Multi-Gene Panel Testing for Hereditary Cancer Predisposition Among Patients Sixty-Five Years and Above Diagnosed With Breast Cancer [0.03%]
老年乳腺癌患者遗传性癌症易感性的多基因检测Panelling检测研究
Hikmat Abdel-Razeq,Faris Tamimi,Baha Sharaf et al.
Hikmat Abdel-Razeq et al.
Background: The availability and affordability of germline genetic testing (GGT) has resulted in a broader utilization in daily clinical practice. However, adherence to testing guidelines is low, especially among older pa...
SNX4 Is Correlated With Immune Infiltration and Prognosis in Clear Cell Renal Cell Carcinoma [0.03%]
SNX4与透明细胞肾细胞癌免疫浸润和预后相关性研究
Yu Meng Chai,Zhong Bao Zhou,Run Ze Liu et al.
Yu Meng Chai et al.
Background: Clear cell renal cell carcinoma (ccRCC) is known as the most common and malignant histologic subtype of renal carcinoma. Sorting nexin 4 (SNX4) plays a regulatory role in recycling from endosomes to the plasma...
Secondary Hemophagocytic Lymphohistiocytosis Following Dostarlimab Treatment in a Patient With Metastatic Endometrial Cancer [0.03%]
接受Dostarlimab治疗后继发第二次噬血细胞综合征的子宫内膜癌患者案例报告
Emilie Rollet,Sebastien Puigrenier,Abeer Najem et al.
Emilie Rollet et al.
Immunotherapy is a rapidly expanding cancer treatment strategy. Dostarlimab is administered as the first-line treatment for metastatic endometrial cancer in combination with chemotherapy. Herein, we describe the case of a 72-year-old female...
Case Reports
World journal of oncology. 2024 Oct;15(5):844-850. DOI:10.14740/wjon1917 2024
Targeting SNAI1-Mediated Colorectal Cancer Chemoresistance and Stemness by Sphingosine Kinase 2 Inhibition [0.03%]
通过抑制鞘氨醇激酶2靶向SNAI1介导的结直肠癌化疗耐药和干细胞特性
Harinarayanan Janakiraman,Zachary Gao,Yun Zhu et al.
Harinarayanan Janakiraman et al.
Background: Epithelial-to-mesenchymal transition (EMT), cancer stem cells (CSCs), and colorectal cancer (CRC) therapy resistance are closely associated. Prior reports have demonstrated that sphingosine-1-phosphate (S1P) s...
On the Origin of Abdominal Venous Leiomyosarcomas: The Role of the Sex-Hormone Drainage Pathways [0.03%]
腹腔内血管平滑肌肉瘤的起源：性激素回流通道的作用
Usman Tarique,David P Cyr,Carlo Morosi et al.
Usman Tarique et al.
Background: We hypothesized that abdominal venous leiomyosarcoma (AV-LMS) disproportionately originates in veins of the sex-hormone drainage pathway (SHDP). Our purpose was to classify the anatomical origin of AV-LMS in a...
Assessment of Five-Year Relative Survival of Patients With Endometrial Cancer: A Period Analysis [0.03%]
子宫内膜癌患者五年相对生存率的评估：一段时期的分析
Xiao Jiao Zhao,Xin Bing,Qi Qi Lei et al.
Xiao Jiao Zhao et al.
Background: Endometrial cancer is one of the most common female cancers globally and in China. Although timely assessment of 5-year relative survival is crucial for guiding secondary prevention and early screening program...
Increased Vitamin C Intake Is Associated With Decreased Pancreatic Cancer Risk [0.03%]
维生素C摄入增加与胰腺癌发病风险降低有关
Maria Pereira,Matthew Cardeiro,Lexi Frankel et al.
Maria Pereira et al.
Background: Patients with pancreatic cancer have an unfavorable 5-year survival rate of approximately 3% due to diagnosis occurring at advanced stages. Prior research has proposed vitamin C may have a therapeutic and prev...
Use of Period Analysis to Timely Assess Five-Year Relative Survival for the Patients With Bone Cancer [0.03%]
利用周期分析及时评估骨癌患者五年相对生存率
Xian Kuan Xie,Xiao Jiao Zhao,Run Hua Li et al.
Xian Kuan Xie et al.
Background: While timely assessment of long-term survival for patients with bone cancer is essential for evaluation on early detection and prognosis level of treatment of bone cancer, those data are extremely scarce in Ch...
A New Ferroptosis-Related Long Non-Coding RNA Risk Model Predicts the Prognosis of Patients With Papillary Thyroid Cancer [0.03%]
一种新的铁死亡相关长链非编码RNA风险模型可预测乳头状甲状腺癌患者的预后
Jun Yu Zhao,Jin Ming Yao,Xin Zhong Zhang et al.
Jun Yu Zhao et al.
Background: Ferroptosis is a novel form of regulated cell death that involves in cancer progression. However, the role of ferroptosis-related long non-coding RNAs (lncRNAs) in papillary thyroid cancer (PTC) remains to be ...
Significance and Possible Biological Mechanism for CLDN8 Downregulation in Kidney Renal Clear Cell Carcinoma Tissues [0.03%]
CLDN8低表达在肾透明细胞癌组织中的意义及可能的生物学机制研究
Han Chu Ji,Jian Di Li,Guan Lan Zhang et al.
Han Chu Ji et al.
Background: The clinical role of claudin 8 (CLDN8) in kidney renal clear cell carcinoma (KIRC) remains unclarified. Herein, the expression level and potential molecular mechanisms of CLDN8 underlying KIRC were determined....