Physiology of the volume-sensitive/regulatory anion channel VSOR/VRAC. Part 1: from its discovery and phenotype characterization to the molecular entity identification [0.03%]
容积敏感/调节性阴离子通道VSOR/VRAC的生理学(一):从其发现及表型特征到分子实体鉴定
Yasunobu Okada
Yasunobu Okada
The volume-sensitive outwardly rectifying or volume-regulated anion channel, VSOR/VRAC, which was discovered in 1988, is expressed in most vertebrate cell types and is essentially involved in cell volume regulation after swelling and in the...
Two synergistic types of muscles were detected during forearm rotation exercise by T2 cumulative frequency curves using 0.2 T magnetic resonance imaging [0.03%]
低场磁共振T2累积频率曲线在前臂旋转运动中检测两种协同工作的肌肉类型
Masayoshi Takamori,Sumikazu Akiyama,Yoshiteru Seo et al.
Masayoshi Takamori et al.
The purpose of this study was the detection and characterization of synergistic muscle activity. Using T2-map MRI, T2 values for 10 forearm muscles in 11 healthy adult volunteers were obtained in the resting state and after isotonic forearm...
Microglia mediate the increase in slow-wave sleep associated with high ambient temperature [0.03%]
小胶质细胞介导环境高温诱发的慢波睡眠增多现象
Sena Hatori,Futaba Matsui,Zhiwen Zhou et al.
Sena Hatori et al.
An increase in ambient temperature leads to an increase in sleep. However, the mechanisms behind this phenomenon remain unknown. This study aimed to investigate the role of microglia in the increase of sleep caused by high ambient temperatu...
Keisuke Ikegami
Keisuke Ikegami
Intraocular pressure (IOP) plays a crucial role in glaucoma development, involving the dynamics of aqueous humor (AH). AH flows in from the ciliary body and exits through the trabecular meshwork (TM). IOP follows a circadian rhythm synchron...
Alteration of serotonin release response in the central nucleus of the amygdala to noxious and non-noxious mechanical stimulation in a neuropathic pain model rat [0.03%]
坐骨神经损伤大鼠模型中央杏仁核血清素释放反应的改变
Ryota Tokunaga,Hideshi Shibata,Mieko Kurosawa
Ryota Tokunaga
Previously, we found that serotonin (5-HT) release in the central nucleus of the amygdala (CeA) of anesthetized rats decreases in response to innocuous stroking of the skin, irrespective of stimulus laterality, but increases in response to ...
Influence of age on nicotinic cholinergic regulation of blood flow in rat's olfactory bulb and neocortex [0.03%]
年龄对尼古丁胆碱能调节大鼠嗅球和新皮质血流量的影响
Sae Uchida,Fusako Kagitani
Sae Uchida
The olfactory bulb receives cholinergic basal forebrain inputs as does the neocortex. With a focus on nicotinic acetylcholine receptors (nAChRs), this review article provides an overview and discussion of the following findings: (1) the nAC...
Regulation of myocardial contraction as revealed by intracellular Ca2+ measurements using aequorin [0.03%]
用aequorin测定细胞内Ca2+浓度对心肌收缩的调节研究
Satoshi Kurihara,Norio Fukuda
Satoshi Kurihara
Of the ions involved in myocardial function, Ca2+ is the most important. Ca2+ is crucial to the process that allows myocardium to repeatedly contract and relax in a well-organized fashion; it is the process called excitation-contraction cou...
Identification of hypothermia-inducing neurons in the preoptic area and activation of them by isoflurane anesthesia and central injection of adenosine [0.03%]
视前区致低体温神经元的鉴定及异氟醚吸入和腺苷中枢注射激活该神经元的作用
Erika Uchino,Ikue Kusumoto-Yoshida,Hideki Kashiwadani et al.
Erika Uchino et al.
Hibernation and torpor are not passive responses caused by external temperature drops and fasting but are active brain functions that lower body temperature. A population of neurons in the preoptic area was recently identified as such activ...
Ghinwa M Barakat,Wiam Ramadan,Ghaith Assi et al.
Ghinwa M Barakat et al.
Many hormones act on the hypothalamus to control hunger and satiety through various pathways closely associated with several factors. When food is present in the gastro intestinal (GI) tract, enteroendocrine cells (EECs) emit satiety signal...
Neurochemical mechanism of muscular pain: Insight from the study on delayed onset muscle soreness [0.03%]
肌肉痛的神经化学机制:延迟性肌肉酸痛的研究启示
Kazue Mizumura,Toru Taguchi
Kazue Mizumura
We reviewed fundamental studies on muscular pain, encompassing the characteristics of primary afferent fibers and neurons, spinal and thalamic projections, several muscular pain models, and possible neurochemical mechanisms of muscle pain. ...