Hepatobiliary Clearance of a Long and Thick Carbon Nanotube following Pulmonary Exposure in Mice [0.03%]
小鼠经肺暴露长而厚的碳纳米管后的肝胆清除率
Mathilde Sundberg,Trine Berthing,Pernille Høgh Danielsen et al.
Mathilde Sundberg et al.
Long and thick carbon nanotubes (CNTs), such as Mitsui-7, can translocate from the lungs to secondary organs, including the liver, following pulmonary exposure. Although Mitsui-7 CNT is biopersistent, previous studies have suggested clearan...
Exposure to welding fumes and health effects: A systematic evaluation based on human biomonitoring analyses [0.03%]
焊接烟雾暴露与健康效应:基于人体生物监测分析的系统评估
Amir Hossein Khoshakhlagh,Safiye Ghobakhloo,Ulla Birgitte Vogel et al.
Amir Hossein Khoshakhlagh et al.
Background: Occupational exposure to heavy metals (HMs) through inhalation of welding emissions presents a serious health hazard to welders. This systematic review aimed to evaluate the concentrations of HMs in biological...
Excessive fluoride induces renal cell apoptosis and subsequent renal dysfunction [0.03%]
过量的氟导致肾细胞凋亡及后续的肾功能障碍
Yi Zhang,Zhao Xu,Pengpeng Xie et al.
Yi Zhang et al.
This study investigated the mechanisms of renal injury and dysfunction induced by chronic excessive fluoride exposure. Sixty female Sprague-Dawley rats were administered sodium fluoride (NaF) at 0, 50, 100, or 150 mg/L in drinking water for...
Histone H3K4 monomethyltransferase SETD7 promoted osteogenic differentiation of bone marrow mesenchymal stem cells exposed to Hydroquinone via autophagy [0.03%]
组蛋白H3K4单甲基转移酶SETD7通过自噬促进对苯二酚诱导的骨髓间充质干细胞成骨分化
Yilin Shen,Yibo Niu,Tao Xu et al.
Yilin Shen et al.
Hydroquinone (HQ), a major metabolite of benzene, is a recognized risk factor for acute myeloid leukemia (AML). However, the mechanisms underlying HQ-associated leukaemogenesis remain incompletely understood. Increasing evidence suggests th...
Identification of xenobiotics interfering with 5α-reductase (SRD5A2) activity [0.03%]
异源分子干扰5α-还原酶(SRD5A2)活性的识别
Jacek Kędzierski,Rianne E van Diest,Julien A Allard et al.
Jacek Kędzierski et al.
5α-Dihydroxytestosterone (DHT) is essential for male sexual development, and its synthesis from testosterone is mediated by the steroid 5α-reductase (SRD5A) isoenzymes, SRD5A1 and SRD5A2. SRD5A2 is the predominant isoform expressed in rep...
Dissolution of man-made vitreous fibres (MMVF) using the USP-4: Part I. Fluid choice for closed-loop configuration tests [0.03%]
人工玻璃纤维(AMVF)的溶解:第一部分。封闭式配置测试中的流体选择
Denis V Okhrimenko,Léa Hiéronimus,John W Hoffman et al.
Denis V Okhrimenko et al.
In this research, we extended our examination of the US pharmacopeia apparatus 4 (USP-4) application for the development of an in vitro acellular dissolution protocol for man-made vitreous fibres (MMVF1). The aim of this study was to achiev...
Recovery from Chronic PFAS Exposure Can Reverse Chemotherapy Resistance and Mitochondrial Alterations in Ovarian Cancer Cells [0.03%]
慢性PFAS暴露的恢复可以逆转卵巢癌细胞的化疗耐药性和线粒体改变
Brittany P Rickard,Lauren A Sapienza-Lundie,Vesna A Chappell et al.
Brittany P Rickard et al.
Perfluoroalkyl substances (PFAS) are environmental contaminants of global concern that have been associated with a variety of adverse health outcomes, including diminished chemotherapy response. Previous studies in chemosensitive ovarian ca...
Assessment of non-dietary human health risk based on concentration of multiresidue pesticides in soil of irrigated farmland around Lake Ziway, Ethiopia [0.03%]
基于赞维亚湖周边灌溉农田土壤中多种残留农药浓度的多残留农药非饮食暴露人体健康风险评估
Asrat Fekadu Demsie
Asrat Fekadu Demsie
Soil samples collected from irrigated farmlands around Lake Ziway were thoroughly analyzed for 35 different pesticides, yielding significant insights into contamination profiles and the non-dietary health risks associated with these substan...
Corrigendum to "Busulfan plus cyclophosphamide induced spermatogenic dysfunction and recovery: A dynamic change perspective" [Toxicol. Lett. 417(2026) 111833] [0.03%]
“丁酸钠对小鼠食管鳞癌的致癌作用及机制研究”一文勘误通知
Tianyu Li,Zhichen Tang,Yaping Song et al.
Tianyu Li et al.
Published Erratum
Toxicology letters. 2026 Feb 10:111856. DOI:10.1016/j.toxlet.2026.111856 2026
Toxicity and endocrine disrupting activity of monoanthraquinone dyes: Alizarin Blue Black B, Acid Blue 129 and Remazol Brilliant Blue R [0.03%]
单蒽醌染料的毒性及内分泌干扰活性:阿爾拉扎因藍黑色B、酸性蓝129和レ馬佐勒鲜艳蓝R
Kamila Rybczyńska-Tkaczyk,Bartosz Skóra,Konrad A Szychowski
Kamila Rybczyńska-Tkaczyk
The aim of this study was to determine the ecotoxicological and cytotoxic effects of monoanthraquinone dyes, i.e., Alizarin Blue Black B (ABBB), Acid Blue 129 (AB129), and Remazol Brilliant Blue R (RBBR), using Microbial Assay for Risk Asse...