Neuropathological Comparison of Adult Onset and Juvenile Huntington's Disease with Cerebellar Atrophy: A Report of a Father and Son [0.03%]
成人型及青少年型伴小脑萎缩的亨廷顿舞蹈病的神经病理学对比：一例父子报告
Caitlin S Latimer,Margaret E Flanagan,Patrick J Cimino et al.
Caitlin S Latimer et al.
Background: Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by a trinucleotide (CAG) repeat expansion in huntingtin (HTT) on chromosome 4. Anticipation can cause longer repeat expansion...
The Impact of Family History on the Clinical Features of Huntington's Disease [0.03%]
家族史对亨廷顿舞蹈病临床特征的影响分析
Gabe Kringlen,Lisa Kinsley,Sharon Aufox et al.
Gabe Kringlen et al.
Background: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder. In most cases the disease is inherited from a parent, although a considerable number of affected persons have no reported family h...
Observational Study
Journal of Huntington's disease. 2017;6(4):327-335. DOI:10.3233/JHD-170256 2017
Blair R Leavitt,Leslie M Thompson
Blair R Leavitt
Filipe B Rodrigues,Edward J Wild
Filipe B Rodrigues
Clinical Trials Corner of Journal of Huntington's Disease will regularly review ongoing and recently completed clinical trials in Huntington's disease. In this inaugural issue, we list all currently registered and ongoing clinical trials, e...
Physical Therapy and Exercise Interventions in Huntington's Disease: A Mixed Methods Systematic Review [0.03%]
亨廷顿病的物理治疗和运动干预：混合方法系统评价
Nora E Fritz,Ashwini K Rao,Deb Kegelmeyer et al.
Nora E Fritz et al.
Background: A number of studies evaluating physical therapy and exercise interventions in Huntington's disease have been conducted over the past 15 years. However, an assessment of the quality and strength of the evidence...
Jocelynn R Pearl,Laura M Heath,Dani E Bergey et al.
Jocelynn R Pearl et al.
Background: Huntington's disease (HD) is a fatal progressive neurodegenerative disease characterized by chorea, cognitive impairment and psychiatric symptoms. Retinal examination of HD patients as well as in HD animal mod...
Huntington's Disease and Diabetes: Chronological Sequence of its Association [0.03%]
亨廷顿病与糖尿病：其关联的先后顺序分析
María Teresa Montojo,Miguel Aganzo,Nieves González
María Teresa Montojo
Although Huntington's disease (HD) is primarily considered a rare neurodegenerative disorder, it has been linked to glucose metabolism alterations and diabetes, as has been described in other neuro syndromes such as Friedreich's ataxia or A...
Pilot Validation of Ambulatory Activity Monitors for Sleep Measurement in Huntington's Disease Gene Carriers [0.03%]
亨廷顿舞蹈病基因携带者中门诊活动监测器的睡眠测量 pilot 验证研究
Svetlana Maskevich,Ria Jumabhoy,Pierre D M Dao et al.
Svetlana Maskevich et al.
Sleep disturbance occurs early in Huntington's disease (HD). Consumer- and research-grade activity monitors may enable routine assessment of sleep disturbances in HD. We compared Actiwatch Spectrum Pro, Jawbone UP2 and Fitbit One to the gol...
Families Affected by Huntington's Disease Report Difficulties in Communication, Emotional Involvement, and Problem Solving [0.03%]
亨廷顿舞蹈症患者家庭在沟通、情感参与和解决问题方面的困难报告
Celine M H Jona,Izelle Labuschagne,Emily-Clare Mercieca et al.
Celine M H Jona et al.
Background: Family functioning in Huntington's disease (HD) is known from previous studies to be adversely affected. However, which aspects of family functioning are disrupted is unknown, limiting the empirical basis arou...
Reliability and Validity of the HD-PRO-TriadTM, a Health-Related Quality of Life Measure Designed to Assess the Symptom Triad of Huntington's Disease [0.03%]
用于评估亨廷顿病症状三联征的与健康相关的生活质量测量方法HD-PRO-Triad™ 的可靠性和有效性
Nicholas R Boileau,Julie C Stout,Janes S Paulsen et al.
Nicholas R Boileau et al.
Background: Huntington's disease (HD), is a neurodegenerative disorder that is associated with cognitive, behavioral, and motor impairments that diminish health related quality of life (HRQOL). The HD-PRO-TRIADTM is a qua...
Multicenter Study
Journal of Huntington's disease. 2017;6(3):201-215. DOI:10.3233/JHD-170238 2017