Nanoliposome mediated co-delivery of amoxicillin and tazobactam remediate intracellular infection by a multidrug-resistant Salmonella enterica serovar Typhimurium [0.03%]
纳米脂质体介导的阿莫西林和他唑巴坦联合递送可改善多药耐药鼠伤寒沙门氏菌的胞内感染
Trisha Sackey,Unnikrishnan Kannan,Satwik Majumder et al.
Trisha Sackey et al.
Multidrug-resistant (MDR) Salmonella enterica serovar Typhimurium (S. Typhimurium) poses a growing threat to food safety and animal health, particularly in the swine industry. In this study, we characterized a highly resistant ST strain iso...
Streptomyces lemnae sp. nov., a novel actinomycete isolated from Lemna aequinoctialis [0.03%]
解旋 Lemna aequinoctialis 的新型放线菌链霉菌 Lemnae 菌株 Nov.
Peeraya Boonchu,Waranya Butdee,Chadarat Na Phatthalung et al.
Peeraya Boonchu et al.
A novel Streptomyces species, designated strain DW26H14T, was isolated from duckweed (Lemna aequinoctialis) and characterized using a polyphasic taxonomic approach. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strai...
Yi Tang
Yi Tang
Isolation of N-acetylallosaminylallosamidin, a new pseudotetrasaccharide allosamidin congener [0.03%]
N-乙酰半乳糖胺半乳糖胺素的分离纯化这是一种新的假四糖半乳糖胺素同类物
Shohei Sakuda,Kenichi Uchida,Noriko Hakoshima et al.
Shohei Sakuda et al.
Allosamidin is a metabolite produced by Streptomyces species, known for its inhibitory activity against family 18 chitinases. All known natural congeners of allosamidin are pseudotrisaccharides featuring a cyclopentane moiety fused with an ...
Indigomycin, a new pyridinetrione from Streptomyces albus J1074 harboring the indigoidine biosynthetic gene cluster [0.03%]
产色斑素基因簇的链霉菌J1074产生的新型吡啶三酮抗生素靛霉素
Jinfen Yuan,Tengfei Zhao,Zengguang Zhang et al.
Jinfen Yuan et al.
Heterologous expression of the indigoidine biosynthetic gene cluster from Streptomyces laurentii ATCC 31255 in Streptomyces albus J1074 resulted in the production of the known blue pigment indigoidine, along with a structurally novel pyridi...
Repurposing Tirazone as an effective quorum-sensing inhibitor against Pseudomonas aeruginosa virulence and biofilm formation [0.03%]
特拉唑重定位为有效抑制绿脓杆菌毒力和生物被膜形成的群体感应抑制剂
Mengna Feng,Xiaoyu Wu,Xin Hu et al.
Mengna Feng et al.
Antibiotic resistance has emerged as a critical global public health challenge. Quorum sensing (QS), a density-dependent regulatory mechanism, plays a pivotal role in bacterial pathogenesis by coordinating virulence factor expression, makin...
Meropenem, Ceftazidime, and Polymyxin B combination therapy: a novel approach to combat antimicrobial resistance in MDR, XDR and PDR Escherichia coli [0.03%]
美罗培南、头孢他啶和多粘菌素B联合治疗：对抗MDR、XDR和PDR肠杆菌的新方法
Siddhi A Darji,Avani Raulji,Axita Patel et al.
Siddhi A Darji et al.
Antimicrobial resistance (AMR) in Escherichia coli (E.coli) poses a significant global threat to public health due to increasing resistance against antibiotics. This study explored a novel combination therapy by investigating the synergisti...
Synergy evaluation of cefepime/enmetazobactam in combination with novel β-lactam/β-lactamase inhibitor combinations (βL/βLICs) against Klebsiella pneumoniae carrying different blaKPC variants [0.03%]
头孢吡肟/恩美培南与新型β-内酰胺酶抑制剂复合制剂联合对产不同blaKPC基因型肺炎克雷伯菌的协同作用评价
Carlo Tascini,Giulia Zocche,Paolo Gaibani
Carlo Tascini
Streptomyces aurantiaciflavus sp. nov., a novel actinomycete isolated from rhizosphere soil with antifungal activity and plant growth-promoting ability [0.03%]
产红橙黄色系链霉菌新种aurantiaciflavus及其抗菌和促生特性
Jiaxin Jin,Xue Zhao,Muxi Zhang et al.
Jiaxin Jin et al.
A novel actinobacterial strain NEAU-NA10T showing antifungal activity and plant growth-promoting ability was isolated from the rhizosphere soil of strawberry seedlings collected from Ya'an City, Sichuan Province, China (28°51' N, 101°56' ...
Marinapyrones A and B, new antioxidative α-pyrones produced by soybean rhizosphere-derived actinomycete strain W21-0103 [0.03%]
来源于大豆根系菌株W21-0103链霉菌的新抗氧化α-吡喃化合物marinapyrone A和B
Satoru Shigeno,Yuki Onishi,Yohei Nishikawa et al.
Satoru Shigeno et al.
Two new α-pyrone compounds designated marinapyrones A (1) and B (2) were isolated along with the known related compound micropyrone B (3) from the culture broth of rhizosphere-derived actinomycete strain W21-0103. The structures of 1 and 2...