al.
Malignant melanoma (MM) is a tumor that usually occurs in the skin, but this malignant tumor can also develop in extracutaneous tissues, including urogenital tissues. In regard to MM occurring in urogenital tissues, bladder origin is common...
Case Reports
World journal of oncology. 2024 Oct;15(5):837-843. DOI:10.14740/wjon1899 2024
Chelsey C Ciambella,Kazuaki Takabe
Chelsey C Ciambella
Breast cancer is one of the most common malignancies, affecting millions of people worldwide annually. The treatment paradigm for early-stage breast cancer is in flux. The focus is now on opportunities to de-escalation treatment to minimize...
Prognostic Implications of Timing of Immunotherapy in Stage IV Non-Small Cell Lung Cancer [0.03%]
免疫治疗时机对四期非小细胞肺癌的预后影响
Jorge Raul Vazquez-Urrutia,Max Greenberg,Junjia Zhu et al.
Jorge Raul Vazquez-Urrutia et al.
Background: Currently, the established approach for addressing stage IV non-small cell lung cancer (NSCLC) involves combining chemotherapy with immunotherapy. However, the necessity for molecular analysis prior to commenc...
Multi-Gene Panel Testing for Hereditary Cancer Predisposition Among Patients Sixty-Five Years and Above Diagnosed With Breast Cancer [0.03%]
老年乳腺癌患者遗传性癌症易感性的多基因检测Panelling检测研究
Hikmat Abdel-Razeq,Faris Tamimi,Baha Sharaf et al.
Hikmat Abdel-Razeq et al.
Background: The availability and affordability of germline genetic testing (GGT) has resulted in a broader utilization in daily clinical practice. However, adherence to testing guidelines is low, especially among older pa...
SNX4 Is Correlated With Immune Infiltration and Prognosis in Clear Cell Renal Cell Carcinoma [0.03%]
SNX4与透明细胞肾细胞癌免疫浸润和预后相关性研究
Yu Meng Chai,Zhong Bao Zhou,Run Ze Liu et al.
Yu Meng Chai et al.
Background: Clear cell renal cell carcinoma (ccRCC) is known as the most common and malignant histologic subtype of renal carcinoma. Sorting nexin 4 (SNX4) plays a regulatory role in recycling from endosomes to the plasma...
Secondary Hemophagocytic Lymphohistiocytosis Following Dostarlimab Treatment in a Patient With Metastatic Endometrial Cancer [0.03%]
接受Dostarlimab治疗后继发第二次噬血细胞综合征的子宫内膜癌患者案例报告
Emilie Rollet,Sebastien Puigrenier,Abeer Najem et al.
Emilie Rollet et al.
Immunotherapy is a rapidly expanding cancer treatment strategy. Dostarlimab is administered as the first-line treatment for metastatic endometrial cancer in combination with chemotherapy. Herein, we describe the case of a 72-year-old female...
Case Reports
World journal of oncology. 2024 Oct;15(5):844-850. DOI:10.14740/wjon1917 2024
Targeting SNAI1-Mediated Colorectal Cancer Chemoresistance and Stemness by Sphingosine Kinase 2 Inhibition [0.03%]
通过抑制鞘氨醇激酶2靶向SNAI1介导的结直肠癌化疗耐药和干细胞特性
Harinarayanan Janakiraman,Zachary Gao,Yun Zhu et al.
Harinarayanan Janakiraman et al.
Background: Epithelial-to-mesenchymal transition (EMT), cancer stem cells (CSCs), and colorectal cancer (CRC) therapy resistance are closely associated. Prior reports have demonstrated that sphingosine-1-phosphate (S1P) s...
On the Origin of Abdominal Venous Leiomyosarcomas: The Role of the Sex-Hormone Drainage Pathways [0.03%]
腹腔内血管平滑肌肉瘤的起源：性激素回流通道的作用
Usman Tarique,David P Cyr,Carlo Morosi et al.
Usman Tarique et al.
Background: We hypothesized that abdominal venous leiomyosarcoma (AV-LMS) disproportionately originates in veins of the sex-hormone drainage pathway (SHDP). Our purpose was to classify the anatomical origin of AV-LMS in a...
Assessment of Five-Year Relative Survival of Patients With Endometrial Cancer: A Period Analysis [0.03%]
子宫内膜癌患者五年相对生存率的评估：一段时期的分析
Xiao Jiao Zhao,Xin Bing,Qi Qi Lei et al.
Xiao Jiao Zhao et al.
Background: Endometrial cancer is one of the most common female cancers globally and in China. Although timely assessment of 5-year relative survival is crucial for guiding secondary prevention and early screening program...
Increased Vitamin C Intake Is Associated With Decreased Pancreatic Cancer Risk [0.03%]
维生素C摄入增加与胰腺癌发病风险降低有关
Maria Pereira,Matthew Cardeiro,Lexi Frankel et al.
Maria Pereira et al.
Background: Patients with pancreatic cancer have an unfavorable 5-year survival rate of approximately 3% due to diagnosis occurring at advanced stages. Prior research has proposed vitamin C may have a therapeutic and prev...