Chronic periodic fluid redistribution effect on muscle calcium in healthy subjects during prolonged hypokinesia [0.03%]
长期制动对健康受试者慢性周期性体液重新分布效应的影响研究-以肌肉钙代谢为例
Yan G Zorbas,Victor A Deogenov,Pavel L Merkov et al.
Yan G Zorbas et al.
Studies have shown that chronic periodic fluid shifting upwards is not sensed as excessive fluid volume and excretion mechanisms are not activated. To determine if chronic periodic fluid and volume shifting upwards can affect muscle calcium...
Subepithelial trypsin induces enteric nerve-mediated anion secretion by activating proteinase-activated receptor 1 in the mouse cecum [0.03%]
小鼠盲肠粘膜下蛋白酶通过激活蛋白酶活化受体1诱导神经介导的阴离子分泌
Osamu Ikehara,Hisayoshi Hayashi,Toshiharu Waguri et al.
Osamu Ikehara et al.
Serine proteases are versatile signaling molecules and often exert this function by activating the proteinase-activated receptors (PAR(1)-PAR(4)). Our previous study on the mouse cecum has shown that the PAR(1)-activating peptide (AP) and P...
Evaluation of left ventricular mechanical work and energetics of normal hearts in SERCA2a transgenic rats [0.03%]
评估SERCA2a转基因大鼠正常心脏的左心室机械功和能学状况
Guo-Xing Zhang,Koji Obata,Daisuke Takeshita et al.
Guo-Xing Zhang et al.
Cardiac sarcoplasmic reticulum (SR) Ca(2+)-ATPase (SERCA2a) is responsible for most of the Ca(2+) removal during diastole and a larger Ca(2+) handling energy consumer in excitation-contraction (E-C) coupling. To understand the cardiac perfo...
Differential consequences of protein kinase C activation during early and late hepatic ischemic preconditioning [0.03%]
蛋白激酶C在肝缺血预适应早期和晚期激活的不同后果
Nari Yun,Sung-Hwa Kim,Sun-Mee Lee
Nari Yun
Activation of protein kinase C (PKC) has been implicated in the protection of ischemic preconditioning (IPC), but the exact role of PKC in early and late hepatic IPC is still unclear. The present study was conducted in order to investigate ...
Patterns of salivary cortisol levels can manifest work stress in emergency care providers [0.03%]
唾液皮质醇水平的规律可以反映出急诊科医护人员的工作压力大小
Yasushi Nakajima,Takayuki Takahashi,Vivek Shetty et al.
Yasushi Nakajima et al.
To develop objective assessments of work fatigue, we investigated the patterns of changes in salivary cortisol levels in emergency care providers working extended work shifts. Fourteen subjects, comprising seven physicians and seven physici...
Role of 15-lipoxygenase/15-hydroxyeicosatetraenoic acid in hypoxia-induced pulmonary hypertension [0.03%]
缺氧性肺高血压中15-LO/15-HpETE的作用机制研究
Daling Zhu,Yajuan Ran
Daling Zhu
Pulmonary arterial hypertension (PAH) is a rare disease with a complex aetiology characterized by elevated pulmonary artery resistance, which leads to right heart ventricular afterload and ultimately progressing to right ventricular failure...
T cells affect thymic involution during puberty by inducing regression of the adrenal reticularis [0.03%]
T细胞通过诱导肾上腺皮质网状层退化来影响青春期胸腺萎缩
Yoshihiro Kushida,Sayaka Kumagai,Ken Gotoh et al.
Yoshihiro Kushida et al.
The thymus involutes after puberty, although the mechanism by which this process occurs remains poorly understood. The profile of thymic involution, which is inversely correlated with an increase in peripheral T cells, may indicate that the...
Voltage-dependent biphasic effects of chloroquine on delayed rectifier K(+)-channel currents in murine thymocytes [0.03%]
氯喹对小鼠胸腺细胞延迟整流钾通道电流的双向依赖电压效应
I Kazama,Y Maruyama,Y Murata et al.
I Kazama et al.
Lymphocytes are of rich in delayed rectifier K(+)-channels (Kv1.3) in their plasma membranes, and the channels play crucial roles in the lymphocyte activation and proliferation. Since chloroquine, a widely used anti-malarial drug, exerts im...
The relationship between ghrelin and adiponectin levels in breast milk and infant serum and growth of infants during early postnatal life [0.03%]
产后早期母乳ghrelint和adiponectin与婴儿相应血清水平及生长的关系研究
Gokhan Cesur,Fehmi Ozguner,Nigar Yilmaz et al.
Gokhan Cesur et al.
Ghrelin and adiponectin have been found in breast milk and are considered to take part in the regulation of growth and energy metabolism of infants. Our aims were to determine ghrelin and adiponectin levels in breast milk and serum samples ...
Yasuhiro Nishida,Megumi Tandai-Hiruma,Takehito Kemuriyama et al.
Yasuhiro Nishida et al.
Mean arterial pressure fluctuates depending on physical or psychological activity, but should be stable at rest at around 100 mmHg throughout an entire life in human. The causes of hypertension and the blood pressure regulation mechanisms h...