Long-Term use of Modified Diets in Huntington's Disease: A Descriptive Clinical Practice Analysis on Improving Dietary Enjoyment [0.03%]
亨廷顿病患者的长期改 diet观察：改善饮食享受的临床实践分析
Bronwyn Moorhouse,Caroline A Fisher
Bronwyn Moorhouse
Dysphagia is a very common occurrence in Huntington's disease (HD). As such, many people with HD require texture modified diets. This commentary discusses the implications for individuals living long-term on modified diets, including the lo...
Analysis of White Adipose Tissue Gene Expression Reveals CREB1 Pathway Altered in Huntington's Disease [0.03%]
白质基因表达分析揭示亨廷顿病中CREB1通路改变
Andrew Christopher McCourt,Jennifer Parker,Edina Silajdžić et al.
Andrew Christopher McCourt et al.
Background: In addition to classical neurological symptoms, Huntington's disease (HD) is complicated by peripheral pathology and both the mutant gene and the protein are found in cells and tissues throughout the body. Des...
Exploring the Validity of the Short Version of the Problem Behaviours Assessment (PBA-s) for Huntington's disease: A Rasch Analysis [0.03%]
霍顿舞蹈病问题行为评估简表(PBA-s)信度检验-拉什分析法探究
George McNally,Hugh Rickards,Mike Horton et al.
George McNally et al.
Background: The short version of the Problem Behaviours Assessment (PBA-s) is the recommended outcome measure for behavioural symptoms in Huntington's disease. Rasch analysis was used to further investigate the measuremen...
Longitudinal Diffusion Tensor Imaging Shows Progressive Changes in White Matter in Huntington's Disease [0.03%]
纵向弥散张量成像显示亨廷顿舞蹈病中白质进行性变化
Sarah Gregory,James H Cole,Ruth E Farmer et al.
Sarah Gregory et al.
Background: Huntington's disease is marked by progressive neuroanatomical changes, assumed to underlie the development of the disease's characteristic symptoms. Previous work has demonstrated longitudinal macrostructural ...
Multicenter Study
Journal of Huntington's disease. 2015;4(4):333-46. DOI:10.3233/JHD-150173 2015
Functional Brain Correlates of Neuropsychiatric Symptoms in Presymptomatic Huntington's Disease: The IMAGE-HD Study [0.03%]
影像学研究：渐进性亨廷顿舞蹈病患者前症状期的精神病症状的功能脑相关因素：IMAGE-HD 研究
Govinda R Poudel,Shannon Driscoll,Juan F Domínguez D et al.
Govinda R Poudel et al.
Background: Neuropsychiatric disturbances are common in Huntington's Disease (HD) and have been observed in gene-positive individuals several years prior to the onset of motor symptoms. The neural mechanism underpinning t...
Andreas-Antonios Roussakis,Paola Piccini
Andreas-Antonios Roussakis
To date, little is known about how neurodegeneration and neuroinflammation propagate in Huntington's disease (HD). Unfortunately, no treatment is available to cure or reverse the progressive decline of function caused by the disease, thus c...
Determinants of Onset of Huntington's Disease with Behavioral Symptoms: Insight from 92 Patients [0.03%]
92例亨廷顿舞蹈病患者的临床分析：行为症状起病亚群的特点及影响因素分析
Abhishek Lenka,Nitish L Kamble,V Sowmya et al.
Abhishek Lenka et al.
Background: Huntington's disease (HD) is a genetically mediated neurodegenerative disorder characterized by presence of involuntary movements, behavioral problems and cognitive dysfunctions. Though few patients with HD ma...
Brain Cholesterol Synthesis and Metabolism is Progressively Disturbed in the R6/1 Mouse Model of Huntington's Disease: A Targeted GC-MS/MS Sterol Analysis [0.03%]
亨廷顿舞蹈病小鼠模型R6/1中脑胆固醇合成和代谢的紊乱：气相色谱质谱法分析甾醇类化合物的研究
Fabian Kreilaus,Adena S Spiro,Anthony J Hannan et al.
Fabian Kreilaus et al.
Background: Cholesterol has essential functions in neurological processes that require tight regulation of synthesis and metabolism. Perturbed cholesterol homeostasis has been demonstrated in Huntington's disease, however...
Loss of the Sexually Dimorphic Neuro-Inflammatory Response in a Transgenic Mouse Model of Huntington's Disease [0.03%]
亨廷顿舞蹈病转基因小鼠性二态神经炎症反应缺失
Thibault Renoir,Terence Y Pang,Yoshiko Shikano et al.
Thibault Renoir et al.
Background: We previously reported sex differences in depression-like behaviours in a mouse model of Huntington's disease (HD). Objective: ...
Productivity and Impact of the Top 100 Cited Huntington's Disease Investigators [0.03%]
高被引亨廷顿病研究者们的生产力及影响
Aaron A Sorensen,M&#x;hamed El Aisati,David Weedon
Aaron A Sorensen
Huntington's disease (HD), research has grown dramatically over the last 25 years of research to the point where an analysis of productivity is warranted. We have compiled a list of the 100 most-cited researchers in HD together with H-Indic...