[Respiratory Rehabilitation in Neuromuscular Diseases: Emphasis on Lung Volume Recruitment and Mechanical Insufflation-Exsufflation] [0.03%]
神经肌肉疾病呼吸康复的肺容量 recruit 及机械 insufflation-exsufflation 治疗强调
Keisuke Yorimoto
Keisuke Yorimoto
Respiratory impairment in neuromuscular diseases is primarily characterized by restrictive ventilatory dysfunction caused by progressive respiratory muscle weakness, which significantly affects survival and quality of life. This article out...
Takayo Chuma
Takayo Chuma
Neurological intractable diseases are progressive, and as the disease advances, symptoms can include not only motor impairments but also autonomic nervous system disorders and higher brain dysfunction, with a wide range of pathologies. Pati...
[Genetic Counseling and Interprofessional Collaboration in Intractable Diseases] [0.03%]
难治性疾病的遗传咨询与跨专业合作
Tomoko Sekiya
Tomoko Sekiya
In recent years, with the advancement of genetic medicine for intractable diseases, opportunities for genetic testing and diagnosis have increased. Because genetic information is shared among blood relatives, cases in which a patient's diag...
[Current Status and Challenges of Emerging Genetic Medicine for Rare Diseases: Focus on PGT-M] [0.03%]
[罕见病新兴遗传学医学的现状与挑战：以胚胎植入前遗传学检测为主角]
Aiko Sasaki
Aiko Sasaki
Many monogenic disorders do not yet have sufficiently established curative treatments, requiring affected individuals and their families to engage in ongoing decision-making regarding pregnancy and long-term life planning. In reproductive a...
[Characteristics of Clinical Ethical Issues in Neurodegenerative Diseases and Shared Decision Making] [0.03%]
神经变性疾病临床伦理问题的特点及共决医学模式的应对措施
Makoto Sugiura
Makoto Sugiura
In neurological care, ethical issues often arise because of cognitive decline and prognostic uncertainty. These conflicts typically stem from competing values among the four principles of biomedical ethics. To address these issues, practici...
[New Era in Neurodegenerative Disease: Therapeutic Advances and Social and Ethical Challenges] [0.03%]
神经退行性疾病的新时代：治疗进展与社会伦理挑战
Makoto Urushitani
Makoto Urushitani
Recent advances in molecular genetics and cellular modeling have begun to transform the landscape of neurodegenerative diseases, long regarded as "incurable and poorly understood." The identification of causative genes and disease-associate...
[Re-evaluating ALS Medical Care in Japan: An International Comparison of Japan, Europe, the United States, and Canada-Insights from Mechanical Ventilation, Support for Social Participation, End-of-Life Care Options, Approved Drugs, and Precision Medicine] [0.03%]
从国际比较看日本ALS医疗的重新评估：以机械通气、社会参与支援、终末期照护选项、获批药物及精准医疗等视角探讨日本、欧洲、美国和加拿大的情况得的见解
Michiya Ito
Michiya Ito
Amyotrophic lateral sclerosis (ALS) care in Japan should be re-evaluated not simply as a matter of clinical choice but as a function of the public support system structure. In Japan, care is distinguished by a publicly funded model that sup...
Tetsuo Komori
Tetsuo Komori
Support measures for intractable diseases in Japan began in 1972 and, since 2015, have been implemented under the Act on Medical Care for Patients with Intractable Diseases. This article provides an overview of key activities and achievemen...
[Brain Amoebiasis] [0.03%]
[脑阿米巴病]
Hajime Miyata,Kenji Yagita
Hajime Miyata
Amoebic infections of the brain can cause brain abscesses and meningoencephalitis. Brain abscess is a rare form of extraintestinal amoebiasis caused by hematogenous spread from intestinal infection with Entamoeba histolytica, which occurs t...
[Cerebral Echinococcosis] [0.03%]
[脑包虫病]
Tomohiro Uemura,Takashi Kanda
Tomohiro Uemura
Cerebral echinococcosis is a potentially fatal central nervous system infection caused by Echinococcus tapeworms, such as E. multilocularis and E. granulosus. It often metastasizes from lesions in other organs, including the liver, and rare...