HDAC6 inhibition alleviates acute pulmonary embolism: a possible future therapeutic option [0.03%]
组蛋白去乙酰化酶6抑制剂可能成为新的肺栓塞治疗手段
Tao Zhou,Di Jia,Jiahui Han et al.
Tao Zhou et al.
Introduction: Acute pulmonary embolism (APE) is a clinical syndrome of pulmonary circulation disorder caused by obstruction of the pulmonary artery or its branches. Histone deacetylase 6 (HDAC6) has been reported to play ...
Focused ultrasound restrains the growth of orthotopic colon cancer via promoting pyroptosis [0.03%]
磁定位聚焦超声通过促进焦亡抑制原位结肠癌生长
Weixing Mo,Qingqing Yu,Xiufeng Kuang et al.
Weixing Mo et al.
Introduction: Focused ultrasound (FUS) is a non-invasive tumor therapy technology emerging in recent years, which can treat various solid tumors. However, it is unclear whether FUS can affect the pyroptosis of colon cance...
Periostin in ovarian carcinoma: from heterogeneity to prognostic value [0.03%]
卵巢癌中的periostin：从异质性到预后价值
Ludmila Lozneanu,Irina-Draga Caruntu,Cornelia Amalinei et al.
Ludmila Lozneanu et al.
Introduction: Periostin (POSTN), an extracellular matrix protein, is involved in tumor-associated extracellular matrix (ECM) remodeling. However, its potential value as a prognostic and/or predictive factor has not yet be...
6-Gingerol attenuates sepsis-induced acute lung injury by suppressing NLRP3 inflammasome through Nrf2 activation [0.03%]
姜辣素通过激活Nrf2抑制NLRP3炎性小体从而改善脓毒症诱导的急性肺损伤
Quanli Pan,Peng Liu,Min Wan
Quanli Pan
Introduction: Sepsis is characterized by an overactive inflammatory response. Acute lung injury (ALI) is the most common type of organ injury in sepsis, with high morbidity and mortality. 6-Gingerol is the main bioactive ...
Morphology and immunohistochemical characteristics of the otic ganglion in the chinchilla (Chinchilla laniger Molina) [0.03%]
筒子狸(ChinchillalanagerMolina)耳神经节的形态和免疫组织化学特征
Waldemar Sienkiewicz,Jacek Kuchinka,Agnieszka Dudek et al.
Waldemar Sienkiewicz et al.
Introduction: The available literature provides relatively little information on the morphology of the autonomic head ganglia in rodents including their neurochemical codding. ...
Overexpressing six-transmembrane protein of prostate 2 (STAMP2) alleviates sepsis-induced acute lung injury probably by hindering M1 macrophage polarization via the NF-κB pathway [0.03%]
六跨膜前列腺蛋白2过表达通过抑制NF-κB通路的M1巨噬细胞极化从而缓解脓毒症诱导的急性肺损伤的可能性研究
Lili Ji,Xiaojing Shi,Gaopin Wang et al.
Lili Ji et al.
Introduction: Acute lung injury (ALI) is a major cause of death in sepsis patients. The Six-transmembrane protein of prostate 2 (STAMP2) is a key regulator of inflammation, while its role in septic ALI remains unclear. ...
FUCA2 and TSTA3 expression in gastric cancer: candidate biomarkers of malignant transformation [0.03%]
胃癌中FUCA2和TSTA3的表达：恶性转化的候选生物标志物
Michael Williames Leal Quirino,Amanda Pinheiro de Barros Albuquerque,Maria de Fátima Deodato de Souza et al.
Michael Williames Leal Quirino et al.
Introduction: Aberrant fucosylation is closely related to malignant transformation, cancer detection, and evaluation of treatment efficacy. The fucosylation process requires GDP-L-fucose, fucosyltransferases, and fucosida...
Zbigniew Kmieć
Zbigniew Kmieć
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis [0.03%]
黄芪甲苷IV介导的内皮祖细胞外泌体通过miR-21/PTEN轴促进自噬并抑制高血糖损伤的内皮细胞凋亡
Wu Xiong,Xin-Ling Huang,Cheng-Yu Li et al.
Wu Xiong et al.
Introduction: As one of the basic components of Astragalus, Astragaloside IV (AS-IV) has a protective effect on endothelial injury caused by diabetes. AS-IV stimulated endothelial progenitor cells (EPCs) to secrete exosom...
Dexmedetomidine alleviates intestinal barrier dysfunction and inflammatory response in mice via suppressing TLR4/MyD88/NF-κB signaling in an experimental model of ulcerative colitis [0.03%]
右美托咪定通过抑制TLR4/MyD88/NF-κB信号缓解溃疡性结肠炎小鼠模型的肠道屏障功能障碍和炎症反应
Xiaojin Ye,Huailiang Xu,Yuan Xu
Xiaojin Ye
Introduction: Ulcerative colitis (UC) is a nonspecific intestinal inflammatory disease. Dexmedetomidine (DEX) is a selective alpha 2-adrenergic receptor agonist commonly used for analgesia and sedation in intensive care u...