A circadian rhythm-restricted diet regulates autophagy to improve cognitive function and prolong lifespan [0.03%]
昼夜节律限制饮食通过调节自噬来改善认知功能和延长寿命
Xiqi Hu,Jun Peng,Wei Tang et al.
Xiqi Hu et al.
Diet and circadian rhythms have been found to have a profound impact on health, disease, and aging. Skipping breakfast, eating late, and overeating have adverse effects on the body's metabolism and increase the risk of cardiovascular and me...
Ya-Nan Ma,Xuemei Jiang,Wei Tang et al.
Ya-Nan Ma et al.
Studies have found that intermittent fasting (IF) can prevent diabetes, cancer, heart disease, and neuropathy, while in humans it has helped to alleviate metabolic syndrome, asthma, rheumatoid arthritis, Alzheimer's disease, and many other ...
Zhipeng Sun,Bing Liu,Bin Shu et al.
Zhipeng Sun et al.
Solitary intrahepatic biliary cyst (SIBC) is a rare disease, and due to the lack of adequate understanding of it, SIBC is often misdiagnosed as simple liver cyst (SLC), which in turn affects the therapeutic effect. In order to arouse more a...
Impact of sarcopenia on S1 adjuvant chemotherapy and prognosis in pancreatic cancer patients [0.03%]
肌少症对胰腺癌术后辅助化疗及预后影响的研究
Kumi Takagi,Yosuke Inoue,Atsushi Oba et al.
Kumi Takagi et al.
Although the importance of adjuvant chemotherapy (AC) has been recognized in pancreatic cancer (PC) patients, there are few studies to address the underlying mechanisms of failure to complete AC. This study aims to investigate the relations...
Xiqi Hu,Yanan Ma,Xuemei Jiang et al.
Xiqi Hu et al.
With the rapid increase in global aging, the prevalence of frailty is increasing and frailty has emerged as an emerging public health burden. Frail elderly patients suffer from reduced homeostatic reserve capacity, which is associated with ...
Kazuhiko Kotani
Kazuhiko Kotani
Along with the transition to depopulation and an aging society in Japan, the modification of community medicine and its related systems is required. With this in mind, the Japanese government has recently advocated two major plans: 'Communi...
Geriatric syndromes, chronic inflammation, and advances in the management of frailty: A review with new insights [0.03%]
老年综合征、慢性炎症和脆弱管理的进展：综述及新见解
Niuniu Li,Gaolin Liu,Hong Gao et al.
Niuniu Li et al.
As people age, geriatric syndromes characterized by frailty significantly impact both clinical practice and public health. Aging weakens people's immune functions, leading to chronic low-grade inflammation that ultimately contributes to the...
Tetsuya Asakawa,Takashi Karako
Tetsuya Asakawa
By far, there is no general consensus concerning the definition of frailty even though it may be a global public health concern with aging of the population. It is regarded as a pathophysiological state before development of a severe illnes...
Healthy aging, early screening, and interventions for frailty in the elderly [0.03%]
老年人健康老龄化、早期筛查和衰弱干预措施
Yi Deng,Keming Zhang,Jiali Zhu et al.
Yi Deng et al.
With the intensification of population aging worldwide, the health problems of the elderly have become a particular concern. Functional disability is a prominent problem in the aging of this population, resulting in the decreased quality of...
Alzheimer's disease with frailty: Prevalence, screening, assessment, intervention strategies and challenges [0.03%]
痴呆伴衰弱综合征的筛查、评估、干预策略及挑战
Yi Deng,Haiyin Wang,Kaicheng Gu et al.
Yi Deng et al.
Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions worldwide and is expected to surge in prevalence due to aging populations. Frailty, characterized by muscle function decline, becomes more prevalent with age, im...