Exercise pulmonary hypertension in chronic thromboembolic pulmonary disease without resting pulmonary hypertension: A systematic review and meta-analysis [0.03%]
慢性血栓栓塞性肺疾病患者的运动性肺动脉高压：一项系统评价和荟萃分析
Filippo Biondi,Sandra Ghelardoni,Doralisa Morrone et al.
Filippo Biondi et al.
Exercise pulmonary hypertension (exPH) is currently defined as a mean pulmonary artery pressure to cardiac output slope (mPAP/CO slope) greater than 3 mmHg/L/min during the transition from rest to end-exercise, and a normal mPAP at rest. Ex...
Endothelial-to-mesenchymal transition primes vascular endothelial cells toward an osteochondrogenic fate [0.03%]
内皮细胞向间充质细胞转化使血管内皮细胞倾向于成软骨和成骨命运转换
Franceska Kishta,Ignacio Fernando Hall,Guanliang Li et al.
Franceska Kishta et al.
Endothelial-to-mesenchymal transition (EndMT), in which endothelial cells (ECs) lose their endothelial identity and acquire mesenchymal-like features, contributes to vascular dysfunction and remodeling in atherosclerosis. However, the fate ...
Hemodynamic markers: CFD-based prediction of cerebral aneurysm rupture risk [0.03%]
血流动力学标志物：基于计算流体力学的颅内动脉瘤破裂风险预测
Reza Bozorgpour
Reza Bozorgpour
Predicting which intracranial aneurysms will progress to rupture remains a major unmet need in neurosurgical practice. Conventional imaging provides limited insight into the hemodynamic forces acting on the aneurysm wall, yet these forces p...
Giovanna Manzi,Enrico Maggio,Tommaso Recchioni et al.
Giovanna Manzi et al.
Recent randomized clinical trials (RCTs) have demonstrated the efficacy of sotatercept in the treatment of pulmonary arterial hypertension (PAH), leading to its approval by both the U.S. Food and Drug Administration (FDA) and the European M...
RNA-seq and ChIP-seq reveal microplastics induce endothelial-mesenchymal transition via HK2-mediated histone lactylation in pulmonary hypertension [0.03%]
RNA测序和ChIP测序揭示微塑料通过HK2介导的组蛋白乳酸化诱导肺动脉高压中的内皮间质转化
Chuyan Long,Mouwen Lin,Wenjie Wang et al.
Chuyan Long et al.
Pulmonary hypertension (pH) is a life-threatening condition characterized by progressive pulmonary vascular remodeling, and endothelial-mesenchymal transition (EndMT) is recognized as a critical pathogenic process driving this remodeling. T...
Louise Frausto,Matthew L Scott,A Wayne Orr et al.
Louise Frausto et al.
Vascular smooth muscle cells (vSMCs) play a central role in atherosclerotic plaque development and stability through their remarkable phenotypic plasticity. In healthy vessels, contractile vSMCs maintain vascular tone and structural integri...
Nebivolol in the therapeutic landscape of heart failure: Mechanisms and clinical outcomes [0.03%]
奈倍洛尔在心力衰竭治疗格局中的作用机制与临床结局
Edoardo Roberto Ginghina,Giuseppe Biondi-Zoccai,Andrea Vitali et al.
Edoardo Roberto Ginghina et al.
Heart failure (HF) remains a major global health challenge, marked by clinical heterogeneity and high morbidity, especially among elderly and comorbid patients. While β-blockers are central to HF management, conventional agents often prese...
Amylin receptors as therapeutic targets in obesity: Emerging peptide-based strategies [0.03%]
肥胖症治疗靶点胰高血糖素受体(GLP-1R)和胰淀粉样多肽受体(amylin receptor):基于肽类药物的策略及其展望
Mokhtar Rejili,Md Sadique Hussain,Yumna Khan et al.
Mokhtar Rejili et al.
Obesity is a chronic, relapsing metabolic disorder driven by complex genetic and environmental factors, leading to an imbalance in energy regulation. Despite the presence of GLP-1 receptor agonists with induced mild weight loss, there are s...
ASPYRE-1 study: An Italian multicenter prospective study on pulmonary hypertension modality of death and validation of reveal risk score [0.03%]
ASPYRE-1研究：意大利多中心前瞻性肺动脉高压死亡方式的研究及验证 Reveal 风险评分的可靠性
Silvia Papa,Michele D&#x;Alto,Laura Scelsi et al.
Silvia Papa et al.
Background: Our understanding of pulmonary arterial hypertension (PAH) pathophysiology and treatment has significantly improved over time. Within this scenario we established the Italian Network on Pulmonary Arterial Hype...
Corrigendum to "Lack of AMP-activated protein kinase-α1 reduces nitric oxide synthesis in thoracic aorta perivascular adipose tissue" [Vascular Pharmacology 157 (2024)107437] [0.03%]
关于“缺乏AMP激活的蛋白激酶-α1减少胸主动脉周围脂肪组织一氧化氮合成”的勘误[Vascular Pharmacology 157 (2024)107437]
Abdmajid Hwej,Ali Al-Ferjani,Yazeed Alshuweishi et al.
Abdmajid Hwej et al.
Published Erratum
Vascular pharmacology. 2025 Nov 14:107560. DOI:10.1016/j.vph.2025.107560 2025