Stem cell-derived extracellular vesicles for rare diseases: A clinical‑bottleneck‑to‑mechanism framework for translation [0.03%]
基于干细胞的外泌体在罕见病中的应用：从临床瓶颈到机制框架的转化医学研究
Yue Han,Nuo Chen,Peipei Song et al.
Yue Han et al.
Rare diseases impose a disproportionate clinical burden, and yet therapeutic progress is hindered by small cohorts, biological heterogeneity, and limited disease-specific options. Stem cell-derived extracellular vesicles (EVs), and especial...
Brain-computer interfaces: A lifeline for paralysis or a Pandora's box for humanity? [0.03%]
脑机接口：解锁瘫痪患者的“生命线”还是打开人类的“潘多拉魔盒”?
Tetsuya Asakawa
Tetsuya Asakawa
Recent advances in computerized technologies, neuroscience, and materials and engineering have transformed brain‑computer interfaces (BCIs) from conventional unidirectional signal recording systems (brain-to-device) to bidirectional closed...
Clinical translation and accessibility of brain-computer interfaces: From technology development to clinical application [0.03%]
脑机接口的临床转化和可及性：从技术开发到临床应用
Hui Sun,Ru Wang,Kenji Karako et al.
Hui Sun et al.
Brain-computer interface (BCI) technology establishes a direct communication pathway between neural activity and external devices. Driven by advances in neuroscience, artificial intelligence (AI), neural signal acquisition, decoding algorit...
Early post-reperfusion neutrophil dynamics after liver transplantation: Association with graft size [0.03%]
肝移植术后早期灌注中性粒细胞动态变化与移植物大小的关系
Michiko Ushio,Gaku Kawamura,Takakazu Yuki et al.
Michiko Ushio et al.
Patients with end-stage liver disease often exhibit impaired neutrophil function and have an elevated risk for perioperative infections. Liver transplantation (LT) restores hepatic function; however, perioperative neutrophil dynamics and th...
Moving long-term care insurance upstream: A geriatric-syndrome-oriented framework for healthy aging in China [0.03%]
面向健康的中国老年综合征长期照护保险框架研究
Xiqi Hu,Xiaoli Wu,Ya-Nan Ma et al.
Xiqi Hu et al.
Long-term care insurance (LTCI) is commonly understood as a social insurance mechanism that compensates care-related costs after disability has occurred. This compensation function remains essential, but it is insufficient in the context of...
From pilot programs to nationwide implementation: Reform of China's long-term care insurance in an aging society [0.03%]
从试点到全面铺开：老龄化社会中的长期护理保险制度改革
Ren Chen,Wei Tang
Ren Chen
China is experiencing rapid population aging and a growing burden of disability, creating urgent demand for sustainable long-term care systems. In response, China has progressively developed a long-term care insurance system since the launc...
Imported Ebola as a stress test of hospital resilience in an era of global connectivity [0.03%]
进口埃博拉病毒作为全球互联时代的医院压力测试及应对策略
Yue Ma,Yifan Xu,Lu Tan et al.
Yue Ma et al.
In May 2026, an outbreak of Ebola virus disease caused by Bundibugyo ebolavirus emerged in the Democratic Republic of the Congo and spread to Uganda, prompting a WHO Public Health Emergency of International Concern. With no approved vaccine...
Clinically constrained optical design of a high-numerical aperture miniature immersion objective for probe-based confocal laser endomicroscopy [0.03%]
临床约束的高数值孔径微型浸入物镜光学设计用于探针共焦激光内窥显微镜
Yu Feng,Jiali Chen,Yong Wan et al.
Yu Feng et al.
Confocal laser endomicroscopy (CLE) is a critical modality for the early, minimally invasive diagnosis of intraluminal diseases. However, its clinical translation is constrained by the inherent optical-mechanical trade-offs between numerica...
Revisiting long-standing biological questions through evolving technologies [0.03%]
通过不断发展的技术重新审视经典的生物学问题
John J Rossi
John J Rossi
Advances in biological sciences and technology have continuously reshaped the questions that researchers are able to address. Over the past several decades, developments in DNA sequencing, mass spectrometry, genome analysis, and omics techn...
Gene expression profiling of the L4-stage nematode Caenorhabditis elegans following ethanol exposure [0.03%]
乙醇暴露后秀丽杆线虫L4期基因表达谱分析
Masaki Miyazawa,Ching Ouyang,Mariko Sezaki et al.
Masaki Miyazawa et al.
Previous studies have suggested that low to moderate alcohol exposure can extend Caenorhabditis elegans (C. elegans) lifespan, but early molecular mechanisms linking ethanol exposure to longevity have not been fully characterized. Here, we ...