Characteristics and patterns of adverse event reports in the Japanese Adverse Drug Event Report database over two decades (2004-2023): Exploring findings on sexes and age groups [0.03%]
日本不良药物事件报告数据库中二十多年来（2004-2023）不良事件报告的特点和模式：探索性别和年龄段的发现
Hiroyuki Tanaka,Masaki Takigawa,Naohito Ide et al.
Hiroyuki Tanaka et al.
Recently, increased attention has been paid to the consideration of individual characteristics, including sex and age, in the context of medication use and adverse events. However, the characteristics and patterns of adverse events reported...
Emulsification-based liposomal formulation of gallic acid and curcumin as potent topical antioxidants [0.03%]
基于乳化的棓酸和姜黄素脂质体配方作为一种有效的外用抗氧化剂
Takron Chantadee,Siripat Chaichit,Kanokwan Kiattisin et al.
Takron Chantadee et al.
Excessive free radicals in the skin cause oxidative stress, damaging cells and leading to aging, melasma, and inflammation. This study developed a liposome system for co-delivering antioxidants to enhance their efficacy in deeper skin layer...
Decreased serum calcium levels predict severe complications after initial diagnosis in patients with acute type B aortic dissection: A retrospective cohort study [0.03%]
急性B型主动脉夹层患者初始诊断后严重并发症的血钙水平预测因子：一项回顾性队列研究
Fangzheng Meng,Liang Fang,Jing Zhou et al.
Fangzheng Meng et al.
This study sought to investigate the temporal variations in serum calcium concentrations among patients with acute type B aortic dissection (ATBAD) following initial diagnosis, document the incidence of severe complications, and evaluate th...
Isolation and characterization of phosphoglycerate kinase and creatine kinase from bighead carp (Aristichthys nobilis): Potential sources for antitumor agents [0.03%]
草鱼3-磷酸甘油酸激酶和肌酸激酶的分离与鉴定：潜在的抗肿瘤药物来源
Yue Gao,Wanying Liu,Qing Yan et al.
Yue Gao et al.
Bighead carp (Aristichthys nobilis) has garnered significant attention due to its potential health benefits, yet its bioactive protein components remain largely unexplored. In this study, two proteins S3 and Z1 were isolated from Aristichth...
Imaging and serum antigen levels that influence the treatment and prognosis of cryptococcosis in immunocompetent and immuno-compromised patients: A 10-year retrospective study [0.03%]
免疫功能正常和免疫功能缺陷患者隐球菌病治疗及预后的影像学和血清抗原水平变化：一项十年回顾性研究
Yi Su,Meixia Wang,Qingqing Wang et al.
Yi Su et al.
This article was to summarize the treatment course and prognosis of immunocompetent and immunocompromised patients with pulmonary cryptococcal infections and to analyse the relevant factors. The chisquared test was used to test for differen...
Fosfomycin-associated adverse events: A disproportionality analysis of the FDA Adverse Event Reporting System [0.03%]
膦霉素相关的不良反应事件：FDA不良反应报告系统中的比例分析
Luxuan Yang,Wenyong Zhang,Xiujuan Shen et al.
Luxuan Yang et al.
Fosfomycin, with its unique mechanism of action, has emerged as a promising option for clinicians to combat antimicrobial resistance and the limited availability of effective drugs, which has led to an increase in associated adverse events ...
Human gut associated Bacteroides and Akkermansia bacteria exhibit immunostimulatory activity in the silkworm muscle contraction assay [0.03%]
与人类肠道相关的Bacteroides和Akkermansia细菌在蚕肌肉收缩试验中表现出免疫刺激活性
Fumiaki Tabuchi,Chie Kano,Tatsuhiko Hirota et al.
Fumiaki Tabuchi et al.
Suzetrigine: The first Nav1.8 inhibitor approved for the treatment of moderate to severe acute pain [0.03%]
苏泽曲林：首个获批用于中重度急性疼痛治疗的Nav1.8抑制剂
Shasha Hu,Dong Lyu,Jianjun Gao
Shasha Hu
Opioids are commonly prescribed for the management of moderate to severe pain, but their use is associated with dependency and other adverse effects. For decades, the development of safe and effective non-addictive alternatives for treating...
A pharmacovigilance study based on the FAERS database focusing on anticoagulant and hormonal drugs that induce vaginal hemorrhage [0.03%]
基于FAERS数据库的药物警戒研究：关注引起阴道出血的抗凝血药和激素类药物
Ruohan Li,Panwei Hu,Lin Qian
Ruohan Li
Numerous medications have been associated with an increased risk of vaginal hemorrhage in women. In this study, we analyzed data from the FDA Adverse Event Reporting System (FAERS), focusing on reports of drug-induced vaginal bleeding in wo...
Long-term renoprotective effect of luseogliflozin in type 2 diabetes patients: CHikushi Anti-diabetes mellitus Trial-Lusefi (CHAT-Lu) [0.03%]
卢格列净对2型糖尿病患者的长期肾脏保护作用：CHKTM-Lu研究
Yosuke Takamiya,Chiyori Imanaga,Ichiro Abe et al.
Yosuke Takamiya et al.
Several sodium-glucose cotransporter 2 (SGLT2) inhibitors are known to have beneficial effects on renal function in patients with type 2 diabetes. However, the long-term effects of luseogliflozin, an SGLT2 inhibitor, remain uncertain in rea...