Development of micro-sequestra and associated histological changes in tooth extraction sockets of zoledronate-treated mice [0.03%]
唑来膦酸处理的小鼠拔牙窝内微焦灶的形成及组织学变化
Gaku Koizumi,Taku Murata,Akira Takigawa et al.
Gaku Koizumi et al.
Objectives: Administration of bisphosphonates to mice do not always impair healing after tooth extraction. However, it is unclear whether there are any histological differences between the macroscopically healed extractio...
Hyperglycemia in obese type 2 diabetes mellitus rats affects pulp wound healing [0.03%]
高血糖对肥胖2型糖尿病大鼠牙髓创面修复的影响
Rosa Baldeon-Gutierrez,Naoto Ohkura,Nagako Yoshiba et al.
Rosa Baldeon-Gutierrez et al.
Objective: Hyperglycemia in individuals with type 2 diabetes mellitus is associated with delayed wound healing, although the underlying mechanism remains unclear. Macrophages play a crucial role in the initiation, mainten...
Analysis of the distribution of HEV by immunohistochemistry using a mouse oral squamous cell carcinoma model [0.03%]
免疫组化分析利用小鼠口腔鳞状细胞癌模型检测HEV分布
Zixiao Ren,Aya Matsuda,Nako Maishi et al.
Zixiao Ren et al.
Objective: The density of tumor-associated high endothelial venule (TA-HEV) correlates with a favorable prognosis in various tumors, including oral squamous cell carcinoma (OSCC). Despite the association of TA-HEVs with a...
Effects of anti-RANKL and anti-PD-1 antibodies on cancer-induced osteolysis in mice [0.03%]
抗RANKL和抗PD-1抗体对小鼠癌症诱导的骨溶解的影响
Po-Chin Chao,Akiko Karakawa,Masahiro Hosonuma et al.
Po-Chin Chao et al.
Objectives: Denosumab, an anti-bone resorptive agent composed of the anti-receptor activator of nuclear factor-κB ligand (RANKL) monoclonal antibody, and nivolumab, an immune checkpoint inhibitor composed of the anti-pro...
Intentionally perforating the pulp chamber floor promotes M2 macrophage polarization in the dental pulp following tooth replantation in mice [0.03%]
有意刺穿牙髓室底促进小鼠牙齿复位后牙髓中M2型巨噬细胞极化
Hiroto Sano,Kuniko Nakakura-Ohshima,Angela Quispe-Salcedo et al.
Hiroto Sano et al.
Objectives: Perforation of the pulp floor prior to tooth replantation promotes tertiary dentin formation and reduces bonelike tissue formation in the pulp cavity. However, the mechanisms remain largely unclear. This study...
The unique molecular signature of TMJ as compared to the knee, demonstrates its susceptibility to osteoarthritis [0.03%]
与膝关节相比，下颌关节特异性的分子标志表明其易患骨关节炎
Rajnikant Dilip Raut,Chumki Choudhury,Amit Kumar Chakraborty et al.
Rajnikant Dilip Raut et al.
Objectives: Osteoarthritis (OA) is a debilitating joint disease that affects millions of people worldwide, with prominent effects on the temporomandibular joints (TMJs) and knee. Despite its prevalence, TMJ-OA remains und...
Sex determination and age estimation method using the trabecular structure of the third cervical vertebral body by head and neck CT in Japanese adults [0.03%]
基于头部和颈部CT的第三颈椎椎体骨小梁结构的性别判定及年龄估计方法研究
Akihiro Ochiai,Atsushi Iwawaki,Yusei Otaka et al.
Akihiro Ochiai et al.
Objectives: This study aimed to develop sex determination and age estimation equations using the trabecular structure of the third cervical vertebra from head and neck computed tomography (CT) images by analyzing bone mic...
Complete genome sequence of a tetracycline-resistant Streptococcus mutans strain carrying the tet(M) gene [0.03%]
携tet(M)基因四环素耐药性变异体的变形链球菌完整基因组序列
Saki Nishihama,Yujin Suzuki,Tomoaki Shintani et al.
Saki Nishihama et al.
Introduction: Tetracyclines are widely used in dental treatment. Here, we report the genomic information of the tetracycline-resistant Streptococcus mutans strain, HSM45, for the first time. ...
Identification of a transposon variant of Porphyromonas gingivalis expressing long Mfa1 fimbriae due to mfa2 inactivation [0.03%]
识别出一种转座子变异体的齿垢密螺旋体因mfa2失活表达长Mfa1菌毛
Naoyoshi Miwa,Miyuna Fujimoto,Kotaro Sakae et al.
Naoyoshi Miwa et al.
Objectives: Fimbriae expressed by Porphyromonas gingivalis, a periodontal pathogen, play a pivotal role in biofilm formation. In the type strain ATCC 33277, Mfa1 fimbriae form short structures anchored to the cell surface...
Journal of Oral Biosciences Proteolytic N-terminal processing of Mfa proteins in the periodontal pathogen Porphyromonas gingivalis [0.03%]
牙龈卟啉单胞菌中Mfa蛋白的蛋白酶N末端加工过程
Makoto Hirohata,Yoshikazu Naiki,Akihiro Oishi et al.
Makoto Hirohata et al.
Objectives: The asaccharolytic bacterium Porphyromonas gingivalis regulates biofilm formation through Mfa1 fimbriae, composed of the major subunit Mfa1 and accessory proteins including the putative tip adhesin Mfa4. These...