Gb3 synthase accelerates bone wound healing by promoting the proliferation and migration of osteoblasts [0.03%]
Gb3合成酶通过促进成骨细胞的增殖和迁移来加速骨伤口愈合
Airi Sana,Mayu Nagao,Koichi Furukawa et al.
Airi Sana et al.
Objectives: Bone formation in murine femoral cancellous bone is attenuated in Gb3 synthase knockout (Gb3S KO) mice deficient in Gb4 (globoside), a globo-series glycosphingolipid. However, whether Gb3S promotes bone wound ...
ROS-scavenging and antibacterial properties of polydopamine-coated, drug-loaded bovine serum albumin nanoparticles [0.03%]
聚多巴胺涂层载药牛血清白蛋白纳米颗粒的ROS清除及抗菌性能研究
Libin Yang,Yaoyang Li,Guohua Yang et al.
Libin Yang et al.
Objectives: Periodontitis is an inflammatory disease driven by dysbiotic dental plaque and is the leading cause of tooth loss in adults. We aimed to develop a reactive oxygen species (ROS)-responsive drug delivery system ...
Protein fractions associated with Prevotella intermedia suppress the growth of HSC-3 oral squamous cell carcinoma cells [0.03%]
与Prevotella intermedia相关的蛋白质组分可抑制HSC-3口腔鳞状细胞癌细胞的生长
Miyuki Kashiwabara,Machiko Kasai,Shintaro Nakano et al.
Miyuki Kashiwabara et al.
Objectives: Oral microbiomes are associated with the progression of oral squamous cell carcinoma (OSCC). Prevotella intermedia is associated with tumor progression; however, the direct effects of P. intermedia on OSCC cel...
Multiclass diagnostic performance and error patterns of a multimodal large language model in oral histopathology: A WHO-aligned study [0.03%]
多模态大型语言模型在口腔组织病理学中的多类诊断性能和错误模式：一项与WHO一致的研究
Fatma E A Hassanein,Muhammad Talha Hassan,Mariya Javed et al.
Fatma E A Hassanein et al.
Objectives: To evaluate the diagnostic performance, feature-level agreement, and error patterns of a multimodal large language model (MLLM) across the oral dysplasia-malignancy continuum. ...
Masticatory performance and fecal propionate levels in healthy young adults: a cross-sectional study [0.03%]
健康年轻人咀嚼性能与粪便丙酸盐水平的相关性横断面研究
Masamichi Kato,Koji Morita,Fumiko Nishio et al.
Masamichi Kato et al.
Objectives: Masticatory function may influence the gut microbial metabolism via mechanical and neurohumoral mechanisms. However, the relationship between microbial metabolites and systemic indicators in healthy adults rem...
Pharmacological effects of PTH1R agonists on jaw bone fracture, periodontitis, orthodontic treatment and MRONJ: a view from dosing regimen settings [0.03%]
剂量方案设置下的PTH1R激动剂在牙骨骨折、牙周炎、牙齿矫正及MRONJ的药理作用浅析
Atsuko Nakanishi-Kimura,Naoki Tsuji,Erica L Scheller et al.
Atsuko Nakanishi-Kimura et al.
Background: Parathyroid hormone (PTH) and PTH-related peptide (PTHrP) are endogenous ligands of PTH type I receptor (PTH1R), which are essential for skeletal development and homeostasis. Since the intermittent application...
RNA sequencing identifies histone modification as a key mechanism of human periodontal ligament cell response to hydrostatic pressure [0.03%]
RNA测序鉴定组蛋白修饰是人牙周韧带细胞水静压响应的关键机制
Takashi Miyano,Masaru Kaku,Toshihiro Sera
Takashi Miyano
Objectives: The periodontal ligament (PDL) is a mechanosensitive connective tissue that provides tooth support and oral function. Although mechanical stress regulates PDL cell behavior, the transcriptional response of PDL...
Mechanisms of metabolic dysfunction-associated steatohepatitis progression induced by periodontitis and therapeutic strategies [0.03%]
牙周炎诱导代谢紊乱相关steatohepatitis进展的机制及治疗策略研究
Hisako Furusho
Hisako Furusho
Background: Multiple factors contribute to the progression of metabolic dysfunction-associated steatohepatitis (MASH), which can lead to severe conditions, such as liver cirrhosis and hepatocellular carcinoma. Therefore, ...
Metformin suppresses periapical bone resorption in a mouse model of apical periodontitis in vivo and inhibits RANKL-induced osteoclastogenesis in vitro [0.03%]
二甲双胍在牙槽骨炎小鼠模型中抑制牙槽骨吸收及体外抑制RANKL诱导的破骨细胞生成作用
Faisal Alghamdi,Chunmei Ren,Kento Tazawa et al.
Faisal Alghamdi et al.
Objectives: Metformin (MET), a widely used antidiabetic drug, has recently gained attention for its anti-bone-resorptive properties. This study evaluated these effects in apical periodontitis (AP) and explored its underly...
Zinc transporter ZIP13 in mesenchymal tissues: From intracellular metal distribution to systemic homeostasis [0.03%]
间叶组织中的锌转运蛋白ZIP13：从细胞内金属分布到全身稳态
Takafumi Hara,Emi Yoshigai,Yuta Nakayama et al.
Takafumi Hara et al.
Background: Zinc is an essential trace element that plays pivotal roles in development, immunity, inflammation, and aging. Precise regulation of intracellular zinc distribution is mediated by zinc transporters of the ZIP ...