Candidate genes responsible for lipid droplets formation during adipogenesis simultaneously affect osteoblastogenesis [0.03%]
调控脂滴生成的候选基因同时影响骨形成祖细胞的分化成熟
Xia Yi,Ping Wu,Ying Gong et al.
Xia Yi et al.
Introduction: With cellular lipid storage varying, the balance between lipid intake and lipid degradation was a must to keep healthy and determined the level of lipid droplets. Although lipid droplets accumulation had bee...
Distribution of dopamine-immunoreactive neurons in the brain of the male native Thai chicken [0.03%]
泰国本地公鸡大脑多巴胺免疫反应性神经元的分布特征研究
Boonyarit Kamkrathok,Yupaporn Chaiseha
Boonyarit Kamkrathok
Introduction: Dopamine (DA) is a neurotransmitter/neuromodulator found in both central and peripheral nervous systems. It plays several physiological functions in some mammalian and avian species. DA has been indicated to...
Plasmid-based CRISPR-Cas9 system efficacy for introducing targeted mutations in CD81 gene of MDA-MB-231 cell line [0.03%]
基于质粒的CRISPR-Cas9系统在MDA-MB-231细胞系CD81基因中引入靶向突变的有效性评估
Kasra Arbabi Zaboli,Hossein Rahimi,Jose Thekkiniath et al.
Kasra Arbabi Zaboli et al.
Introduction: Breast cancer has been represented a challenging issue worldwide as it is one of the major leading causes of death among women. CD81 gene, a member of the tetraspanin protein family, has been associated with...
Insulin-like growth factor-1 inhibits apoptosis of rat gastric smooth muscle cells under high glucose condition via adenosine monophosphate-activated protein kinase (AMPK) pathway [0.03%]
胰岛素样生长因子-1通过腺苷单磷酸活化蛋白激酶信号通路抑制高糖环境下大鼠胃壁肌层细胞的凋亡
Xiang-Zi Zhang,Yan Sun,Mo-Han Zhang et al.
Xiang-Zi Zhang et al.
Introduction: Diabetic gastroparesis (DGP) is a common chronic complication of diabetes characterized by decreased gastric motility, and an effective number of gastric smooth muscle cells (GSMCs) ensures gastric motility....
Wnt/PCP pathway regulates the migration and neural differentiation of mesenchymal stem cells in vitro [0.03%]
Wnt/PCP信号通路调控骨髓间充质干细胞的体外迁移和神经分化
Panpan Yao,Qin Yu,Lujie Zhu et al.
Panpan Yao et al.
Introduction: Mesenchymal stem cells (MSCs) are an excellent donor graft source due to their potential for self-renewal and multidirectional differentiation. However, the potential mechanisms involved in MSC homing and ne...
5-fluorouracil suppresses stem cell-like properties by inhibiting p38 in pancreatic cancer cell line PANC-1 [0.03%]
5-氟尿嘧啶通过抑制P38降低胰腺癌细胞系PANC-1的干性特质
Jin Zhao,Xueying Shi,Changcheng Dong et al.
Jin Zhao et al.
Introduction: Suppressing the phenotype of cancer stem cells (CSCs) is a promising treatment strategy for cancer. P38 mitogen-activated protein kinases (MAPK, p38) play an important role in the occurrence, development, an...
EID1 plays a protective role in early-onset pre-eclampsia via promoting proliferation and invasion in trophoblast cells [0.03%]
EID1通过促进滋养细胞的增殖和侵袭在早发型子痫前期中发挥保护作用
Ying Li,Jiuxiang Feng,Yue Bian et al.
Ying Li et al.
Introduction: Pre-eclampsia is a pregnancy-specific syndrome, which is partly due to abnormal proliferation and invasion of trophoblast cells. EP300 interacting inhibitor of differentiation 1 (EID1) participates in cell p...
Differential apoptotic activity in trophoblast of spontaneous abortions and normal pregnancies [0.03%]
自然流产和正常妊娠滋养细胞凋亡活性的差异性研究
Theodora-Eleftheria Deftereou,Avgi Tsolou,Anastasios Liberis et al.
Theodora-Eleftheria Deftereou et al.
Introduction: Apoptosis is a key process during normal trophoblastic development and, consequently, the whole gestation. However, in trophoblastic differentiation in spontaneous abortions apoptosis has been hardly investi...
Overexpression of IL-8 and Wnt2 is associated with prognosis of gastric cancer [0.03%]
白细胞介素8和Wnt2高表达与胃癌预后有关
Li Lin,Linjing Li,Gui Ma et al.
Li Lin et al.
Introduction: This study is to detect the expression of inflammatory factor or neutrophil-activating factor IL-8 and Wnt2 in gastric cancer (GC) and investigate the involvement of IL-8 and Wnt2 expressions in the clinicop...
Soyasaponin Ag inhibits triple-negative breast cancer progression via targeting the DUSP6/MAPK signaling [0.03%]
黄豆皂苷Ag通过靶向DUSP6/MAPK信号通路抑制三阴性乳腺癌进展
Shoucheng Huang,Ping Huang,Huazhang Wu et al.
Shoucheng Huang et al.
Introduction: Soyasaponins are triterpenoid glycosides discovered in soybean and have anti-cancer properties. Soyasaponin A was reported to repress estrogen-insensitive breast cancer cell proliferation. This study intends...