Periplaneta americana extract attenuates hepatic fibrosis progression by inhibiting collagen synthesis and regulating the TGF-β1/Smad signaling pathway [0.03%]
美洲蜚蠊提取物通过抑制胶原合成及调节TGF-β1/Smad信号通路干预肝纤维化进展
Yi Chen,Yanwen Zhao,Liping Yuan et al.
Yi Chen et al.
Introduction: Liver fibrosis is the damage repair response following chronic liver diseases. Activated hepatic stellate cells (HSCs) are the main extracellular matrix (ECM)-producing cells and key regulators in liver fibr...
Therapeutic effect of autophagy induced by rapamycin versus intermittent fasting in animal model of fatty liver [0.03%]
雷帕霉素和间歇性禁食诱导自噬对脂肪肝模型小鼠的治疗效果比较研究
Sara Adel Hosny,Mohammed Hafez Ahmed Moustafa,Fatma Mahmoud Mehina et al.
Sara Adel Hosny et al.
Introduction: High-fructose, high-fat diet consumption (HFHF) is one of the primary causes of non-alcoholic fatt liver disease (NAFLD), which is due to impaired beta-oxidation or apolipoprotein secretion by hepatocytes. A...
Inhibition of autophagy promotes sonodynamic therapy-induced apoptosis of pancreatic cancer cells [0.03%]
自噬抑制能促进声动力疗法诱导的胰腺癌细胞凋亡
Xiaoxue Du,Jiaming Song,Ziwen Zhang et al.
Xiaoxue Du et al.
Introduction: Sonodynamic therapy (SDT), a promising non-invasive therapeutic modality, has attracted increasing attention in the treatment of pancreatic cancer (PC). At present, the role of autophagy in SDT of PC remains...
Therapeutic effect of exosomes derived from hepatocyte-growth-factor-overexpressing adipose mesenchymal stem cells on liver injury [0.03%]
由过表达肝细胞生长因子的脂肪间充质干细胞来源的外泌体对肝脏损伤的治疗作用
Liushenyan Yu,Junchao Xue,Yanyan Wu et al.
Liushenyan Yu et al.
Adipose mesenchymal stem cell-derived exosomes (ADMSC-Exo) are a new strategy for the treatment of liver injury. However, mesenchymal stem cells (MSCs) exert therapeutic effects mainly by secreting hepatocyte growth factor (HGF). Therefore,...
Expression of CD105 but not of E-cadherin is associated with malignancy recurrence and disease-free interval in laryngeal cancer in men [0.03%]
CD105的表达但不是E-钙粘蛋白的表达与男性喉癌的恶性复发和无病期有关
Elvir Zvrko,Ljiljana Vuckovic
Elvir Zvrko
Introduction: In this study we analyzed CD105 (endoglin) and E-cadherin expression in laryngeal squamous cell carcinoma (LSCC) to evaluate their clinicopathologic significance. ...
Inhibition of heat shock protein 47 suppressed collagen production in Tenon's capsule fibroblasts [0.03%]
热休克蛋白47抑制对Tenon氏层纤维细胞中胶原生成的抑制作用研究
Weiwei Wang,Haiyan lI
Weiwei Wang
Introduction: Glaucoma is the leading cause of irreversible blindness worldwide, and conjunctival bleb scarring remains the most frequent reason for the failure of glaucoma filtration surgery. Excessive proliferation of f...
Curcumin exerts protective effects on the thyroid gland in propylthiouracil-treated rats [0.03%]
姜黄素对 Propylthiouracil诱导的实验性甲状腺毒症大鼠甲状腺保护作用的研究
Monika A Papież
Monika A Papież
Introduction: Among the plant ingredients, some compounds interfere with the functions of the thyroid gland. However, there is limited research on the effect of curcumin (CMN) on the functions of this gland. The aim of th...
Rare benign lung tumours presenting with high clinical suspicion for malignancy: a case series and review of the literature [0.03%]
高度怀疑恶性肿瘤的罕见良性肺肿瘤病例系列及文献回顾
Katarina Popovic,Mirjana Miladinović,Ljiljana Vučković et al.
Katarina Popovic et al.
Introduction: Incidentally discovered lung nodules can be worrisome for both the patient and their physicians. Although 95% of solitary lung nodules are benign, it is important to distinguish which nodules have high clini...
The effectiveness of using dye models for small tissue biopsies in the surgical pathology laboratory [0.03%]
染料模型在手术病理实验室中小组织活检中的有效性研究
Predaporn Nonsiri,Potchara Srivilai,Supatsorn Onkaew et al.
Predaporn Nonsiri et al.
Introduction: Losing of small tissues during tissue preparatory steps may seriously affect pathological diagnostic performance. Using an appropriate tissue marking dye could be an alternative solution. Therefore, the aim ...
Cryptotanshinone ameliorates hemorrhagic shock-induced liver injury via activating the Nrf2 signaling pathway [0.03%]
cryptotanshinone通过激活nrf2信号途径改善出血性休克所致肝损伤
Jiahui Han,Di Jia,Hao Yao et al.
Jiahui Han et al.
Introduction: Hemorrhagic shock (HS) is an important cause of high mortality in traumatized patients. Cryptotanshinone (CTS) is a bioactive compound extracted from Salvia miltiorrhiza Bunge (Danshen). The current study ai...