Padding the seat of a wheelchair reduces ischial pressure and improves sitting comfort [0.03%]
坐垫可减少轮椅使用者臀部压力并改善舒适度
Yoshiyuki Yoshikawa,Kiyo Sasaki,Kyoko Nagayoshi et al.
Yoshiyuki Yoshikawa et al.
In this study, we aimed to examine whether a wheelchair cushion placed directly atop a sling seat or deflection of the sling seat compensated by a pad along with the placement of a wheelchair cushion changed sitting pressure. Additionally, ...
Mitotic abnormalities and spindle assembly checkpoint inactivation in a cell model of Shwachman-Diamond syndrome with mutations in the Shwachman-Bodian-Diamond syndrome gene, 258+2T > C [0.03%]
Shwachman-Diamond综合征基因258+2T>C突变细胞模型中孟德尔异常和纺锤体组装检验点失活现象
Yukihiro Sera,Tsuneo Imanaka,Yusuke Iguchi et al.
Yukihiro Sera et al.
Hematologic abnormalities are the most common symptoms of Shwachman-Diamond syndrome (SDS). The causative gene for SDS is the Shwachman-Bodian-Diamond syndrome (SBDS) gene; however, the function of SBDS and pathogenesis of each condition in...
A stroke patient with persistently intermittent fever treated with gabapentin: A clinical case [0.03%]
一例加巴喷丁治疗持续间歇发热的卒中患者临床病例报告
Jingjie Huang,Bangqi Wu,Yupei Cheng et al.
Jingjie Huang et al.
Fever is one of the most common complications in stroke patients and can generally be classified as either infectious or non-infectious. Infectious fevers are commonly caused by pulmonary infections, urinary tract infections, and secondary ...
Effect of switching from dulaglutide to tirzepatide on blood glucose and renal function [0.03%]
德谷胰岛素切换为 tirzepatide 对血糖和肾功能的影响
Atsushi Ishimura,Hiroyoshi Kumakura
Atsushi Ishimura
The case reports a woman in her 70s, with type 2 diabetes and chronic kidney disease in G4 stage. The patient had elevated HbA1c, and she was switched from linagliptin, a dipeptidyl peptidase 4 inhibitor, to dulaglutide, a glucagon-like pep...
Panax notoginseng root extract induces nuclear translocation of CRTC1 and Bdnf mRNA expression in cortical neurons [0.03%]
三七总皂苷诱导皮层神经元CRTC1核转位及BDNF表达的作用机制研究
Shunsuke Shimizu,Aoi Nakano,Daisuke Ihara et al.
Shunsuke Shimizu et al.
Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is deeply involved in the development and higher function of the nervous system, including learning and memory. By contrast, a reduction in BDNF levels is associ...
Histopathological analysis of filament formation of Nocardia farcinica in a silkworm infection model [0.03%]
家蚕感染模型中诺卡菌丝形成的组织病理分析
Koki Iwata,Mizuho Sato,Shoko Yoshida et al.
Koki Iwata et al.
The silkworm Nocardia infection model has been established as a useful animal model for screening the pathogenicity of Nocardia and evaluating the therapeutic effects of antimicrobial agents against Nocardia infection. No histopathological ...
General selection criteria for safety and patient benefit [XⅢ]: Comparing the formulation characteristics of brand-name and generic bifonazole creams [0.03%]
盐酸比芬扎醇软膏仿制品的质量和疗效一致性评估——比较品牌商和仿制样品的制剂属性（III）
Ken-Ichi Shimokawa,Natsuki Ichimura,Marika Nozawa et al.
Ken-Ichi Shimokawa et al.
A comparative evaluation of the brand-name drug Mycospor and six generic drugs (IWAKI, Bifonol, F, YD, Sawai, and TEVA), all comprising a cream formulation containing the antifungal drug bifonazole, was performed based on physicochemical me...
Comparative Study
Drug discoveries & therapeutics. 2024 Nov 15;18(5):277-282. DOI:10.5582/ddt.2024.01068 2024
Astaxanthin compound nutrient improved insulin resistance, hormone levels, embryo quality and pregnancy outcomes in polycystic ovary syndrome patients undergoing in vitro fertilization/intracytoplasmic sperm injection [0.03%]
虾青素复合营养素可改善多囊卵巢综合征患者体外受精/卵胞浆内单精子注射的胰岛素抵抗、激素水平、胚胎质量和妊娠结局
Xiayan Fu,Wenli Cao,Feijun Ye et al.
Xiayan Fu et al.
This study aimed to evaluate the effect of astaxanthin compound nutrient (ACN) complementary therapy on pregnancy outcomes in polycystic ovary syndrome (PCOS) patients undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/...
Electrolytic-reduction ion water protects keratinocytes from hydrogen peroxide through radical scavenging activity and induction of AQP3 expression [0.03%]
电解还原离子水通过清除活性氧和诱导AQP3表达保护角质形成细胞免受过氧化氢损伤
Hiroyuki Yamamoto,Tokuko Takajo,Ami Tsuchibuchi et al.
Hiroyuki Yamamoto et al.
Skin exposed to ultraviolet light produces hydrogen peroxide (H2O2) and reactive oxygen species (ROS) that cause protein denaturation and other disorders. We investigated whether electrolytic-reduction ion water (ERI), which has reducing pr...
Differences in fluidity and viscosity of brand-name and generic injectable ointment [0.03%]
品牌药和仿制注射软膏的流变学差异
Atsushi Ishimura,Chiaki Ogawa,Megumi Yatabe et al.
Atsushi Ishimura et al.
Generic medications contain the identical active ingredient in the same concentration as their branded counterparts and are administered in the same manner, aiming to deliver comparable efficacy, dosage, and clinical outcomes. Nevertheless,...
Comparative Study
Drug discoveries & therapeutics. 2024 Sep 19;18(4):265-268. DOI:10.5582/ddt.2024.01051 2024