Effects of cytochalasin D on relaxation process of skinned taenia cecum and carotid artery from guinea pig [0.03%]
Calphostin C和Cytochalasin D对麻醉豚鼠盲肠条和平动脉去膜肌条松弛过程的影响研究
Satoko Mihashi,Masaru Watanabe
Satoko Mihashi
Actin linked regulatory mechanisms are known to contribute contraction/relaxation in smooth muscle. In order to clarify whether modulation of polymerization/depolymerization of actin filaments affects relaxation process, we examined the eff...
Acetate ameliorates ovarian mitochondrial dysfunction in letrozole-induced polycystic ovarian syndrome rat model by improving mitofusin-2 [0.03%]
乙酸通过改善线粒体融合蛋白2治疗来瑞昔芬诱导的多囊卵巢综合征小鼠模型中的卵巢线粒体功能障碍
Kehinde S Olaniyi,Stephanie E Areloegbe
Kehinde S Olaniyi
Androgen excess and metabolic abnormality largely contribute to the pathogenesis of polycystic ovarian syndrome (PCOS), which primarily precipitates ovarian dysfunction and infertility in reproductive-age women. Impaired mitochondrial funct...
Negative regulation of thyroid adenoma-associated protein (THADA) in the cardiac glycoside-induced anti-cancer effect [0.03%]
甲状腺腺瘤相关蛋白（THADA）在强心苷诱导的抗癌效应中的负向调节作用
Mizuki Katoh,Takuto Fujii,Yoshiaki Tabuchi et al.
Mizuki Katoh et al.
Cardiac glycosides, known as inhibitors of Na+,K+-ATPase, have anti-cancer effects such as suppression of cancer cell proliferation and induction of cancer cell death. Here, we examined the signaling pathway elicited by cardiac glycosides i...
An interactive simulator to deepen the understanding of Guyton's venous return curve [0.03%]
一个互动模拟器以深化对Guyton静脉回流曲线的理解
Noritaka Mamorita,Akihiro Takeuchi,Hirotoshi Kamata
Noritaka Mamorita
Mean circulatory filling pressure, venous return curve, and Guyton's graphical analysis are basic concepts in cardiovascular physiology. However, some medical students may not know how to view and interpret or understand them adequately. To...
Correction: Regulation of myocardial contraction as revealed by intracellular Ca2+ measurements using aequorin [0.03%]
关于心肌收缩调控的订正：用荧光蛋白aequorin测定细胞内Ca２＋的振荡现象
Satoshi Kurihara,Norio Fukuda
Satoshi Kurihara
Influence of sex on sympathetic vasomotor outflow responses to passive leg raising in young individuals [0.03%]
性别对年轻个体被动抬腿试验交感神经血管反应的影响
Keisho Katayama,Kana Shiozawa,Jordan B Lee et al.
Keisho Katayama et al.
The purpose of this study was to clarify sex differences in the inhibition of sympathetic vasomotor outflow which is caused by the loading of cardiopulmonary baroreceptors. Ten young males and ten age-matched females participated. The parti...
Influence of age on nicotinic cholinergic regulation of blood flow in rat's olfactory bulb and neocortex [0.03%]
年龄对大鼠嗅球和新皮质的胆碱能调节的的影响
Sae Uchida,Fusako Kagitani
Sae Uchida
The olfactory bulb receives cholinergic basal forebrain inputs as does the neocortex. With a focus on nicotinic acetylcholine receptors (nAChRs), this review article provides an overview and discussion of the following findings: (1) the nAC...
Action of GABAB receptor on local network oscillation in somatosensory cortex of oral part: focusing on NMDA receptor [0.03%]
GABAB受体对口腔部分躯体感觉皮层局部网络振荡的作用：着重于NMDA受体
Hiroyuki Kanayama,Takashi Tominaga,Yoko Tominaga et al.
Hiroyuki Kanayama et al.
The balance of activity between glutamatergic and GABAergic networks is particularly important for oscillatory neural activities in the brain. Here, we investigated the roles of GABAB receptors in network oscillation in the oral somatosenso...
Alteration of serotonin release response in the central nucleus of the amygdala to noxious and non-noxious mechanical stimulation in a neuropathic pain model rat [0.03%]
神经病理性疼痛大鼠模型中枢杏仁核对机械性和非机械性刺激5-羟色胺释放反应的改变
Ryota Tokunaga,Hideshi Shibata,Mieko Kurosawa
Ryota Tokunaga
Previously, we found that serotonin (5-HT) release in the central nucleus of the amygdala (CeA) of anesthetized rats decreases in response to innocuous stroking of the skin, irrespective of stimulus laterality, but increases in response to ...
Lactational exposure to perfluorooctane sulfonate remains a potential risk in brain function of middle-aged male mice [0.03%]
母乳暴露于全氟辛烷磺酸仍然是中年雄性小脑功能的潜在风险
Ayane Ninomiya,Izuki Amano,Hiraku Suzuki et al.
Ayane Ninomiya et al.
Perfluorooctane sulfonate (PFOS) exerts adverse effects on neuronal development in young population. Limited evidences have shown that early-life PFOS exposure holds a potential risk for developing age-related neurodegenerative diseases suc...