Efficacy of beta-blocker agents on clinical outcomes in patients with thoracic aortic aneurysm: A systematic review and meta-analysis of randomized controlled trials [0.03%]
β受体阻滞剂对胸主动脉瘤患者临床结局影响的系统评价和 Meta分析
Lokman H Tanriverdi,Annie Barrett,Asanish Kalyanasundaram et al.
Lokman H Tanriverdi et al.
Objective: Studies investigating the efficacy of β-blocker agents for patients with thoracic aortic aneurysm (TAA) have produced heterogeneous and conflicting results. We assess the effects of β-blockers on clinical out...
IL-1β inhibition in stabilizing atherosclerotic plaques: The critical role of fibroblast-like cells [0.03%]
白细胞介素-1β抑制在稳定动脉粥样硬化斑块中的作用:成纤维细胞样细胞发挥关键作用
He Xu,Judith Sluimer
He Xu
Targeting interleukin-1 beta (IL-1β) to mitigate inflammation is known to stabilize atherosclerotic plaques, thereby lowering the risk of acute cardiovascular events. The precise mechanisms are not yet known. Fideler et al. examined the ef...
Sara M P Lambrichts,Robert J van Oostenbrugge,Sébastien Foulquier
Sara M P Lambrichts
Cerebral small vessel disease (cSVD) is a major cause of vascular cognitive impairment and dementia. The underlying disease mechanisms are centered around the dysfunction of the neurovascular unit and include an impairment of the blood-brai...
Clinical translation of mesenchymal stem cells in ischemic heart failure: Challenges and future perspectives [0.03%]
缺血性心力衰竭中间充质干细胞的临床转化:挑战和未来展望
Anqi Guan,Lisa Alibrandi,Elika Verma et al.
Anqi Guan et al.
Myocardial infarction (MI) with resulting congestive heart failure is one of the leading causes of death worldwide. Current therapies for treating MI, such as devices, traditional medicine, and surgeries, come with many limitations as patie...
TNAP expressing adventitial pericytes contribute to myogenesis during foetal development [0.03%]
胎盘发育过程中表达TNAP的外膜周细胞对肌源性分化的作用
I Fancello,S Willett,C Castiglioni et al.
I Fancello et al.
Objective: During growth and differentiation of skeletal muscle, cell types other than canonical myoblasts can be recruited to a myogenic fate. Among these, TNAP+ pericytes can differentiate into skeletal or smooth muscle...
PCSK6 ablation in blood circulating cells increases atherosclerotic burden, but improves plaque stability by activating Th17-smooth muscle cell modulatory axis [0.03%]
血液循环细胞中PCSK6的缺失增加了动脉粥样硬化的负担,但通过激活Th17-平滑肌细胞调节轴来改善斑块的稳定性
Bianca E Suur,Glykeria Karadimou,Colin J J M Willems et al.
Bianca E Suur et al.
Background: Proprotein convertase subtilisins/kexins (PCSKs) have been implicated in cancers and cardiovascular disease. We have shown that PCSK6 is a key protease regulating smooth muscle cell (SMC)-mediated vascular rem...
Macrophage and cardiomyocyte roles in cardioprotection: Exploiting the NLRP3 Inflammasome inhibitor INF150 [0.03%]
巨噬细胞和心肌细胞在心脏保护中的作用:利用NLRP3炎性小体抑制剂INF150
Magalì Giordano,Saveria Femminò,Federica Blua et al.
Magalì Giordano et al.
Background: Cardiovascular diseases remain the leading cause of disability and death in the Western world. Effective cardioprotection involves limiting ischemia/reperfusion injury (IRI), including cell death (pyroptosis) ...
Maia Lyall,Anna Kamdar,Robert Sykes et al.
Maia Lyall et al.
Vascular smooth muscle cell (VSMC) contractility mediates blood vessel tone. Abnormalities in VSMC function and in blood vessel tone can contribute to a variety of cardiovascular diseases. This review examines the role of VSMC contractile f...
Corrigendum to "Non-coding RNAs regulate angiogenic processes" [Vascular pharmacology 133-134 (2020) 106778] [0.03%]
《非编码RNA调节angiogenic过程》[血管药理学133-134(2020)106778]的勘误表
Soudeh Ghafouri-Fard,Hamed Shoorei,Mahdi Mohaqiq et al.
Soudeh Ghafouri-Fard et al.
Published Erratum
Vascular pharmacology. 2025 Mar 7:159:107486. DOI:10.1016/j.vph.2025.107486 2025
Interspecies differences in mitochondria: Implications for cardiac and vascular translational research [0.03%]
线粒体的种间差异:对心脏和血管转化研究的影响
Lisa Alibrandi,Vincenzo Lionetti
Lisa Alibrandi
Mitochondria are essential organelles that regulate cellular energy metabolism, redox balance, and signaling pathways related to proliferation, aging and survival. So far, significant interspecies differences exist in mitochondrial structur...