Beneficial impact of visual stimulation-based digital therapeutics on blood pressure control in non-hypertensive individuals [0.03%]
基于视觉刺激的数字疗法对非高血压患者血压控制的积极作用
Yiwen Jiang,Hong Liu,Lingrui Yang et al.
Yiwen Jiang et al.
Hypertension-related diseases occur in both hypertensive and non-hypertensive individuals. However, few studies to date have explored blood pressure (BP) control in non-hypertensive individuals. This before-after study aimed to examine the ...
Yishen Huatan Huoxue decoction and quercetin ameliorate decidualization dysfunction in polycystic ovary syndrome: A comprehensive investigation combining clinical trial and experimental studies [0.03%]
益肾化痰活血方和芸皮素改善多囊卵巢综合征蜕膜化功能障碍的临床与实验研究
Jing Wang,Lisha Li,Jing Zhou et al.
Jing Wang et al.
Polycystic ovary syndrome (PCOS) is a common gynecological endocrine disorder characterized by a complex pathogenesis and limited treatment options. Yishen Huatan and Huoxue decoction (YHHD), as a traditional Chinese Medicine formula, has s...
Bu-Shen-Ning-Xin decoction inhibits macrophage activation to ameliorate premature ovarian insufficiency-related osteoimmune disorder via FSH/FSHR pathway [0.03%]
补肾宁心汤通过抑制巨噬细胞活化改善卵巢早衰相关骨免疫异常的机制研究：垂体-卵巢轴功能状态的作用效应干预观察
Hongmei Sun,Qing Qi,Xinyao Pan et al.
Hongmei Sun et al.
Limited studies are associated with premature ovarian insufficiency (POI)-related osteoimmune disorder currently. Bu-Shen-Ning-Xin decoction (BSNXD) displayed a favorable role in treating postmenopausal osteoporosis. However, its impact on ...
Wenli Cao,Xiayan Fu,Haiyang Li et al.
Wenli Cao et al.
Tuberculosis is a chronic infectious disease caused by mycobacterium tuberculosis infection. In the world, tuberculosis is an important factor affecting women's reproductive health, which can cause reproductive tract anatomy abnormalities, ...
Metastasis to hypopharynx from epidermotropic metastatic malignant melanoma [0.03%]
皮肤恶性黑色素瘤转移性肿瘤累及下咽黏膜
Satoru Mizuhashi,Azusa Miyashita,Haruka Kuriyama et al.
Satoru Mizuhashi et al.
Previous reports proposed the concept and criteria of epidermotropic metastatic malignant melanoma (EMMM): (a) dermal involvement equal to or broader than the epidermal involvement, (b) atypical melanocytes within the dermis, (c) thinning o...
Rapamycin vs TORin-1 or Gleevec vs Nilotinib: Simple chemical evolution that converts PAK1-blockers to TOR-blockers or vice versa? [0.03%]
雷帕霉素对抗TORin-1或伊马替尼对抗尼洛替尼：将PAK1抑制剂转化为TOR抑制剂的简单化学进化反之亦然？
Hiroshi Maruta,Hong He
Hiroshi Maruta
Both PAK1 (RAC/CDC42-activating kinase 1) and TOR (Target of Rapamycin) are among the major oncogenic/ageing kinases. However, they play the opposite role in our immune system, namely immune system is suppressed by PAK1, while it requires T...
The prospects of automation in drug discovery research using silkworms [0.03%]
自动化技术在利用家蚕进行药物发现研究中的前景
Atsushi Miyashita,Masanobu Miyauchi,Fumiaki Tabuchi
Atsushi Miyashita
We have established several models of infectious diseases in silkworms to explore disease-causing mechanisms and identify new antimicrobial substances. These models involve injecting laboratory-cultured pathogens into silkworms and monitori...
Medication incidents associated with the provision of medication assistance by non-medical care staff in residential care facilities [0.03%]
非医疗护理人员提供药物帮助时与之相关的药物事件分析
Hayato Kizaki,Daisuke Yamamoto,Hideyuki Maki et al.
Hayato Kizaki et al.
The shift towards community-based care in Japan has led to increased medication assistance for older people by non-medical care staff. These staff members help take pre-packaged medications, apply patches, and administer eye drops. This stu...
A systematic review of the mechanistic actions of microRNAs within integrated traditional Chinese medicine and western medical treatment for endometriosis [0.03%]
微小核糖核酸在中西医结合治疗子宫内膜异位症的机制作用系统评价
Lisha Li,Yiqin Zhang,Jing Zhou et al.
Lisha Li et al.
Endometriosis (EM), also known as Zhengjia in traditional Chinese medicine, is a common disease that significantly impacts women's health. An integrated treatment approach combining traditional Chinese medicine (TCM) and western medicine ha...
Comparison of the physicochemical properties of branded and generic glucose-added maintenance hypotonic infusion fluids to assess the potential for phlebitis and incompatibility with other drugs [0.03%]
添加葡萄糖的维持性低张输液品牌的物理化学性质与通用药品的比较研究以评估其潜在的静脉炎风险及其与其他药物的配伍性问题
Sawako Takei,Soh Katsuyama,Yusuke Hori
Sawako Takei
In Japan, the switch from branded to generic infusion fluids has been promoted as a national policy. Recently, as generic products have been in short supply, the switch from generic to branded infusion fluids has increased. However, certain...