Keisuke Ikegami
Keisuke Ikegami
Intraocular pressure (IOP) plays a crucial role in glaucoma development, involving the dynamics of aqueous humor (AH). AH flows in from the ciliary body and exits through the trabecular meshwork (TM). IOP follows a circadian rhythm synchron...
Mechanisms of the TGF-β1/Smad3-signaling pathway in gender differences in alcoholic liver fibrosis [0.03%]
TGF-β1/Smad3信号通路在酒精性肝纤维化性别差异中的机制研究
Xiaomin Hong,Sanqiang Li,Renli Luo et al.
Xiaomin Hong et al.
The TGF-β1/Smad3-signaling pathway and gender differences were investigated in alcoholic liver fibrosis. Mice were divided into female normal, female model, male normal, and male model groups. Liver injury and fibrosis were assessed using ...
Regulation of myocardial contraction as revealed by intracellular Ca2+ measurements using aequorin [0.03%]
使用水母蛋白测量细胞内钙离子以揭示心肌收缩的调节机制
Satoshi Kurihara,Norio Fukuda
Satoshi Kurihara
Of the ions involved in myocardial function, Ca2+ is the most important. Ca2+ is crucial to the process that allows myocardium to repeatedly contract and relax in a well-organized fashion; it is the process called excitation-contraction cou...
Ghinwa M Barakat,Wiam Ramadan,Ghaith Assi et al.
Ghinwa M Barakat et al.
Many hormones act on the hypothalamus to control hunger and satiety through various pathways closely associated with several factors. When food is present in the gastro intestinal (GI) tract, enteroendocrine cells (EECs) emit satiety signal...
Strength training improves heart function, collagen and strength in rats with heart failure [0.03%]
力量训练可改善心衰大鼠的心功能、胶原和强度
Leisiane G Dias,Carlos H O Reis,Leonardo Dos Santos et al.
Leisiane G Dias et al.
Background/objectives: Myocardial infarction (MI) frequently leads to cardiac remodeling and failure with impaired life quality, playing an important role in cardiovascular deaths. Although physical exercise is a well-rec...
Thermal gradient ring for analysis of temperature-dependent behaviors involving TRP channels in mice [0.03%]
用于分析小鼠中与TRP通道相关的温度依赖行为的热梯度环
Tomoyo Ujisawa,Jing Lei,Makiko Kashio et al.
Tomoyo Ujisawa et al.
There are a lot of temperature-sensitive proteins including transient receptor potential (TRP) channels. Some TRP channels are temperature receptors having specific activation temperatures in vitro that are within the physiological temperat...
The role of GPR81-cAMP-PKA pathway in endurance training-induced intramuscular triglyceride accumulation and mitochondrial content changes in rats [0.03%]
GPR81-cAMP-PKA通路在耐力训练诱导的大鼠肌内甘油三酯积聚和线粒体含量变化中的作用
Lin Li,Xiangdeng Lai,Yihan Ni et al.
Lin Li et al.
The athlete's paradox phenomenon involves the accumulation of intramuscular triglycerides (IMTG) in both insulin-resistant and insulin-sensitive endurance athletes. Nevertheless, a complete understanding of this phenomenon is yet to be achi...
Impact of folic acid supplementation on ischemia‒reperfusion-induced kidney injury in rats: folic acid prophylactic role revisited [0.03%]
叶酸补充对大鼠缺血再灌注诱导的肾脏损伤的影响：重新审视叶酸的预防作用
Aya E H Hamed,Sherif Khedr,Elsayed Ghonamy et al.
Aya E H Hamed et al.
Folic acid (FA), with its anti-inflammatory and antioxidant properties, may offer protection against ischemia-reperfusion (IR) injury. This study investigated whether FA safeguards rat kidneys from IR by targeting high mobility group box-1 ...
Evaluation of colour vision impairment during acute hypobaric hypoxia in aviation medicine: a randomized controlled trial [0.03%]
航空医学中急性高原缺氧对色觉影响的评估：一项随机对照试验
F Liebold,W Adler,S Jansen et al.
F Liebold et al.
The digitization of aircraft cockpits places high demands on the colour vision of pilots. The present study investigates colour vision changes upon acute exposure to hypobaric hypoxia. The digital Waggoner Computerized Color Vision Test and...
Randomized Controlled Trial
The journal of physiological sciences : JPS. 2024 Feb 4;74(1):6. DOI:10.1186/s12576-024-00898-4 2024
Circ_0114428 knockdown inhibits ROCK2 expression to assuage lipopolysaccharide-induced human pulmonary alveolar epithelial cell injury through miR-574-5p [0.03%]
Circ_0114428敲低通过miR-574-5p抑制ROCK2表达以缓解脂多糖诱导的人肺泡上皮细胞损伤
Jing Zhao,Qin Zhao,Qiuxia Duan
Jing Zhao
Background: Sepsis-induced acute lung injury (ALI) accounts for about 40% of ALI, accompanied by alveolar epithelial injury. The study aimed to reveal the role of circular RNA_0114428 (circ_0114428) in sepsis-induced ALI....