Molecular landscape of the mouse adrenal gland and adjacent adipose tissue by spatial transcriptomics [0.03%]
空间转录组学绘制小鼠肾上腺和邻近脂肪组织的分子图谱
Malgorzata Blatkiewicz,Szymon Hryhorowicz,Marta Szyszka et al.
Malgorzata Blatkiewicz et al.
Introduction: . The adrenal glands are central regulators of endocrine homeostasis and stress adaptation. Despite decades of research, the molecular mechanisms governing adrenal zonation and cortical renewal remain incomp...
Critical assessment of microscopy methods for detecting single- and double-strand DNA breaks [0.03%]
显微技术鉴定单链和双链DNA损伤的批判性评估
Agnieszka Hoang-Bujnowicz,Julita Wesolowska,Agnieszka Ostromecka et al.
Agnieszka Hoang-Bujnowicz et al.
A laboratory toolbox for detecting and quantifying DNA breaks in animal cells and tissues includes various methods that employ biochemical tests, DNA sequencing, or imaging approaches. Various methods based on microscopy were developed to d...
VE1 immunohistochemistry as a screening tool for BRAFV600E mutation in lung adenocarcinoma: evidence from a Montenegro National Cohort [0.03%]
BRAFV600E突变的筛选标志物VE1免疫组织化学在肺癌腺癌中的应用——一项来自黑山共和国的全国队列研究证据
Branko Campar,Mirjana Miladinovic,Janja Raonic et al.
Branko Campar et al.
Introduction: Lung cancer remains the leading cause of cancer-related mortality worldwide, with non-small cell lung cancer (NSCLC) representing the majority of cases. Molecular profiling of NSCLC has identified multiple g...
Immunohistochemical and histopathological characteristics of adenomas and adenocarcinomas of Meibomian glands in dogs [0.03%]
犬眼睑腺腺瘤和腺癌的免疫组织化学和组织病理学特征
Rafal Ciaputa,Adam Szymerowski,Kacper Zebrowski et al.
Rafal Ciaputa et al.
Introduction: This study aimed to provide a comprehensive histopathological and immunohistochemical analysis of Meibomian adenomas and adenocarcinomas. Ma...
Tectochrysin alleviates high-glucose-induced retinal pigment epithelial cell injury through Nrf2/HO-1 activation [0.03%]
黄酮类化合物TECT通过激活Nrf2/HO-1信号减轻高糖诱导的视网膜色素上皮细胞损伤
Yuan Sui,Chengsen Zhang,Bingbing Jiang et al.
Yuan Sui et al.
Introduction: Diabetic retinopathy involves retinal pigment epithelium (RPE) dysfunction. Tectochrysin is a natural flavonoid and antioxidant. However, its effects on retinal pigment epithelial cells remain unveiled. In t...
Aggressiveness of papillary thyroid carcinoma: a comprehensive analysis from molecular mechanisms to clinical applications [0.03%]
乳头状甲状腺癌的侵袭性：从分子机制到临床应用的全面分析
Min Wang,Bin Li
Min Wang
Papillary thyroid carcinoma (PTC) constitutes the predominant subtype among thyroid malignancies. Despite its generally favorable prognosis, certain aggressive subtypes, along with recurrent and metastatic manifestations, substantially affe...
Genetic alterations in papillary thyroid cancer: clinicopathological correlations and diagnostic implications [0.03%]
乳头状甲状腺癌的遗传改变：临床病理相关性及诊断意义
Enaam Mohammed Ali Junainah
Enaam Mohammed Ali Junainah
Introduction: Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy, encompassing distinct histological variants and a wide spectrum of clinical behaviors. Advances in molecular diagnostics have identifi...
Electroacupuncture ameliorates depressive-like behaviors by activating Sirt1 to enhance oligodendrocyte differentiation and myelination in the prefrontal cortex of rats [0.03%]
电针通过激活Sirt1促进前额叶皮质少突胶质细胞分化和髓鞘化从而改善大鼠抑郁样行为
Hui-Qian Cai,Tian Wang,Li-Xia Lin et al.
Hui-Qian Cai et al.
Introduction: This study investigated the therapeutic mechanisms of electroacupuncture (EA) in chronic unpredictable stress (CUS)-induced depression rat model. Since SIRT1 plays in oligodendrocyte differentiation and neur...
Potential O GlcNAcylation and odontoblast differentiation in dental pulp stem cells [0.03%]
牙髓干细胞中O-GlcNAc化对诱导分化为牙本质细胞的潜能的影响
María Teresa Hernández-Huerta,Laura Pérez-Campos Mayoral,Hector Alejandro Cabrera-Fuentes et al.
María Teresa Hernández-Huerta et al.
Electroacupuncture stimulation inhibited astrogliosis and microglia polarisation to alleviate spinal cord injury via Janus kinase 2/signal transducer and activator of transcription 3 signalling pathway [0.03%]
电针通过Janus激酶2/信号转导及转录激活因子3信号通路抑制星形胶质细胞增生和小胶质细胞极化以缓解脊髓损伤
Jianuo Li,Yuhuai Guo,Xiangxin Zeng et al.
Jianuo Li et al.
Introduction: The aberrant activation of the Janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) signalling pathway is involved in spinal cord injury (SCI) progression. Electroacupuncture (EA) s...