Amamine, an isoquinoline alkaloid from the Kitasatospora sp. HGTA304 [0.03%]
来源于HGTA304菌株的kitasinoline生物碱胺胺胺amineamine
Teppei Kawahara,Marin Ueda,Naoki Kishimoto et al.
Teppei Kawahara et al.
Amamine (1), a new isoquinoline alkaloid, was isolated from the culture extract of an actinomycete Kitasatospora sp. HGTA304. The structure of 1 was determined by NMR and MS analyses in combination with UV data. Compound 1 displayed α-gluc...
Ramses Gallegos-Monterrosa,Rodrigo Orozco Mendiola,Yoselin Nuñez et al.
Ramses Gallegos-Monterrosa et al.
Currently, antibiotic-resistant bacteria represent a serious threat to public health worldwide. Biofilm formation potentiates both virulence and antibiotic resistance of bacteria. Therefore, the discovery of new antibacterial and antibiofil...
Isolation of two new stereochemical variants of streptophenazine by cocultivation of Streptomyces NIIST-D31, Streptomyces NIIST-D47, and Streptomyces NIIST-D63 strains in 3C2 combinations [0.03%]
通过三菌株组合培养分离链霉菌NIIST-D31、-D47和-D63的两种新型几何异构体抗生素streptophenazine
D K Induja,A R S Jesmina,Manu M Joseph et al.
D K Induja et al.
Cocultivation of combinations of Streptomyces species isolated from the same soil was explored to isolate novel secondary metabolites. Recently, we reported the isolation of a novel vicinal diepoxide of alloaureothin along with three carbox...
Constitutive and high gene expression in the diaminopimelate pathway accelerates ε-poly-L-lysine production in Streptomyces albulus [0.03%]
谷氨酸族路径的组成型及高表达加速链霉菌素白酶素聚ε- L-赖氨酸的产生
Fumihito Hasebe,Kazuya Adachi,Kazuya Yamanaka et al.
Fumihito Hasebe et al.
Streptomyces albulus NBRC14147 produces a homopoly(amino acid), ε-poly-L-lysine (ε-PL). Due to its antibiotic activity, thermostability, biodegradability, and non-toxicity to humans, ε-PL is used as a food preservative. In this study, ho...
Impact of soil supplemented with pig manure on the abundance of antibiotic resistant bacteria and their associated genes [0.03%]
添加猪粪的土壤中抗生素抗性细菌及其相关基因丰度的影响
Adebayonle Akinduro,Chisom Iyunoluwa Onyekwelu,Tomisin Oyelumade et al.
Adebayonle Akinduro et al.
This study was conducted to evaluate the abundance of antibiotic resistant bacteria and their resistance genes from agriculture soil supplemented with pig manure. Uncultivable soil sample was supplemented with pig manure samples under micro...
Mark S Butler,Ian R Henderson,Robert J Capon et al.
Mark S Butler et al.
The need for new antibacterial drugs to treat the increasing global prevalence of drug-resistant bacterial infections has clearly attracted global attention, with a range of existing and upcoming funding, policy, and legislative initiatives...
Avidumicin, a novel cyclic bacteriocin, produced by Cutibacterium avidum shows anti-Cutibacterium acnes activity [0.03%]
一种新型环状细菌素Avidumicin由Cutibacterium avidum产生并表现出抗Cutibacterium acnes活性
Juri Koizumi,Keisuke Nakase,Norihisa Noguchi et al.
Juri Koizumi et al.
The prevalence of antimicrobial-resistant Cutibacterium acnes in acne patients has increased owing to inappropriate antimicrobial use. Commensal skin bacteria may play an important role in maintaining the balance of the skin microbiome by p...
Rubensteroid A, a new steroid with antibacterial activity from Penicillium rubens AS-130 [0.03%]
来自曲霉AS-130的具有抗菌活性的新倍半萜甾醇rubensteroid A
Zhen Ying,Xiao-Ming Li,Bin-Gui Wang et al.
Zhen Ying et al.
A new steroid with strong antibacterial activity, rubensteroid A (1), along with its decarboxylic analogue, solitumergosterol A (2), were isolated and identified from the Magellan Seamount-derived fungus Penicillium rubens AS-130. The struc...
Correction: p-Terphenyl glucosides from the culture broth of Phlebiopsis castanea [0.03%]
纠正：Phlebiopsis castanea 文化滤液中的对位三苯基葡萄糖苷
Dae-Cheol Choi,Dae-Won Ki,Ji-Yul Kim et al.
Dae-Cheol Choi et al.
Published Erratum
The Journal of antibiotics. 2023 Jul;76(7):430. DOI:10.1038/s41429-023-00630-1 2023
In vitro activity of ceftazidime/avibactam, imipenem/relebactam and meropenem/vaborbactam alone or in combination with polymyxin B against carbapenem resistant Acinetobacter baumannii [0.03%]
头孢他啶/阿维巴坦、雷利巴坦和美罗培南/维泊酮单用或与多黏菌素B联合对碳青霉烯耐药的鲍曼不动杆菌的体外活性研究
Rongxin Liang,Dongxing Wang,Mingjin Hu et al.
Rongxin Liang et al.
Nosocomial infection caused by Carbapenem-Resistant Acinetobacter baumannii (CR-A. baumannii) has become a challenge in clinical practice. Acting as the last resort antibacterial agents for the treatment of CR-A. baumannii infection, polymy...