Aflatoxin exposure and health impacts: global burden and advances in detection technologies [0.03%]
黄曲霉毒素暴露与健康影响：全球疾病负担及检测技术进展
Gudisa Bereda
Gudisa Bereda
Background and aims: Aflatoxins are food contaminants that cause exposure and adverse health effects and are detected using modern analytical methods. This review summarizes global aflatoxin exposure levels, exposure rout...
Application of chimeric mice with human hepatocytes for the evaluation of metabolically activated genotoxic substances [0.03%]
人源肝细胞嵌合小鼠在代谢活化致突变物评价中的应用研究
Mayu Fujikawa,Ryoko Matsuyama,Chihiro Yamasaki et al.
Mayu Fujikawa et al.
Background: The in vivo micronucleus (MN) assay is used for evaluation of chromosomal aberration induced by chemicals, and the liver MN assay can detect genotoxic compounds which require metabolic activation to induce mic...
Mechanistic investigation of flavonoid-mediated inhibition of N-methyl-N-nitrosourea-induced mutagenicity via noncovalent DNA binding [0.03%]
通过非共价DNA结合研究黄酮类化合物介导的N-甲基-N'-硝脲诱发突变性的抑制机制
Chisato Matsuoka,Nao Takatama,Takuya Muraoka et al.
Chisato Matsuoka et al.
Background: Previous research using the Ames assay showed that licoricidin (LCD) and isoliquiritigenin (ILTG) can block mutations caused by N-methyl-N-nitrosourea (MNU) in Salmonella typhimurium (S. typhimurium) TA1535. W...
A PUFA-rich diet increases endogenous genotoxic stress and mitochondrial DNA damage in mice [0.03%]
富含PUFA的饮食可通过增加内源性致突变压力导致小鼠线粒体DNA损伤
Masatomi Shimizu,Ayako Daizo,Kenichi Kawada et al.
Masatomi Shimizu et al.
Background: Substitution of dietary saturated fat with seed oils highly enriched in n-6 polyunsaturated fatty acids (PUFAs) has been advocated as healthy strategy to offset elevated cholesterol levels. However, both n-6 a...
A report on the international conference on environmental mutagenesis in relation to human health held during the annual meeting of the Environmental Mutagen Society of India, January 29-31, 2026 [0.03%]
关于环境诱变与人类健康国际会议的报告：印度环境诱变学会年度会议（2026年1月29日至31日）
Bani Bandana Ganguly
Bani Bandana Ganguly
The 48th Annual Meeting and International Conference of the Environmental Mutagen Society of India (EMSI) on 'Environmental Mutagenesis & Epigenomics in Relation to Human Health' was held at Jamshedpur Co-Operative College, in association w...
Potential for Computational Genotoxicity: A Report on Symposium 3 of the 53rd Annual Meeting of the Japanese Environmental Mutagen and Genome Society (JEMS), 2024 [0.03%]
计算基因毒性的潜力：日本环境诱变剂和基因组学会（JEMS）第53届年会第3 symposium 报告
Naoki Koyama,Ayako Furuhama,Naomi L Kruhlak et al.
Naoki Koyama et al.
Symposium 3 of the 53rd Annual Meeting of the Japanese Environmental Mutagen and Genome Society (JEMS), entitled "Potential for Computational Genotoxicity," was held at Shujitsu University, Okayama, Japan, on December 8, 2024. The symposium...
A genome-wide interaction study of thyroid-stimulating hormone levels and particulate matter exposure among Koreans [0.03%]
韩国人促甲状腺激素水平基因组-环境互作的全基因组研究
Young Jun Park,Hyun-Jin Kim,Ho-Young Son et al.
Young Jun Park et al.
In vivo mammalian micronucleus test in mice confirms lack of genotoxic potential of a protein-rich powder derived from Xanthobacter sp. SoF1 [0.03%]
源于Xanthobacter.sp.SoF1的蛋白质粉对哺乳动物的小鼠微核试验未表现出遗传毒性
Bean Choi,John R Endres,Amy Clewell et al.
Bean Choi et al.
Correction: Development of a DNA damage assay system using stable human hepatocytes [0.03%]
订正：利用稳定的人类肝细胞建立DNA损伤检测体系
Masayuki Mishima,Kazuki Izawa,Masataka Tsuda et al.
Masayuki Mishima et al.
Ellagic acid is associated with reduced pancreatic carcinogenesis and modulation of the IL-6/STAT3 pathway [0.03%]
ellagic酸与胰腺癌变减少及IL-6/STAT3通路调节相关
Hiroyuki Kato,Aya Naiki-Ito,Masayuki Komura et al.
Hiroyuki Kato et al.
Background: The 5-year survival of pancreatic ductal adenocarcinoma (PDAC) remains about 10% despite therapeutic advances, underscoring the need for effective preventive and early intervention strategies. Ellagic acid (EA...