Treat 2019 novel coronavirus (COVID-19) with IL-6 inhibitor: Are we already that far? [0.03%]
用IL-6抑制剂治疗新型冠状病毒（COVID-19）感染者：我们已经准备好了吗？
Yuanyuan Zhang,Yanyan Zhong,Lin Pan et al.
Yuanyuan Zhang et al.
The world is in the midst of the coronavirus disease 2019 (COVID-19) pandemic. Interleukin 6 (IL-6) inhibitor (tocilizumab) had been suggested for the treatment of acute respiratory distress syndrome (ARDS) patients based on the concept of ...
A systematic review on anti-Alzheimer's disease activity of prescription Kangen-karyu [0.03%]
关金贵方抗阿尔茨海默病活性的系统评价
Pradeep Paudel,Chan Hum Park,Hyun Ah Jung et al.
Pradeep Paudel et al.
Traditional Chinese and Japanese medicines have become prime sources of drug discovery and there is a pressing need to investigate the effectiveness of these traditional medicines for modern drug discovery. Recently, among various tradition...
Waquar Ahsan,Shamama Javed,Mohammed Al Bratty et al.
Waquar Ahsan et al.
The virus severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is currently affecting more than 200 countries and territories worldwide. It has been declared as pandemic by World Health Organization (WHO) and the whole world is suff...
Is GSK3β a molecular target of chloroquine treatment against COVID-19? [0.03%]
氯喹治疗COVID-19的分子靶点是GSK3β吗？
Mohammed Noor Embi,Nagesswary Ganesan,Hasidah Mohd Sidek
Mohammed Noor Embi
The recent clinical trial reports pertaining to the efficacy of chloroquine and hydroxychloroquine against COVID-19 albeit yet to be validated with larger clinical trials, have sparked much interest globally to evaluate whether this anti-ma...
Brain abscess in patients with chronic kidney disease: A case-based approach to management in resource-limited settings [0.03%]
慢性肾病患者脑脓肿的管理：资源有限情况下的病例分析方法
Nitin Gupta,Rohit Kumar,Sayantan Banerjee et al.
Nitin Gupta et al.
The management of patients with brain abscess poses a significant challenge to clinicians in patients with chronic kidney disease. Obtaining a biopsy sample from the affected area is the mainstay in the diagnosis, but it is often unavailabl...
Ultra-low price of generic agents in China may weaken patients' drug recognition and compliance [0.03%]
廉价仿制药对中国患者的用药依从性产生不利影响
Saihua Lu,Jian Cai,Feng Xu
Saihua Lu
Drug quantity purchase in China has reshaped the pattern of drug market with lower price of generic drugs and relatively higher price of original brand-name drugs. However, most Chinese people do not trust the safety and efficacy of the gen...
Gustavo H Marin
Gustavo H Marin
Based on some publications that associate SARS-CoV-2 infection with the use of anti-hypertensive drug groups such as angiotensin-converting-enzyme inhibitors (e.g. enalapril) or angiotensin II receptor blockers (e.g. losartan), many patient...
Polysaccharides of a fermented food, natto, suppress sucrose-induced hyperglycemia in an in vivo evaluation system and inhibit glucose uptake by human intestinal cells [0.03%]
发酵食品纳豆多糖抑制体内评价系统中的蔗糖所致高血糖及人体肠细胞葡萄糖摄取
Yasuhiko Matsumoto,Miki Takahashi,Kazuhisa Sekimizu
Yasuhiko Matsumoto
Natto is a well-known traditional Japanese food produced by fermenting soybeans with Bacillus subtilis var natto. Here we found that the water-soluble viscous fraction of natto inhibits sucrose- or glucose-induced hyperglycemia in silkworms...
Discovering drugs to treat coronavirus disease 2019 (COVID-19) [0.03%]
用于治疗冠状病毒疾病2019（COVID-19）的药物发现
Liying Dong,Shasha Hu,Jianjun Gao
Liying Dong
The SARS-CoV-2 virus emerged in December 2019 and then spread rapidly worldwide, particularly to China, Japan, and South Korea. Scientists are endeavoring to find antivirals specific to the virus. Several drugs such as chloroquine, arbidol,...
Development of an algorithm using ultrasonography-assisted peripheral intravenous catheter placement for reducing catheter failure [0.03%]
利用超声引导外周静脉导管置入以减少导管故障的算法建立
Chiho Kanno,Ryoko Murayama,Mari Abe-Doi et al.
Chiho Kanno et al.
Up to 50% peripheral intravenous catheters (PIVs) are removed prematurely because of failures. Catheter failure (CF) leads to replacement and is a great concern for patients and medical staff. It is known that visualization of catheters and...