Comparison of the effects of continuous and pulsatile left ventricular-assist devices on ventricular unloading using a cardiac electromechanics model [0.03%]
基于心脏电力学模型比较连续流和脉动流左心室辅助装置对心室卸载的影响
Ki Moo Lim,Jason Constantino,Viatcheslav Gurev et al.
Ki Moo Lim et al.
Left ventricular-assist devices (LVADs) are used to supply blood to the body of patients with heart failure. Pressure unloading is greater for counter-pulsating LVADs than for continuous LVADs. However, several clinical trials have demonstr...
Calcium imaging of neuronal activity in the most rostral parafacial respiratory group of the newborn rat [0.03%]
新生大鼠最前端的外侧延髓呼吸神经元群体的钙成像活动观测
Hiroshi Onimaru,Mathias Dutschmann
Hiroshi Onimaru
The parafacial respiratory group (pFRG) is thought to be involved in respiratory rhythm generation in neonates. This subgroup expresses the transcription factor, Phox2b, and contains intrinsically CO(2) sensitive neurons. Calcium imaging ha...
The effect of high-intensity intermittent swimming on post-exercise glycogen supercompensation in rat skeletal muscle [0.03%]
高强度间歇游泳对大鼠骨骼肌糖原超补偿的影响
Akiko Sano,Keiichi Koshinaka,Natsuki Abe et al.
Akiko Sano et al.
A single bout of prolonged endurance exercise stimulates glucose transport in skeletal muscles, leading to post-exercise muscle glycogen supercompensation if sufficient carbohydrate is provided after the cessation of exercise. Although we r...
Interferon-beta, but not tumor necrosis factor-alpha, production in response to poly I:C is maintained despite exhaustive exercise in mice [0.03%]
干扰素-β而非肿瘤坏死因子-α在面对poly i:c时的产生情况会在小鼠面临耗尽式运动时被维持住
Masataka Uchida,Eri Oyanagi,Michael J Kremenik et al.
Masataka Uchida et al.
It remains unclear whether immune response to viral infection is inhibited by severe exercise. We determined whether exhaustive exercise inhibits interferon (IFN)-β and tumor necrosis factor (TNF)-α production after injection of synthetic...
Inhibition of ecto-ATPase activity by curcumin in hepatocellular carcinoma HepG2 cells [0.03%]
姜黄素通过抑制细胞外核苷酸酶的活性降低肝癌细胞胞外腺苷浓度的研究
Takuto Fujii,Takuma Minagawa,Takahiro Shimizu et al.
Takuto Fujii et al.
Effects of curcumin, a major constituent of turmeric, on ecto-nucleotidases have not been clarified. Here, we investigated whether curcumin affects ecto-nucleotidase activities in human hepatocellular carcinoma HepG2 cells. In the cells, hi...
Effects of alfacalcidol on circulating cytokines and growth factors in rat skeletal muscle [0.03%]
骨化二醇对大鼠骨骼肌循环细胞因子和生长因子的影响
Janwillem Testerink,Richard T Jaspers,Jörn Rittweger et al.
Janwillem Testerink et al.
Supra-physiological levels of vitamin D induce skeletal muscle atrophy, which may be particularly detrimental in already sarcopaenic elderly. Neither the cause nor whether the atrophy is fibre type specific are known. To obtain supraphysiol...
Intermittent arm ischemia induces vasodilatation of the contralateral upper limb [0.03%]
间断性上肢缺血可引起对侧上肢血管舒张
Kenki Enko,Kazufumi Nakamura,Kei Yunoki et al.
Kenki Enko et al.
Intermittent arm ischemia before percutaneous coronary intervention induces remote ischemic preconditioning (RIPC) and attenuates myocardial injury in patients with myocardial infarction. Several studies have shown that intermittent arm isc...
Sarcomere length-dependent Ca2+ activation in skinned rabbit psoas muscle fibers: coordinated regulation of thin filament cooperative activation and passive force [0.03%]
兔腰大肌去盖肌纤维的肌节长度依赖性钙离子激活：细丝协同活化和被动张力的协调调节
Norio Fukuda,Takahiro Inoue,Mitsunori Yamane et al.
Norio Fukuda et al.
In skeletal muscle, active force production varies as a function of sarcomere length (SL). It has been considered that this SL dependence results simply from a change in the overlap length between the thick and thin filaments. The purpose o...
Differential gene expression of muscle-specific ubiquitin ligase MAFbx/Atrogin-1 and MuRF1 in response to immobilization-induced atrophy of slow-twitch and fast-twitch muscles [0.03%]
慢缩肌和快缩肌在失用性萎缩过程中特异性表达肌肉型泛素连接酶MAFbx/Atrogin-1和MuRF1的mRNA变化规律研究
Takeshi Okamoto,Suguru Torii,Shuichi Machida
Takeshi Okamoto
We examined muscle-specific ubiquitin ligases MAFbx/Atrogin-1 and MuRF1 gene expression resulting from immobilization-induced skeletal muscle atrophy of slow-twitch soleus and fast-twitch plantaris muscles. Male C57BL/6 mice were subjected ...
Endothelin-induced changes in blood flow in STZ-diabetic and non-diabetic rats: relation to nitric oxide synthase and cyclooxygenase inhibition [0.03%]
内皮素引起的链脲佐菌素糖尿病和非糖尿病大鼠的血流变化与一氧化氮合酶和环氧化酶抑制的关系
Sven-Olof Granstam,Elisabet Granstam
Sven-Olof Granstam
In this study, using the microsphere method, the hemodynamic response to endothelin-1 (ET-1) in healthy and streptozotocin (STZ)-diabetic rats was evaluated as well as the influences of inhibition of nitric oxide (NO)-synthase using L-NAME ...