Hao Li,Chih-Ying Lee,Henri-Jacques Delecluse
Hao Li
Epidemiological studies have provided strong evidence that Epstein-Barr virus (EBV) lytic replication is linked to cancer development. Evidence of abortive lytic replication in some tumors and infections with recombinant viruses incapable o...
Blood virome research in myalgic encephalomyelitis/chronic fatigue syndrome: challenges and opportunities [0.03%]
肌痛性脑脊髓炎/慢性疲劳综合征中的血液病毒组研究:挑战与机遇
Dominic Obraitis,Dawei Li
Dominic Obraitis
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease with a complex clinical presentation and an unknown etiology. Various viral infections have been proposed as potential triggers of ME/CFS onset, but no sp...
Host-pathogen interactions of emerging zoonotic viruses: bats, humans and filoviruses [0.03%]
新出现的人畜共患病毒的宿主-病原体相互作用:蝙蝠、人类和丝状病毒
Grace Hood,Miles Carroll
Grace Hood
This paper provides an overview of the phenomena of cross-species transmission of viruses (known as spillover), focusing on the highly pathogenic filovirus family and their natural reservoir: bats. It also describes the host-pathogen relati...
Advancing zoonotic respiratory virus research through the use of organoids [0.03%]
通过使用类器官来推进人畜共患呼吸道病毒的研究
Meaghan Flagg,Emmie de Wit
Meaghan Flagg
Zoonotic viruses with the ability to replicate in the human respiratory tract pose a threat to public health. Organoids, which are highly representative, multicellular models representing specific organs or tissues, can aid in our understan...
Rachael Tarlinton,Alex D Greenwood
Rachael Tarlinton
The koala retrovirus, KoRV, is one of the few models for understanding the health consequences of retroviral colonization of the germline. Such colonization events transition exogenous infectious retroviruses to Mendelian traits or endogeno...
Seth D Judson,David W Dowdy
Seth D Judson
The 2013-2016 Ebola virus disease epidemic and the coronavirus disease 2019 pandemic galvanized tremendous growth in models for emerging zoonotic and vector-borne viruses. Therefore, we have reviewed the main goals and methods of models to ...
Hafiz S Zafar,Haji Akbar,Huai Xu et al.
Hafiz S Zafar et al.
Oncogenic viruses play a pivotal role in oncology due to their unique role in unraveling the complexities of cancer development. Understanding the role viruses play in specific cancers is important to provide basic insights into the transfo...
Editorial overview: The lung, the gut, and the genital mucosae: microbial targets and therapeutic playgrounds [0.03%]
主编按语:肺、肠和生殖黏膜:微生物靶点与治疗 playgrounds
Jean-Michel Sallenave,Zhou Xing
Jean-Michel Sallenave
Hepatitis C virus and hepatocellular carcinoma: carcinogenesis in the era of direct-acting antivirals [0.03%]
丙型肝炎病毒与肝细胞癌:直接抗病毒药物时代的致癌作用
Felix Fiehn,Claudia Beisel,Marco Binder
Felix Fiehn
Chronic hepatitis C virus (HCV) infection is a major cause of hepatic fibrosis and cirrhosis, with a risk for the development of hepatocellular carcinoma (HCC). Although highly effective direct-acting antivirals (DAAs) are available, the in...
Luca D Bertzbach,Wing-Hang Ip,Konstantin von Stromberg et al.
Luca D Bertzbach et al.
Oncogenic viruses contribute to 15% of global human cancers. To achieve that, virus-encoded oncoproteins deregulate cellular transcription, antagonize common cellular pathways, and thus drive cell transformation. Notably, adenoviruses were ...