B V Venkataram Prasad,Sreejesh Shanker,Liya Hu et al.
B V Venkataram Prasad et al.
A critical event in the life cycle of a virus is its initial attachment to host cells. This involves recognition by the viruses of specific receptors on the cell surface, including glycans. Viruses typically exhibit strain-dependent variati...
Nardus Mollentze,Roman Biek,Daniel G Streicker
Nardus Mollentze
Despite its ability to infect all mammals, Rabies virus persists in numerous species-specific cycles that rarely sustain transmission in alternative species. The determinants of these species-associations and the adaptive significance of ge...
Virus interactions with endothelial cell receptors: implications for viral pathogenesis [0.03%]
病毒与内皮细胞受体的相互作用:对病毒发病机制的意义
Nadine A Dalrymple,Erich R Mackow
Nadine A Dalrymple
The endothelial lining of the vasculature performs a vital role in maintaining fluid barrier functions despite balancing nutrient and fluid content of tissues, repairing localized damage, coordinating responses of a plethora of factors, imm...
Darren J Obbard,Gytis Dudas
Darren J Obbard
Although viral infection and antiviral defence are ubiquitous, genetic data are currently unavailable from the vast majority of animal phyla-potentially biasing our overall perspective of the coevolutionary process. Rapid adaptive evolution...
The games plant viruses play [0.03%]
植物病毒的游戏
Santiago F Elena,Guillermo P Bernet,José L Carrasco
Santiago F Elena
Mixed virus infections in plants are common in nature. The outcome of such virus-virus interactions ranges from cooperation and coexistence (synergism) to mutual exclusion (antagonism). A priori, the outcome of mixed infections is hard to p...
Gillian M Air
Gillian M Air
It has been known for many years that influenza viruses bind by their hemagglutinin surface glycoprotein to sialic acid (N-acetylneuraminic acid) on the surface of the host cell, and that avian viruses most commonly bind to sialic acid link...
Lin-Ya Huang,Sujata Halder,Mavis Agbandje-McKenna
Lin-Ya Huang
Members of the Parvoviridae utilize glycan receptors for cellular attachment and subsequent interactions determine transduction efficiency or pathogenic outcome. This review focuses on the identity of the glycan receptors utilized, their ca...
Glycan-dependent viral infection in infants and the role of human milk oligosaccharides [0.03%]
婴儿病毒性感染的糖链依赖性及人乳低聚糖的作用机制
Sabrina Etzold,Lars Bode
Sabrina Etzold
Glycan interactions play a crucial role in the infection of rotavirus (RV), norovirus (NV) and human immunodeficiency virus (HIV) as they facilitate viral attachment to the host receptor cell. A number of cell surface glycan epitopes involv...
Tom C Hobman,Craig McCormick
Tom C Hobman
Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance [0.03%]
单纯疱疹病毒感染的当前及未来治疗方案:作用机制和药物抗性
Scott H James,Mark N Prichard
Scott H James
Forty years after the discovery of acyclovir (ACV), it remains the mainstay of therapy for herpes simplex virus (HSV) infections. Since then, other antiviral agents have also been added to the armamentarium for these infections but ACV rema...