Gorka Orive,Nayere Taebnia,Itsasne Erezuma et al.
Gorka Orive et al.
Imagine a world where machines can program cells to deliver therapeutics in a remote-controlled, time-specific, and targeted manner. Or, what if physicians could collect data continuously to establish intimate links between therapy and dise...
Peng Xu,Monireh Marsafari,Jian Zha et al.
Peng Xu et al.
Flavonoids are plant-derived natural products with human health-promoting benefits. The modularity and complexity of the flavonoid biosynthetic pathway allow us to leverage the metabolic characteristics of distinct microbial hosts and insta...
Guan Wang,Cees Haringa,Henk Noorman et al.
Guan Wang et al.
Bioprocess scale-up is a critical step in process development. However, loss of production performance upon scaling-up, including reduced titer, yield, or productivity, has often been observed, hindering the commercialization of biotech inn...
Non-Hydrolyzable Plastics - An Interdisciplinary Look at Plastic Bio-Oxidation [0.03%]
非水解塑料——关于塑料生物氧化的跨学科研讨会
Hedda Inderthal,Siew Leng Tai,Susan T L Harrison
Hedda Inderthal
Enzymatic plastic conversion has emerged recently as a potential adjunct and alternative to conventional plastic waste management technology. Publicity over progress in the enzymatic degradation of polyesters largely neglects that the major...
Saba Safdar,Jeroen Lammertyn,Dragana Spasic
Saba Safdar
Nucleic acid enzymes (NAzymes) are nucleic acid molecules with catalytic activity. A subset, the RNA-cleaving NAzyme, is characterized by its substrate of choice: an RNA unit. These enzymes have been used for diverse applications, including...
Katherine E Horak
Katherine E Horak
Sequence-directed inhibition of protein synthesis by RNAi has potential as a means to control pest wildlife. Species specific by design, RNAi reduces impacts on nontarget species and the environment. Additional research advancing the field ...
Morena Fiordalisi,Ana João Silva,Mário Barbosa et al.
Morena Fiordalisi et al.
In the last decade, intervertebral disc (IVD) decellularization has gained significant attention for tissue regenerative purposes as a successful therapeutic alternative for low back pain (LBP). We discuss the recent advances in IVD decellu...
Rethinking Cancer Immunotherapy by Embracing and Engineering Complexity [0.03%]
通过接纳和工程化复杂性来重新思考癌症免疫治疗
Matthew H W Chin,Eileen Gentleman,Marc-Olivier Coppens et al.
Matthew H W Chin et al.
The meteoric rise of cancer immunotherapy in the past decade has led to promising treatments for a number of hard-to-treat malignancies. In particular, adoptive T cell therapy has recently reached a major milestone with two products approve...
Multitechnology Biofabrication: A New Approach for the Manufacturing of Functional Tissue Structures? [0.03%]
多功能生物制造：用于制造功能性组织结构的新方法？
Miguel Castilho,Mylène de Ruijter,Stephen Beirne et al.
Miguel Castilho et al.
Most available 3D biofabrication technologies rely on single-component deposition methods, such as inkjet, extrusion, or light-assisted printing. It is unlikely that any of these technologies used individually would be able to replicate the...
Plant Microbiome Engineering: Expected Benefits for Improved Crop Growth and Resilience [0.03%]
植物微生物组工程：提高作物生长和抗逆性的预期效益
Inessa Arif,Maria Batool,Peer M Schenk
Inessa Arif
Plant-associated microbiomes can boost plant growth or control pathogens. Altering the microbiome by inoculation with a consortium of plant growth-promoting rhizobacteria (PGPR) can enhance plant development and mitigate against pathogens a...