Computer-aided analysis of biochemical mechanisms that increase metabolite and proton stability in the heart during severe hypoxia and generate post-ischemic PCr overshoot [0.03%]
计算机辅助分析在严重低氧时增加心脏代谢物和质子稳定性以及产生缺血后PCr过剩的生化机制
Bernard Korzeniewski
Bernard Korzeniewski
During severe hypoxia in the heart, impaired supply of ATP by oxidative phosphorylation could lead to a great drop in ATP turnover and heart work. Anaerobic glycolysis enables unchanged ATP turnover to be maintained, but leads to huge chang...
Frequent alternate muscle activity of plantar flexor synergists and muscle endurance during low-level static contractions as a function of ankle position [0.03%]
足踝在不同位置时，在静态低强度收缩过程中足跖屈肌群的协同肌间频繁交替活动及其耐力之间的关系研究
Hiroyuki Tamaki,Hikari Kirimoto,Kengo Yotani et al.
Hiroyuki Tamaki et al.
We have investigated the appropriate joint angle for detecting frequent alternating activity in synergistic muscles and the relationship between muscle activation patterns and endurance during static low-level contractions. Eleven healthy m...
Sex differences in the recognition of emotional prosody in late childhood and adolescence [0.03%]
晚期末和青春期情感语调识别的性别差异
Takashi X Fujisawa,Kazuyuki Shinohara
Takashi X Fujisawa
We examined sex-related differences in the ability to recognize emotional prosody in late childhood (9-12 year olds) and adolescence (13-15 year olds) in relation to salivary testosterone levels. In order to examine both the accuracy and th...
Genki Minamisawa,Kenta Funayama,Norio Matsuki et al.
Genki Minamisawa et al.
Animals collect sensory information through self-generated movements. Muscle movements drive active feedback of sensory information and determine large parts of the sensory inputs the animal receives; however, little is known about how this...
Computational assessment of insulin secretion and insulin sensitivity from 2-h oral glucose tolerance tests for clinical use for type 2 diabetes [0.03%]
用于临床2型糖尿病的口服葡萄糖耐量试验的胰岛素分泌和胰岛素敏感性的计算评估
Masayoshi Seike,Takeo Saitou,Yasuhiro Kouchi et al.
Masayoshi Seike et al.
In type 2 diabetes mellitus, glucose homeostasis is tightly maintained through insulin secretion and insulin sensitivity. Therefore, finding an accurate method to assess insulin secretion and sensitivity using clinically available data woul...
Comparison of protein behavior between wild-type and G601S hERG in living cells by fluorescence correlation spectroscopy [0.03%]
荧光相关光谱检测野生型和带有G601S突变的人类快速延迟整流钾离子电流通道蛋白在活细胞中的行为差异比较
Eri H Hayakawa,Michiko Furutani,Rumiko Matsuoka et al.
Eri H Hayakawa et al.
The human ether-a-go-go-related gene (hERG) protein is a cardiac potassium channel. Mutations in hERG can result in reductions in membrane channel current, cardiac repolarization, prolongation of QT intervals, and lethal arrhythmia. In the ...
Involvement of energetic metabolism in the effects of ischemic postconditioning on the ischemic-reperfused heart of fed and fasted rats [0.03%]
缺血后处理对喂养和禁食大鼠心肌缺血再灌注损伤作用的差异与能量代谢的关系研究
M G Marina Prendes,R Hermann,M E Torresin et al.
M G Marina Prendes et al.
The effects of ischemic-postconditioning (IPOC) on functional recovery and cell viability of ischemic-reperfused hearts from fed and fasted rats were studied in relation to triacylglycerol and glycogen mobilization, ATP content, glucose-6-p...
Electrical stimulation of the mesencephalic ventral tegmental area evokes skeletal muscle vasodilatation in the cat and rat [0.03%]
伏隔核的电刺激可诱发猫和大鼠骨骼肌血管舒张反应
Kanji Matsukawa,Tomoko Nakamoto,Nan Liang
Kanji Matsukawa
To test the hypothesis that the mesencephalic ventral tegmental area (VTA) plays a role in autonomic control of the cardiovascular system, we examined the cardiovascular effects of electrical stimulation of the mesencephalic ventral areas i...
ATP-dependent potassium channels and mitochondrial permeability transition pores play roles in the cardioprotection of theaflavin in young rat [0.03%]
茶黄素对年轻大鼠心脏保护作用与腺苷三磷酸依赖性钾通道及线粒体渗透性转换孔道的关系研究
Huijie Ma,Xinli Huang,Qian Li et al.
Huijie Ma et al.
Previous studies have confirmed that tea polyphenols possess a broad spectrum of biological functions such as anti-oxidative, anti-bacterial, anti-tumor, anti-inflammatory, anti-viral and cardiovascular protection activities, as well as ant...
A single bout of exercise promotes sustained left ventricular function improvement after isoproterenol-induced injury in mice [0.03%]
单次运动促进异丙肾上腺素致伤小鼠左心室功能持续改善
Sarah K Jimenez,Davinder S Jassal,Elissavet Kardami et al.
Sarah K Jimenez et al.
We have investigated whether acute (swimming) exercise is sufficient to have sustained beneficial effects against cardiac functional decline observed after high-dose isoproterenol administration. Mice were subjected to one bout of swimming ...