The involvement and significance of M2 macrophages in neuropathic pain following spinal cord injury: a systematic review [0.03%]
脊髓损伤后M2型小胶质细胞/巨噬细胞在神经病理性疼痛发生发展中的作用及意义：系统综述
Aidin Shahrezaei,Maryam Sohani,Mohammadhassan Sohouli et al.
Aidin Shahrezaei et al.
Neuropathic pain (NeP) is a type of persistent pain initiated by diseases or injuries of the nervous system. Although the underlying pathophysiological mechanisms of NeP are poorly understood, the immune system plays a key role in this cond...
Kunitoshi Uchida
Kunitoshi Uchida
Temperature detection is essential for the survival and perpetuation of any species. Thermoreceptors in the skin sense body temperature as well as the temperatures of ambient air and objects. Since Dr. David Julius and his colleagues discov...
Gravitational change-induced alteration of the vestibular function and gene expression in the vestibular ganglion of mice [0.03%]
重力变化诱发小鼠前庭功能和前庭神经节基因表达的改变
Murat Bazek,Motoya Sawa,Kazuhiro Horii et al.
Murat Bazek et al.
Gravity has profoundly influenced life on Earth, yet how organisms adapt to changes in gravity remains largely unknown. This study examines vestibular plasticity, specifically how the vestibular system responds to altered gravity. We subjec...
TRPV2: a universal regulator in cellular physiology with a yet poorly defined thermosensitivity [0.03%]
TRPV2：一种具有尚未明确的温度敏感性的细胞生理普遍调节因子
Tabea C Fricke,Andreas Leffler
Tabea C Fricke
Transient receptor potential (TRP) ion channels serve as sensors for variations in ambient temperature, modulating both thermoregulation and temperature responsive cellular processes. Among these, the vanilloid TRP subfamily (TRPV) comprise...
Age-related histone H3.3 accumulation associates with a repressive chromatin in mouse tibialis anterior muscle [0.03%]
与小鼠胫前肌染色抑制相关的年龄相关组蛋白H3.3积累
Ryo Masuzawa,Hemilce Karina Rosa Flete,Junya Shimizu et al.
Ryo Masuzawa et al.
The present study aimed to investigate age-related changes in histone variant H3.3 and its role in the aging process of mouse tibialis anterior muscle. H3.3 level significantly increased with age and correlated with H3K27me3 level. Acute ex...
Role of the central nervous system in cell non-autonomous signaling mechanisms of aging and longevity in mammals [0.03%]
中枢神经系统在哺乳动物衰老和长寿的细胞非自主信号机制中的作用
Takuya Urushihata,Akiko Satoh
Takuya Urushihata
Multiple organs orchestrate the maintenance of proper physiological function in organisms throughout their lifetimes. Recent studies have uncovered that aging and longevity are regulated by cell non-autonomous signaling mechanisms in severa...
The influence of exercise intensity on comorbid anxious behavior in psychiatric conditions [0.03%]
运动强度对精神疾病共病焦虑行为的影响
Dong-Joo Hwang,Tae-Kyung Kim
Dong-Joo Hwang
Many experts have extensively studied the potential of exercise as a treatment option for psychiatric conditions, including depression and autism spectrum disorder (ASD). Despite their core symptoms, these conditions exhibits comparable com...
Age-related alteration of the involvement of CD36 for salivary secretion from the parotid gland in mice [0.03%]
小鼠年龄相关的调节CD36参与腮腺分泌作用的变化
Keitaro Satoh,Yuta Ohno,Haruna Nagase et al.
Keitaro Satoh et al.
This in vivo mouse model study was conducted to investigate the temporal alteration of the function of CD36 in salivary secretion. CD36 was highly expressed in the parotid gland of BALB/c mice. No significant variations were shown in the CD...
Microglia mediate the increase in slow-wave sleep associated with high ambient temperature [0.03%]
小胶质细胞介导环境高温诱发的慢波睡眠增加现象
Sena Hatori,Futaba Matsui,Zhiwen Zhou et al.
Sena Hatori et al.
An increase in ambient temperature leads to an increase in sleep. However, the mechanisms behind this phenomenon remain unknown. This study aimed to investigate the role of microglia in the increase of sleep caused by high ambient temperatu...
The interactive effects of different exercises and hawthorn consumption on the pain threshold of TMT-induced Alzheimer male rats [0.03%]
不同运动和山楂摄入对TMT致病阿尔兹海默症雄性大鼠痛阈的交互作用研究
Ensiyeh Almasi,Ali Heidarianpour,Maryam Keshvari
Ensiyeh Almasi
Exercise increases the pain threshold in healthy people. However, the pain threshold modulation effect of exercise and hawthorn is unclear because of its potential benefits in people with persistent pain, including those with Alzheimer's di...