HO-1-Enriched Lung-Derived Exosomes Mediate Cognitive Impairment in a Mice Model of COPD Exacerbation [0.03%]
富HO-1小鼠急性加重肺源性外泌体诱导的认知功能障碍及其机制研究
Guang Yu Yin,Jia Qiang Zhang,Zhou Ling Xie et al.
Guang Yu Yin et al.
Objective: This study aimed to elucidate the impact of HO-1 on cognitive function in chronic obstructive pulmonary disease (COPD) exacerbation mice and uncover the bridging role of exosomes in the interorgan transport of ...
Fezakinumab Alleviates Cigarette Smoke-Induced COPD by Suppressing the JAK1/STAT3 Pathway in Mice [0.03%]
费扎钦单抗通过抑制JAK1/STAT3信号通路缓解小鼠支气管炎引起的慢阻肺症状
Yuwei Wang,Li Jin,Erche Yang et al.
Yuwei Wang et al.
Background: Elevated Th-22 cells and IL-22 are linked to chronic obstructive pulmonary disease (COPD); however, their mechanisms are not fully elucidated. This study aimed to evaluate the therapeutic effects of AG490 and ...
Mediating Role of BMI in the Association Between Obstructive Sleep Apnea and Nonalcoholic Fatty Liver Disease: A Cross-Sectional Mediation Analysis [0.03%]
BMI在阻塞型睡眠呼吸暂停与非酒精性脂肪肝疾病关联中的中介作用：横断面中介分析
Zhende Luo,Lan Shu,Wei Yu
Zhende Luo
Objective: To investigate the mediating role of body mass index (BMI) in the association between obstructive sleep apnea (OSA) and nonalcoholic fatty liver disease (NAFLD). ...
Relationship Between Thoracic CT Severity Score and Scadding Staging With PFT, DLCO, and 6MWT in Patients With Sarcoidosis [0.03%]
胸部CT严重程度评分与Sarcoidosis患者的Scadding分期肺功能、弥散量和6分钟步行试验的关系研究
Muhammet Ali Takeş,Celalettin Korkmaz,Necdet Poyraz et al.
Muhammet Ali Takeş et al.
Background: Chest computed tomography (CT) is widely used in the diagnosis and follow-up of diffuse parenchymal lung diseases like sarcoidosis. This study investigated the relationship between the Thoracic CT Severity Sco...
Cytokine Expression Profiling in Idiopathic Pulmonary Fibrosis: Insights From Integrative Proteomic Analysis [0.03%]
整合蛋白质组学分析在特发性肺纤维化细胞因子表达谱中的应用及新发现
Chenyou Shen,Wei Wang,Guirong Li et al.
Chenyou Shen et al.
Introduction: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic lung disease with a poor prognosis and no effective pharmacological treatments. Cytokines are a class of small-molecule proteins with div...
Association of Hematocrit and Albumin Difference With Ventilator-Associated Pneumonia in Patients With Continuous Mechanical Ventilation: Evidence From MIMIC-IV Database [0.03%]
血细胞比容与白蛋白差值与长期机械通气患者的呼吸机相关性肺炎的相关性：来自MIMIC-IV数据库的证据
Weiwei Mao,Chengyun Mu
Weiwei Mao
Objective: This study aims to investigate the relationship between the difference in hematocrit and albumin (HCT-ALB) and ventilator-associated pneumonia (VAP) among patients undergoing continuous mechanical ventilation. ...
Impact of Comorbidities on Treatments and Outcomes of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension [0.03%]
共病对系统性硬化症相关肺动脉高压治疗和结局的影响
Lisa Lim,Dylan Hansen,Jessica Fairley et al.
Lisa Lim et al.
Aim: Treatment recommendations for systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) have evolved from initial monotherapy to upfront combination therapy with agents, including endothelin receptor an...
LINC01214 Promotes Non-Small Cell Lung Cancer Through the miR-497-3p/HSP90AB1 Axis [0.03%]
长链非编码RNA LINC01214通过miR-497-3p/HSP90AB1轴促进非小细胞肺癌进展
Guangfu Xu,Ling Zhang,Fei Li et al.
Guangfu Xu et al.
Objective: This study aimed to explore the potential of LINC01214 in providing prognostic and therapeutic insights, thereby offering valuable references for the research of non-small cell lung cancer (NSCLC). ...
Thoracic CT Screening in a Population With Unidentified Lung Cancer Risk Factors: Does It Facilitate the Early Diagnosis of Lung Cancer? [0.03%]
在肺癌危险因素未知的群体中进行胸部CT筛查能否促进肺癌的早期诊断？
Aysegul Gencer,Buket Caliskaner Ozturk,Gizem Senkardesler et al.
Aysegul Gencer et al.
Background: Lung cancer is the predominant cause of cancer-related mortality globally. Computed tomography (CT) scanning is employed to enhance the early diagnosis of lung cancer by screening for risk factors. This study ...
The Diagnostic Value of Transthoracic Echocardiography Parameters Under the New Diagnostic Criteria for Pulmonary Hypertension [0.03%]
新肺动脉高压诊断标准下的经胸超声心动图参数的诊断价值分析
Yuankun Qi,Junjun Liu,Xiaopei Cui et al.
Yuankun Qi et al.
Background: In 2022, new guidelines for the diagnosis and treatment of pulmonary hypertension (PH) revised the hemodynamic definition, reducing the mean pulmonary artery pressure threshold from ≥ 25 to > 20 mmHg. The opt...