Febuxostat ameliorates muscle degeneration and movement disorder of the dystrophin mutant model in Caenorhabditis elegans [0.03%]
Febuxostat 治疗改善了秀丽隐杆线虫中 Duchenne 型肌营养不良突变模型的肌肉退化和运动障碍问题
Sawako Yoshina,Luna Izuhara,Rei Mashima et al.
Sawako Yoshina et al.
Duchenne muscular dystrophy (DMD) is an inherited disorder with mutations in the dystrophin gene characterized by progressive muscle degeneration and weakness. Therapy such as administration of glucocorticoids, exon skipping of mutant genes...
Mechanism for exercise-mediated prevention against muscle wasting on extensor digitorum longus muscle in Spontaneously Diabetic Torii fatty rats [0.03%]
运动介导的自发性糖尿病脂肪型Tori大鼠趾长伸肌抗肌萎缩的机制研究
Hitoshi Kotake,Yuji Ogura,Shohei Yamada et al.
Hitoshi Kotake et al.
We previously reported the significant increase in limb muscle strength and cross-sectional area of the type IIb muscle fibers in the extensor digitorum longus (EDL) muscle in a type 2 diabetic animal model, with Spontaneously Diabetic Tori...
Cumulative effects of exercise training and consumption of propolis on managing diabetic dyslipidemia in adult women: a single-blind, randomized, controlled trial with pre-post-intervention assessments [0.03%]
单盲随机对照试验：联合运动训练和蜂胶摄入对成年女性糖尿病脂质异常的干预效果研究
Fatemeh Moayedi,Farzaneh Taghian,Khosro Jalali Dehkordi et al.
Fatemeh Moayedi et al.
Dyslipidemia is an imbalance of various lipids, and propolis, as a natural resinous viscos mixture made by Apis mellifera L. could improve in this condition. In this single-blind, randomized trial, 60 women with type 2 diabetes and dyslipid...
Pallidal GABA B receptors: involvement in cortex beta dynamics and thalamic reticular nucleus activity [0.03%]
苍白球GABAB受体：与皮层β频段节律及丘脑网状核活动的关系
Nelson Villalobos,Victor Manuel Magdaleno-Madrigal
Nelson Villalobos
The external globus pallidus (GP) firing rate synchronizes the basal ganglia-thalamus-cortex network controlling GABAergic output to different nuclei. In this context, two findings are significant: the activity and GABAergic transmission of...
Experimental carotid baroreceptor stimulation reduces blood flow velocities in the anterior and middle cerebral arteries of healthy individuals [0.03%]
实验性的颈动脉窦刺激可降低健康受试者大脑前、中动脉的血流速度
Gustavo A Reyes Del Paso,Casandra I Montoro,J Richard Jennings et al.
Gustavo A Reyes Del Paso et al.
This study investigated effects of experimental baroreceptor stimulation on bilateral blood flow velocities in the anterior and middle cerebral arteries (ACA and MCA) using functional transcranial Doppler sonography. Carotid baroreceptors w...
Involvement of cannabinoid receptors in depression of the putative nociceptive response in spinal cord preparations isolated from neonatal rats [0.03%]
大鼠幼仔脊髓片中痛觉传递抑制与大麻素受体的关系研究
Kayo Tsuzawa,Hiroshi Onimaru,Katsunori Inagaki et al.
Kayo Tsuzawa et al.
A metabolite of acetaminophen, AM404, which is an anandamide transporter inhibitor, induces analgesia mainly via activation of transient receptor potential channel 1 in the spinal cord, although the role of cannabinoid receptors remains to ...
High-intensity interval training alleviates exhaustive exercise-induced HSP70-assisted selective autophagy in skeletal muscle [0.03%]
高强度间歇训练通过减轻骨骼肌中HSP70介导的选择性自噬来缓解力竭运动引起的肌肉损伤
Jiao Lu,Liu-Mei Zhang,Jing-Jing Liu et al.
Jiao Lu et al.
This study was designed to probe the effect of chaperone-assisted selective autophagy (CASA) on the maintenance of proteostasis during exhaustive exercise and uncover the alteration of CASA in muscle fibers with pre-high-intensity interval ...
Evaluation of newly developed wearable ear canal thermometer, mimicking the application to activities on sports and labor fields [0.03%]
一种新型耳道式可穿戴体温计的评价：模拟运动和劳作场景下的应用评估
Issei Kato,Hironori Watanabe,Kei Nagashima
Issei Kato
We evaluated the reliability of a newly developed wearable ear canal thermometer based on three different experiments, in which ear canal and rectal temperature (Tear and Trec, respectively) were simultaneously monitored. In Experiment 1, p...
Physical exercise for a healthy pregnancy: the role of placentokines and exerkines [0.03%]
运动促进健康妊娠：胎盘激素与运动因子的作用机制
Hamed Alizadeh Pahlavani,Ismail Laher,Katja Weiss et al.
Hamed Alizadeh Pahlavani et al.
Complications such as diabetes and preeclampsia can occur during pregnancy. Moderate-intensity exercise can prevent such complications by releasing placentokines and exerkines, such as apelin, adiponectin, leptin, irisin, and chemerin. Exer...
Masoumeh Kourosh-Arami,Alireza Komaki,Masoumeh Gholami et al.
Masoumeh Kourosh-Arami et al.
Plasticity is a common feature of synapses that is stated in different ways and occurs through several mechanisms. The regular action of the brain needs to be balanced in several neuronal and synaptic features, one of which is synaptic plas...