Cost-effectiveness of mammography-based breast cancer screening in Jordan: a healthcare system perspective [0.03%]
约旦基于乳房X线摄影的乳腺癌筛查的成本效益分析:从卫生系统的角度考虑
Shoroq M Altawalbeh,Maha Gharaibeh,Lelyan Alothman et al.
Shoroq M Altawalbeh et al.
Background: Breast cancer is the most common cancer among women in Jordan, with many cases detected at advanced stages, leading to higher costs and poorer outcomes. Despite mammography's proven benefits for early detectio...
Crossing the milestone: landmark-based conditional survival after first-line CDK4/6 inhibitor therapy in HR+/HER2-metastatic breast cancer [0.03%]
里程碑式的生存分析:HR+/HER2-转移性乳腺癌一线使用CDK4/6抑制剂后的标志物指导的预后生存期研究
Tuğba Önder,Öztürk Ateş
Tuğba Önder
Background: In hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) metastatic breast cancer (mBC), cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) have transformed long-term disease co...
Next-generation endocrine therapy in HR+/HER2 - breast cancer: oral SERDs, ER-targeting innovations, and ctDNA-driven ESR1 mutation-guided switching [0.03%]
下一代HR+/HER2-乳腺癌内分泌治疗:口服SERD、ER靶向创新及ctDNA驱动的ESR1突变指导下的转换治疗
Nan Yao,Guoshuai Xu,Ning Duan et al.
Nan Yao et al.
Background: Endocrine therapy (ET) is the backbone of HR+/HER2 - breast cancer management, yet acquired resistance commonly emerges despite aromatase inhibitors (AIs) and CDK4/6 inhibitors. A key actionable mechanism is t...
Indocyanine green fluorescence angiography algorithm for determining additional anastomosis in deep inferior epigastric perforator flap for breast reconstruction [0.03%]
用于乳腺重建的腹壁下穿支皮瓣附加吻合的吲哚青绿荧光血管造影算法
Rie Hayasaka,Kenta Tanakura,Yukiko Kuramoto et al.
Rie Hayasaka et al.
Background: Intraoperative indocyanine green (ICG) fluorescence angiography (ICG-FA) is commonly used to detect areas with poor perfusion. Fat necrosis caused by poor perfusion is often associated with the use of deep inf...
PTX3 induces the expression of PD-L1 and promotes breast cancer immune escape [0.03%]
PTX3诱导PD-L1的表达并促进乳腺癌免疫逃逸
Liyuan Jing,Jie Lun,Jianxin Xu et al.
Liyuan Jing et al.
Background: Pentraxin 3 (PTX3) is an inflammatory mediator involved in tumorigenesis; however, its role in tumor immune evasion remains elusive. Herein, we demonstrate that PTX3 promotes immune evasion in breast cancer by...
Therapeutic mammoplasty in selected East Asian patients: oncologic safety and cosmetic outcomes [0.03%]
选择性东亚患者治疗性乳房整形术:肿瘤安全性及美容效果
Ryohei Katsuragi,Hisamitsu Zaha,Norie Abe et al.
Ryohei Katsuragi et al.
Background: Therapeutic mammoplasty (TM) is a well-established oncoplastic breast-conserving technique, particularly for patients with large ptotic breasts. However, evidence on the oncologic safety and cosmetic outcomes...
Effect of exercise based prehabilitation on postoperative pain in breast cancer patients: a systematic review with meta-analysis [0.03%]
基于运动的术前康复对乳腺癌患者术后疼痛的影响:系统综述与元分析
Asier Del Arco,Celia García-Chico,Kayvan Khoramipour et al.
Asier Del Arco et al.
Background: Postoperative pain is a common complication following breast cancer surgery, adversely influencing recovery and quality of life. Exercise-based prehabilitation, initiated before surgery to enhance physical rea...
Comparison of ultrasound visibility and retrieval success of two ultrasound-visible clips in targeted axillary dissection after neoadjuvant chemotherapy [0.03%]
新辅助化疗后腋窝送检阳性患者两种可视夹在靶区腋窝清扫术中声像图显影及手术夹取效果的比较研究
Naomi Sakamoto,Hiroki Matsui,Eisuke Fukuma
Naomi Sakamoto
Background: Targeted axillary dissection (TAD) is a less invasive alternative to axillary lymph node dissection (ALND) for patients with clinically node-positive breast cancer who convert to node-negative status after neo...
BARD1 and breast cancer genetic predisposition: case-control study and HRD signature analysis [0.03%]
BRCA1同系物BARD1与乳腺癌遗传易感性:病例对照研究和HRD特征分析
Marie-Florence Reveneau,Antoine De Pauw,Julien Masliah-Planchon et al.
Marie-Florence Reveneau et al.
Introduction: BARD1 germline pathogenic variants (gPV) have been primarily associated with moderate breast cancer risk but their rarity limits accurate risk assessment and tailored follow-up guidelines. Our study evaluate...
Reevaluating sentinel lymph node biopsy in older adults with T1 HR+/HER2- breast cancer: a SEER competing risk and nomogram study [0.03%]
美国癌症联合会分期T1期激素受体阳性/HER2阴性乳腺癌老年女性再次评估哨兵淋巴结活检:基于SEER竞争风险和预测模型研究
Ziqiang Wang,Yangyang Xie,Weijun Zhang et al.
Ziqiang Wang et al.
Background: Sentinel lymph node biopsy (SLNB) is the standard procedure for axillary staging. However, its necessity in older patients (≥ 70 years) with HR+/HER2- T1 breast cancer remains debated in the context of contem...