CCL19 promotes TNF-alpha/IFN-gamma-induced production of cytokines by targeting CCR7/NF-κB signalling in HaCaT cells [0.03%]
CCL19通过靶向CCR7/NF-κB信号通路促进TNF-α/IFN-γ诱导的HaCaT细胞中细胞因子产生
Ying Zeng,Xiaoqi Nie,Yunhua Deng
Ying Zeng
Introduction: Atopic dermatitis (AD) is the most common allergic skin disease. The dysfunction of keratinocytes is closely associated with AD progression. Nevertheless, the specific functions of CC chemokine ligand 19 (CC...
OGFr overexpression exerts anti-hepatocellular carcinoma effects by activating P16 and P21 to inhibit proliferation and migration of HepG2 cells [0.03%]
过表达OGFr通过活化P16和P21抑制HepG2细胞增殖及迁移的抗肝癌作用
Zhezhu Jin,Yongjun Jin
Zhezhu Jin
Introduction: Hepatocellular carcinoma (HCC) is the sixth most common type of cancer and the second leading cause of cancer death worldwide [19]. Opioid growth factor (OGF) has been shown to exhibit antitumour potential, ...
Anti-atherosclerotic effects of LncRNA NEXN-AS1 by regulation of the canonical inflammasome pathway of pyroptosis via NEXN [0.03%]
长链非编码RNA NEXN-AS1通过调节NEXN介导的经典的炎性小体途径抑制动脉粥样硬化形成的作用及机制研究
Fei Chen,Yun-Yong Lin,Rui Chen et al.
Fei Chen et al.
Introduction: . Pyroptosis is closely related to many chronic diseases including atherosclerosis, but the potential pathomechanisms are still unclear. This research aimed to explore how lncRNAs may contribute to pyroptosi...
Long non-coding RNA HOTAIR promotes tumorigenesis by affecting proliferation, invasion, migration and apoptosis of liver cancer cells [0.03%]
长链非编码RNA HOTAIR通过影响肝癌细胞的增殖、浸润、转移和凋亡促进肿瘤发生发展
Xinzi Zheng,Renyin Cui,Yan Jiao et al.
Xinzi Zheng et al.
Introduction: Increasing evidence shows that Hox transcript antisense RNA (HOTAIR) plays a vital role in liver cancer initiation and progression by affecting the proliferation, invasion, migration and apoptosis of liver c...
Changes in early endosomes in rat hippocampal CA1 neurons after transient global cerebral ischaemia [0.03%]
短暂全脑缺血后大鼠海马CA1神经元早期早期内体的变化
Min Qiang,Bai-Hong Tan,De-Sheng Huo et al.
Min Qiang et al.
Introduction: Transient global ischaemia in rodents causes selective loss of hippocampal CA1neurons, but the potential involvement of endocytic pathways has not been fully explored. The aim of this study was to investigat...
Identification of an active fraction of Kangfuxin in the treatment of periodontitis in a rat model [0.03%]
カンフシンによる歯周炎治療における有効成分の同定
Yanli Tang,Jie Pan,Hui Guo et al.
Yanli Tang et al.
Introduction: Periodontitis is a serious gum infection that disrupts the soft tissue around teeth. This study aimed to identify the most effective fraction of the Chinese medicine Kangfuxin for periodontitis treatment in ...
Nootkatone mitigates periodontal inflammation and reduces alveolar bone loss via Nrf2/HO-1 and NF-κB pathways in rat model of periodontitis [0.03%]
香豆净通过Nrf2 / HO-1和NF-κB途径减轻牙周炎模型大鼠的牙周炎症并减少牙槽骨吸收
Ye Yin,Zeyu Ma,Peiliang Shi
Ye Yin
Introduction: Periodontitis (PD) is a chronic inflammatory disease leading to alveolar bone loss. This study investigated the effect of nootkatone and regulatory mechanism in reducing periodontal inflammation and alveolar...
Platelet-rich plasma ameliorates cartilage degradation in rat models of osteoarthritis via the OPG/RANKL/RANK system [0.03%]
富血小板血浆通过OPG/RANKL/RANK系统改善骨关节炎模型大鼠软骨降解
Qun Wu,Xianbao Yao,Nan Shan et al.
Qun Wu et al.
Introduction: Osteoarthritis (OA) is one of the most common degenerative joint diseases in the elderly, which is featured by the degradation of articular cartilage. Recently, platelet-rich plasma (PRP) injection into the ...
Dioscin attenuates lupus nephritis in NZB/W F1 mice by decreasing NF-κB activation and NLRP3 inflammasome [0.03%]
原花青素通过降低NF-κB活化和NLRP3炎性小体减轻NZB/WF1鼠狼疮性肾炎
Yaling Xu,Han Li
Yaling Xu
Introduction: Dioscin, a natural steroid saponin, has anticancer, anti-inflammatory, anti-hyperlipidemic, and glycemic capabilities. This study focused on dioscin roles and its related mechanisms in experimental lupus nep...
Digital morphology network for effective teaching of cytology, histology and histopathology for medical and biology curriculum. VM3.0 Erasmus+ project [0.03%]
数字化形态学网络在医学及生物课程细胞学、组织学和组织病理学有效教学中的应用——VM3.0erasmus+项目
Cornelia Amalinei,Andrei Daniel Timofte,Irina Draga Caruntu et al.
Cornelia Amalinei et al.
Introduction: Digital microscopy transformation, the basis for the virtual microscopy applications, is a challenge but also a requirement in modern Medical Education. This paper presents the scope, background, methods, an...