Bias in HD-ISS staging introduced by the FreeSurfer cross-sectional stream: Insights from the Huntington's Disease Young Adult Study (HD-YAS) [0.03%]
亨廷顿病青年研究（HD-YAS）对FreeSufer横断面流程引入的HD-ISS分期偏差的新见解
Harry Knights,Annabelle Coleman,Mena Farag et al.
Harry Knights et al.
Huntington's Disease Integrated Staging System (HD-ISS) stages are likely inclusion criteria in future clinical trials. Stage 1 volumetric cut-offs were derived using the FreeSurfer longitudinal stream (LG). However, trials will require cro...
Efficacy and safety of cholinesterase inhibitors and memantine for cognitive symptoms in patients with Huntington's disease: A systematic review [0.03%]
胆碱酯酶抑制剂和美金刚治疗亨廷顿病认知症状有效性和安全性的系统综述
Catarina Correia Rodrigues,Vanessa Carvalho,Filipa Dourado Sotero et al.
Catarina Correia Rodrigues et al.
BackgroundHuntington's Disease (HD) is an autosomal dominant neurodegenerative disorder. Clinical features encompass a broad spectrum of movement disorders, psychiatric and cognitive symptoms, often progressing to dementia and imposing a su...
Neuroinflammation in Huntington's disease: Causes, consequences, and treatment strategies [0.03%]
亨廷顿舞蹈病的神经炎症：原因、后果及治疗策略
Alina Blusch,Maria Björkqvist
Alina Blusch
Huntington's disease (HD) is a progressive neurodegenerative disorder, and increasing evidence suggests that inflammation, both central and peripheral, plays a role in disease progression. Neurohistology and neuroimaging studies illustrate ...
Xinhui Li,Shihua Li,Xiao-Jiang Li et al.
Xinhui Li et al.
Huntington's disease (HD) is a fatal neurodegenerative disorder characterized by progressive motor, cognitive, and psychiatric symptoms. Research efforts to understand and treat the disease have historically focused on neuronal pathology, b...
Mahmoud A Pouladi,Asa Petersen
Mahmoud A Pouladi
Osama Al-Dalahmah,James E Goldman
Osama Al-Dalahmah
Huntington's disease (HD) is a neurodegenerative disorder caused by a repeat expansion in the HTT gene. The disease is well known for severe and progressive loss of neurons in the caudate and putamen, although other areas are also involved....
Dysregulation of huntingtin interacting protein networks in human juvenile Huntington's disease brain [0.03%]
人类青少年亨廷顿舞蹈病脑中亨廷顿蛋白相互作用蛋白网络的失调
Sonia Podvin,Brin Rosenthal,Charles Mosier et al.
Sonia Podvin et al.
BackgroundHuman Huntington's disease (HD) is a genetic neurodegenerative disorder caused by the mutant HTT gene containing CAG repeat expansions, resulting in motor dysfunction and behavioral deficits. CAG repeats of 40-53 occur in adult HD...
Reliability and validity of the Huntington's Disease Everyday Functioning (Hi-DEF): A patient-reported measure of cognitive capacity on daily functioning in Huntington's disease [0.03%]
亨廷顿舞蹈病日常功能量表（Hi-DEF）的可靠性和有效性：一项关于亨廷顿舞蹈病患者日常生活认知能力的自我报告测量方法
Jennifer Petrillo,Ruta Sawant,Rebecca Rogers et al.
Jennifer Petrillo et al.
BackgroundThe Huntington's Disease (HD) Everyday Functioning (Hi-DEF) is a novel patient-reported outcome (PRO) scale developed to assess the impact of cognitive impairment on daily functioning in early HD patients.ObjectiveTo examine the p...
Epidemiology and clinical features of Huntington's disease in MENASA region: A systematic review and meta-analysis [0.03%]
中东和北非地区亨廷顿病的流行病学和临床特征：系统回顾和荟萃分析
Mehri Salari,Kamran Rezaei,Fatemeh Hojjati Pour et al.
Mehri Salari et al.
BackgroundGiven the scarcity of comprehensive data on Huntington's disease in many Asian and African countries, it is more effective to focus on specific regions where there is a significant concentration of available data.ObjectiveThis stu...
Peter A LeWitt,Bisena Bulica
Peter A LeWitt