Exercise preconditioning initiates late cardioprotection against isoproterenol-induced myocardial injury in rats independent of protein kinase C [0.03%]
运动预适应通过独立于蛋白激酶C的机制诱导异丙肾上腺素致大鼠心肌损伤的迟发性心保护作用
Yu-Jun Shen,Shan-Shan Pan,Tao Zhuang et al.
Yu-Jun Shen et al.
The objective of this study was to investigate the late cardioprotective effect of exercise preconditioning (EP) on isoproterenol (ISO)-induced myocardial injury in rats and the role of protein kinase C (PKC) in EP. Rats were injected with ...
The effects of β-adrenergic stimulation and exercise on NR4A3 protein expression in rat skeletal muscle [0.03%]
β肾上腺素受体刺激和运动对大鼠骨骼肌NR4A3蛋白表达的影响
Emi Kawasaki,Fumi Hokari,Maiko Sasaki et al.
Emi Kawasaki et al.
β-Adrenergic stimulation and exercise up-regulate the mRNA expression of nuclear receptor NR4A3, which is involved in the regulation of glucose and fatty acid utilization genes in skeletal muscle. The objective of our study was to examine ...
Contribution of nitric oxide to cerebral blood flow regulation under hypoxia in rats [0.03%]
硝酸氧化物对缺氧大鼠脑血流调节的贡献
Hiroyuki Takuwa,Tetsuya Matsuura,Rumiana Bakalova et al.
Hiroyuki Takuwa et al.
This study was designed to clarify whether nitric oxide (NO) participates in the regulation of local cerebral blood flow (CBF) during hypoxia (inhalation of 15% O(2) in N(2)). The CBF response to hind-paw stimulation (evoked CBF) of Sprague...
KB-R7943 inhibits Na+-dependent Mg2+ efflux in rat ventricular myocytes [0.03%]
KB-R7943抑制大鼠心室肌细胞Na+-依赖性Mg2+外流
Michiko Tashiro,Hana Inoue,Masato Konishi
Michiko Tashiro
Na(+)-dependent Mg(2+) efflux activity was studied with the fluorescent Mg(2+) indicator furaptra in the presence of various potential antagonists known to inhibit other transporters and channels. Among the compounds tested, KB-R7943, an in...
Hypothalamic SOCS-3 expression and the effect of intracerebroventricular angiotensin II injection on water intake and renal sodium handling in SHR [0.03%]
大鼠下丘脑SOCS-3表达及其脑室内注射血管紧张素II对水摄入和肾脏钠处理的影响研究
Adriana Zapparoli,Vivian Calegari,Lício Augusto Velloso et al.
Adriana Zapparoli et al.
In rats, the acute central dipsogenic and natriuretic action of angiotensin II (AngII) seems to be independent of the hemodynamic effects of the peptide; however, in genetically hypertensive models, this relationship has not yet been invest...
Control of ionic selectivity by a pore helix residue in the Kv1.2 channel [0.03%]
Kv1.2通道中控制离子选择性的孔螺旋残基
Chia-Chia Chao,Chieh-Chen Huang,Chang-Shin Kuo et al.
Chia-Chia Chao et al.
Interaction between the selectivity filter and the adjacent pore helix of voltage-gated K(+) (Kv) channels controls pore stability during K(+) conduction. Kv channels, having their selectivity filter destabilized during depolarization, are ...
Both skeletonized and pedicled internal thoracic arteries supply adequate graft flow after coronary artery bypass grafting even during intense sympathoexcitation [0.03%]
经冠状动脉旁路移植术后即使在交感神经兴奋强烈时期内乳动脉无论是否骨化都能提供充足的搭桥血流
Dai Une,Shuji Shimizu,Atsunori Kamiya et al.
Dai Une et al.
The internal thoracic artery (ITA) is harvested by either the pedicled or the skeletonized technique in coronary artery bypass grafting (CABG), with no clear advantage of one technique over the other. We compared graft flow between the pedi...
Correlation between plasma and saliva adrenocortical hormones in response to submaximal exercise [0.03%]
亚极量运动时血浆和唾液肾上腺皮质激素的相关关系
R Thomasson,A Baillot,L Jollin et al.
R Thomasson et al.
This study examined the relationships between plasma and saliva adrenocortical hormones in response to long-duration submaximal exercise. In nine healthy, physically active, female volunteers, blood and saliva samples were taken at rest and...
Vasoactive intestinal polypeptide relaxes isolated rat pulmonary artery rings through two distinct mechanisms [0.03%]
血管活性肠肽通过两种不同的机制松弛大鼠肺动脉环
Shuang Zhang,Yun Liu,Shouli Guo et al.
Shuang Zhang et al.
Vasoactive intestinal polypeptide (VIP), an endogenous neuropeptide normally present in lungs and other organs, relaxes pulmonary arteries (PAs) in different species, whereas the underlying mechanisms are still not fully understood. The aim...
Hypoxia suppresses Kv 2.1 channel expression through endogenous 15-hydroxyeicosatetraenoic acid in rat pulmonary artery [0.03%]
缺氧通过内源性15-羟基二十碳四烯酸抑制大鼠肺动脉Kv 2.1通道表达
Lei Guo,Zhaoping Qiu,Lei Zhang et al.
Lei Guo et al.
We have previously reported that hypoxia activates lung 15-lipoxygenase (15-LOX), which catalyzes arachidonic acid to produce 15-HETE, leading to constriction of neonatal rabbit pulmonary arteries. Hypoxia suppresses Kv2.1 channel expressio...