Status of use of protease inhibitors for the prevention and treatment of pancreatitis after endoscopic retrograde cholangiopancreatography: An epidemiologic analysis of the evidence-practice gap using a health insurance claims database [0.03%]
内镜逆行胰胆管造影后使用蛋白酶抑制剂预防和治疗急性胰腺炎的现状：一项关于证据-实践差距的流行病学分析（基于健康保险理赔数据库）
Takeshi Seta,Yoshimitsu Takahashi,Yukitaka Yamashita et al.
Takeshi Seta et al.
Existing evidence suggests that protease inhibitors (PIs) used to prevent or treat pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP) are ineffective, and their use is not recommended by clinical practice guidelines. H...
Additive effects of Kothala himbutu (Salacia reticulata) extract and a lactic acid bacterium (Enterococcus faecalis YM0831) for suppression of sucrose-induced hyperglycemia in an in vivo silkworm evaluation system [0.03%]
丝瓜络提取物与肠球菌（枯蚕模型）联合降血糖作用研究
Masaki Ishii,Yasuhiko Matsumoto,Toshiaki Katada et al.
Masaki Ishii et al.
Using a silkworm evaluation system, we previously evaluated various substances that suppress postprandial hyperglycemia. Enterococcus faecalis YM0831, a lactic acid bacterium that inhibits glucose uptake by the human intestinal Caco-2 cell ...
Generic selection criteria for safety and patient benefit [VIII]: Comparing the physicochemical and pharmaceutical properties of brand-name and generic diclofenac sodium tapes [0.03%]
关于安全性和患者疗效的通用选择标准[VIII]：比较品牌与仿制双氯芬酸钠贴剂的理化及药学性质
Mitsuru Nozawa,Miho Goto,Yuko Wada et al.
Mitsuru Nozawa et al.
With respect to diclofenac sodium-containing tape preparations of nonsteroidal antiphlogistic drug, we compared the pharmaceutical properties (pH, elongatedness, water-vapor permeability, adhesive force, and peeling-force) of 11 medicinal d...
Comparative Study
Drug discoveries & therapeutics. 2019 Jul 22;13(3):150-156. DOI:10.5582/ddt.2019.01035 2019
Rapid temporal improvement of pembrolizumab-induced pneumonitis using the anti-TNF-α antibody infliximab [0.03%]
利用抗TNF-α抗体英夫利昔单抗快速改善派姆单抗致肺炎的症状
Yutaka Sawai,Yuki Katsuya,Aya Shinozaki-Ushiku et al.
Yutaka Sawai et al.
Immune checkpoint inhibitors are associated with a wide spectrum of immune-related adverse events (irAEs) that are typically transient but are sometimes severe or even fatal. No consensus exists for the treatment of severe immune-mediated p...
Molecular characterization of multi-drug resistant coagulase negative cocci in non-hospital environment [0.03%]
非医院环境中的多重耐药凝固酶阴性葡萄球菌的分子特征分析
Daniel Don Nwibo,Suresh Panthee,Hiroshi Hamamoto et al.
Daniel Don Nwibo et al.
Antibiotic resistance crisis occasioned by sporadic appearance of multi-drug resistance (MDR) in human pathogens to clinically applied antimicrobials is a serious threat to global health. In this study, we investigated the drug resistant ph...
Immediate antiviral therapy for HIV-infected persons faces with various obstacles [0.03%]
面对各种障碍，艾滋病病毒感染者需要立即接受抗病毒治疗
Qi Tang,Hongzhou Lu
Qi Tang
Human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) ranks eighth in the global burden of disease, making seriously threatens to global health. Given there is not yet a cure for HIV infection, antiretroviral therapy...
A survey on awareness of the "finger-tip unit" and medication guidance for the use of topical steroids among community pharmacists [0.03%]
社区药师关于"指尖单位"知晓情况及皮质类固醇外用药物使用指导调查研究
Nobuo Oishi,Hiroki Iwata,Noriko Kobayashi et al.
Nobuo Oishi et al.
Atopic dermatitis (AD) is a common chronic, pruritic inflammatory skin condition. AD is most commonly treated with topical corticosteroids, and the finger-tip unit (FTU) should be used as a guideline for the amount to be used per applicatio...
Infectious versus non-infectious causes of oligoarticular inflammatory arthritis: A prospective study from a tertiary care hospital in north India [0.03%]
印度北部一家三级护理医院的前瞻性研究：少关节炎性关节炎的感染性和非感染性原因
Nitin Gupta,Rama Chaudhry,Manish Soneja et al.
Nitin Gupta et al.
Oligoarticular arthritis (inflammation of upto 4 joints) has a wide range of infectious and non-infectious etiologies. The aim of our study was to identify the features which could help in the differentiation of infectious from non-infectio...
Observational Study
Drug discoveries & therapeutics. 2019;13(2):96-100. DOI:10.5582/ddt.2019.01019 2019
A study on factors determining dose of topical lignocaine during broncho-alveolar lavage by spray-as-you-go technique: A single centre observational study [0.03%]
一次性给药法支气管肺泡灌洗过程中外用利多卡因剂量的影响因素分析：单中心观察性研究
Animesh Ray,Samagra Agarwal,Sagnik Biswas et al.
Animesh Ray et al.
Basic bronchoscopic diagnostic procedures like Broncho-alveolar lavage (BAL) are often performed without sedation, using lignocaine administered via the working channel of bronchoscope (spray-as-you-go technique) and other routes. Our aim w...
Observational Study
Drug discoveries & therapeutics. 2019;13(2):89-95. DOI:10.5582/ddt.2019.01012 2019
Paraoxonase 1 gene (Q192R) polymorphism confers susceptibility to coronary artery disease in type 2 diabetes patients: Evidence from case-control studies [0.03%]
帕欧酸酯酶1基因多态性与2型糖尿病患者冠心病易感性的相关性研究：病例对照研究证据
Xiaowei Huo,Yuan Guo,Yongjian Zhang et al.
Xiaowei Huo et al.
Numerous published studies have investigated the relationship between the paraoxonase 1 (PON1) gene Q192R (rs662) polymorphism and the risk of coronary artery disease (CAD) in type 2 diabetes mellitus (T2DM) patients. However, the results a...