The intake of monosodium aspartate attenuates aggression induced by post-weaning social isolation in an ADHD rat model [0.03%]
天冬氨酸单钠盐的摄入能缓解产后断奶社会隔离诱导的注意力缺陷多动症大鼠模型攻击行为加剧的现象
Yu Nishimura,Dewi Mustika,Shinya Ueno et al.
Yu Nishimura et al.
We investigated whether monosodium aspartate (MSA), an umami compound structurally analogous to monosodium glutamate (MSG), influences aggressive behavior in a rat model of attention-deficit/hyperactivity disorder. Spontaneously hypertensiv...
The coiled-coil domain of myosin-11 as a potential biomarker to detect patients with atherosclerotic cardiovascular disease risk [0.03%]
肌球蛋白-11的卷曲螺旋结构域可作为动脉粥样硬化性心血管疾病风险患者的潜在生物标志物
Lisa Takahashi,Hirofumi Tomiyama,Hiroki Kobori et al.
Lisa Takahashi et al.
Atherosclerosis leads to severe clinical complications, and biomarkers for asymptomatic atherosclerosis are desired. Plasma levels of myosin-11 have been reported to increase in patients with symptomatic atherosclerosis. To investigate the ...
Interaction between respiration and central motor control in autonomic cardiac regulation [0.03%]
自主心脏调节中呼吸与中枢运动控制的相互作用
Pauline Doussineau,Antoine Mariani,Laurent Reale et al.
Pauline Doussineau et al.
Adaptations in cardiac autonomic regulation induced by physical training are central to the health benefits of exercise. We investigated the interaction between central motor command, breathing rate, and expiration timing during an isolated...
Task-related attentional processes are distinctly modulated by respiration and RR interval variability [0.03%]
与呼吸和心率变异性相关的任务相关注意过程的调节不同
Nozomu H Nakamura,Kohzoh Yoshino,Masaki Fukunaga
Nozomu H Nakamura
Changes in reaction times (RTs) during attentional processing may be associated with the state of breathing. Although breathing and cardiac activity interact, the functional importance of the cardiorespiratory system for modulating attentio...
Role of purinergic activation and TRPC3 channels in the Frank-Starling mechanism [0.03%]
嘌呤能激活和瞬时受体电位通道TRPC3在Frank-Starling机制中的作用
Yumiko Chiba,Keiko Kaihara,Gentaro Iribe
Yumiko Chiba
TRPC3 channels are involved in the physiological and pathological myocardial responses to mechanical loads. However, the involvement of TRPC3 in the response to acute stretch, that is, the Frank-Starling mechanism, has not been comprehensiv...
Activation of aortic baroreceptors depresses the somato-lumbar sympathetic reflex, reducing hindlimb muscle contractile force [0.03%]
主动脉球囊扩张激活颈动脉窦甲肾上腺素能神经元抑制交感传出至下肢肌肉神经元
Nobuhiro Watanabe,Kotaro Takeno,Naoko H Tomioka et al.
Nobuhiro Watanabe et al.
We investigated whether the same sympathetic nerves innervate arteries and neuromuscular junctions and aortic baroreceptor stimulation reduces muscle force in rats. Histological analysis with fluorescent labeling revealed nicotinic acetylch...
Toward the promotion of "One Health" - part I: How do humans work to live together with humans, other organisms, and xenobiotics on Earth? [0.03%]
迈向“同一个健康”（One Health）——第一部分：人类如何在地球上与人、其他生物及外源物质共同生存？
Yumiko Imai,Shunsuke Kimura,Satoshi Kitajima et al.
Yumiko Imai et al.
Thirty years from now, society will be transformed by dramatic advances in digital transformation, life infrastructure, and personalized medicine. People will communicate seamlessly in virtual spaces, and older adults will enjoy more fulfil...
METTL14-mediated m6A modification of DUSP6 mRNA participating in postoperative cognitive dysfunction due to sevoflurane anesthesia [0.03%]
METTL14介导的DUSP6 mRNA m6A修饰参与异氟醚麻醉术后认知障碍
Shengfeng Deng,Guo Mu,Jun Li et al.
Shengfeng Deng et al.
Background: To investigate the mechanisms underlying sevoflurane-induced POCD, C57BL/6 J mice and SH-SY5Y cells were treated with sevoflurane for model establishment. ...
Macrophage depletion lowers blood pressure and reduces renal fibrosis progression in existing hypertension mice model [0.03%]
巨噬细胞耗竭可降低高血压小鼠模型血压并减少肾纤维化进展
Joseph Kasyoki Peter,Ryusuke Umene,Chia-Hsien Wu et al.
Joseph Kasyoki Peter et al.
Uncontrolled hypertension is a global health issue with 40 % of hypertensive patients not achieving blood pressure control with current therapies. Previously, we demonstrated renal macrophage infiltration during hypertension development wit...
Estrogen-dependent effects of vagotomy and endogenous opioids on temporomandibular joint-responsive neurons in trigeminal subnucleus caudalis [0.03%]
卵圆孔切术后内源性阿片肽对三叉神经脊束核下亚核颞下颌关节反应神经元的雌激素依赖效应
Akimasa Tashiro,David A Bereiter,Yuna Kani et al.
Akimasa Tashiro et al.
Temporomandibular joint (TMJ) disorders are common orofacial pain conditions influenced by multiple factors. This study examined how vagotomy and endogenous opioids affect TMJ-responsive neurons in the trigeminal subnucleus caudalis/cervica...