The Impact of Chronic Kidney Disease on In-Hospital Outcomes in Patients With Acute Respiratory Distress Syndrome [0.03%]
慢性肾脏病对急性呼吸窘迫综合征患者住院期间预后的影响
Adishwar Rao,Ayesha Anwar,Akriti Agrawal et al.
Adishwar Rao et al.
Background: Acute respiratory distress syndrome (ARDS) is associated with high mortality rates in critically ill patients. Renopulmonary interplay remains crucial in contributing to the outcomes in patients with ARDS. Whi...
Integrated Mendelian Randomization and Single-Cell RNA Sequencing Analyses Reveal Lactate Metabolism as a Key Pathway in COVID-19-Induced Pulmonary Fibrosis [0.03%]
整合孟德尔随机化和单细胞RNA测序分析揭示乳酸代谢在COVID-19诱导的肺纤维化中的关键作用
Xin Zhang,Liping Jia,Tuersun Yeziya et al.
Xin Zhang et al.
Background: The COVID-19 pandemic has led to a variety of long-term complications, with COVID-19-induced idiopathic pulmonary fibrosis (IPF) becoming a major concern. However, the underlying mechanisms, effective therapeu...
TAPI-1 Combined With Silicone Stents Alleviated Severe Traumatic Tracheal Stenosis via the ADAM17/TGF-β1 Pathway [0.03%]
TAPI-1联合硅酮支架通过ADAM17/TGF-β1信号通路缓解重度创伤性气管狭窄
Zehua Yang,Lan Pan,Tian Xie et al.
Zehua Yang et al.
Background: Traumatic tracheal stenosis is characterized by airway granular proliferation after trauma, which may lead to asphyxy. Abnormal activation of the ADAM17/TGF-β1 pathway may trigger excessive repair and airway ...
Efficacy and Safety of Pirfenidone for Mitigation of Interstitial Lung Abnormalities in COVID-19 Patients: A Meta-Analysis [0.03%]
吡非尼酮用于减轻COVID-19患者间质性肺病变的有效性和安全性：一项荟萃分析
Ziyi Zhang,Xiang Fang,Jinhui Gao et al.
Ziyi Zhang et al.
Background: Although post-COVID-19 interstitial lung abnormalities (ILAs) are common, the use of antifibrotic agents to prevent their onset and progression is controversial. We aimed to investigate the effectiveness and s...
Assessing the Impact of Colchicine on Pulmonary Fibrosis Using Imaging in Patients With Moderate-to-Severe COVID-19 Pneumonia [0.03%]
评估秋水仙碱对中重度COVID-19肺炎患者肺纤维化影响的影像学研究
Gulhan Ayhan Albayrak,Mustafa Ilteris Bardakci,Ugur Temel
Gulhan Ayhan Albayrak
Objective: Pulmonary fibrosis may develop in patients with severe clinical conditions, especially those with high inflammatory indicators. We aimed to investigate the 15-month follow-up clinical outcomes in patients with ...
Systemic Inflammatory Response Index Has a Value for the Early Diagnosis and Short-Term Prognostic Assessment of Severe Pneumonia in the Elderly [0.03%]
全身性炎性反应指数有助于老年重症肺炎的早期诊断及短期预后评估
Xiao Xu,Huajuan Xu,Ming Li et al.
Xiao Xu et al.
This article probed the value of systemic inflammatory response index (SIRI) in the early diagnosis and short-term prognostic assessment of severe pneumonia (SPM) in the elderly. First, 266 elderly patients with pneumonia were retrospective...
Oroxylin A From Scutellaria baicalensis Improved Pulmonary Fibrosis of Radiation Pneumonia Through Ferroptosis by Nrf2 [0.03%]
由Baikal skullcap中的Oroxylin A通过Nrf2调节的铁死亡改善放射性肺纤维化
Wei Zhang,Wen Hao,Xiaoxia Gao et al.
Wei Zhang et al.
Radiation pneumonitis can result in respiratory dysfunction and progress to radiation fibrosis, and in severe cases, respiratory failure may occur. Hence, we investigated the effects of Oroxylin A from Scutellaria baicalensis in radiation p...
Gastroesophageal Reflux, Sleep-Disordered Breathing, and Outcomes in Patients With Idiopathic Pulmonary Fibrosis [0.03%]
胃食管反流、睡眠呼吸障碍与特发性肺纤维化患者的预后关系研究
Braden Ellis,Daniel Morris,Andrea Peterson et al.
Braden Ellis et al.
Background: Gastroesophageal reflux disease (GERD) and obstructive sleep apnea (OSA) may negatively impact idiopathic pulmonary fibrosis (IPF), but data on their concurrent contributions are lacking. We aimed to test the ...
Upregulation of TFDP1 and CDC27 Plays an Important Role in Bronchiectasis [0.03%]
TFDP1和CDC27的上调在支气管扩张发病机制中起重要作用
Kang-Kang Hong,Guo-Sheng Li,Rong-Quan He et al.
Kang-Kang Hong et al.
Background: Noncystic fibrosis (non-CF) bronchiectasis is a chronic respiratory disease characterized by irreversible bronchial dilation, with an increasing global prevalence and substantial clinical burden. Despite the a...
Characteristics and Impact of Peripheral and Respiratory Muscle Weakness in Patients With Interstitial Lung Disease: A Cross-Sectional Observational Study [0.03%]
间质性肺疾病患者外周肌肉和呼吸肌无力的特征及其影响：横断面观察性研究
Jinliang Meng,Lun Zhang,Rui Xu et al.
Jinliang Meng et al.
Background: Muscle weakness is a clinically significant complication of interstitial lung disease (ILD) that worsens dyspnea, fatigue, and quality of life, but its epidemiology and clinical impact remain understudied. ...
Observational Study
Canadian respiratory journal. 2025 Dec 12:2025:7069021. DOI:10.1155/carj/7069021 2025