Synergistic Effects of Erythromycin and Budesonide on the Mitigation of Tracheal Stenosis Associated With Macrophage Phenotype Alteration and HDAC2 Upregulation [0.03%]
erythromycin和budesonide在调节巨噬细胞表型和提高HDAC2表达水平对气管狭窄的协同治疗作用研究
Jinghua Gan,Guangnan Liu
Jinghua Gan
Objective: We investigated the therapeutic effects of combined erythromycin and budesonide treatment on tracheal stenosis (TS) and the associated changes in macrophage-related markers and HDAC2 expression. ...
Emerging Trends and Research Frontiers in Climate Change and Asthma: Insights From a Two-Decade Bibliometric Analysis [0.03%]
气候变化与哮喘研究的现状和前沿：基于20年文献数据的计量学分析
Yixin Wang,Huanxia Qu,Xinchen Shu et al.
Yixin Wang et al.
Background: Climate change has emerged as a major public health challenge, with significant implications for respiratory diseases such as asthma. Environmental factors, including air pollution, aeroallergens, and extreme ...
A Prospective, Multicenter Study Investigating the Effectiveness of an Oscillating Positive Expiratory Pressure (OPEP) Device in COPD Patients in Québec, Canada [0.03%]
加拿大魁北克多中心前瞻性研究调查震荡式气道廓清仪(OPEP)在慢性阻塞性肺疾病患者中疗效的影响研究
Claude Poirier,Pierre-Alexandre Ménard,Romina Tate Gemelli et al.
Claude Poirier et al.
Rationale: Clinical benefits of oscillating positive expiratory pressure (OPEP) devices have been previously demonstrated in many respiratory diseases, including chronic obstructive pulmonary disease (COPD). This study ai...
Multicenter Study
Canadian respiratory journal. 2026;2026(1):e2033683. DOI:10.1155/carj/2033683 2026
DLGAP5 Drives Lung Adenocarcinoma Cell Growth by Promoting Autophagy Activity [0.03%]
DLGAP5通过促进自噬活性驱动肺腺癌细胞增殖
Shuying You,Xiangbo Zeng,Na Li et al.
Shuying You et al.
Background: Autophagy is reported to participate in tumorigenesis and plays a vital role in tumor cell survival. Here, we aimed to elucidate the regulatory mechanism between discs large homolog-associated protein 5 (DLGAP...
Effect and Safety of Bronchoscopy Based on Imaging Evaluation in Patients With Acute Exacerbation of Bronchiectasis [0.03%]
基于影像学评估的支气管镜在支气管扩张急性加重患者中的疗效及安全性分析
Biliang Li,Zeng Juan,Mingfeng Wang et al.
Biliang Li et al.
Objective: To evaluate the efficacy and safety of imaging-assisted bronchoscopic interventions in acute bronchiectasis exacerbations and analyze their effects on pulmonary function, inflammation, and quality of life for e...
Correlation Analysis Between Immune Status and Bronchoscopic Airway Findings in Various Ages of SMPP Children [0.03%]
不同年龄段SMPP儿童免疫状态与支气管镜下气道表现相关性分析
Peng Li,Ruiyang Sun,Jiapu Hou et al.
Peng Li et al.
Objective: To investigate the correlation between trends in immune markers and airway mucosal changes in SMPP by controlling for age. Study design: ...
Shared Genetic Susceptibility Between Asthma and Immune-Mediated Inflammatory Diseases [0.03%]
哮喘和免疫介导性炎症性疾病之间的共有遗传易感性
Liping Zhou,Kai Sun
Liping Zhou
Background: Existing studies lack comprehensive evaluations of the genetic relationships between asthma and a broader spectrum of immune-mediated inflammatory diseases (IMIDs). This study aims to elucidate the genetic cor...
Computed Tomography-Based Evaluation of Airway Remodeling for Distinguishing Asthma-Chronic Obstructive Pulmonary Disease Overlap From Asthma and Chronic Obstructive Pulmonary Disease [0.03%]
基于CT的气道重塑评估用于区分哮喘-慢性阻塞性肺病重叠与单纯性哮喘和慢性阻塞性肺病
Mei-Cheng Chen,Yang-Li Liu,Feng-Jia Chen et al.
Mei-Cheng Chen et al.
Objectives: We aimed to explore the practicality of CT imaging for diagnosing asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACO). ...
Multiomics Approach Identifies Novel Genetic Determinants and Therapeutic Targets for Asthma [0.03%]
多组学方法识别出新的遗传决定因素和哮喘治疗靶点
Fang Liu,Hongtao Cui,Yan Mei et al.
Fang Liu et al.
Asthma constitutes a widespread chronic respiratory disease with multifactorial origins, in which definitive genetic components remain incompletely understood. This investigation synthesized transcriptomic data and Mendelian randomization (...
Quantitative CT Patterns and Functional Loss Related to Welding Fume Exposure, While Handling the Confounding Effect of Cigarette Smoking [0.03%]
定量CT模式和功能丧失与焊接烟雾暴露有关，同时处理卷烟吸烟的混淆效应
Merve Demirci Atik,Abdullah Taylan,Aylin Çifci et al.
Merve Demirci Atik et al.
Introduction: Ill-defined centrilobular nodules, the most common radiological sign of welding fume (WF) exposure, are also frequently seen in smoking-related respiratory bronchiolitis due to their common pathophysiologica...