Biotechnology for Tomorrow's World: Scenarios to Guide Directions for Future Innovation [0.03%]
面向未来的生物技术创新路线图： tomorrow’s biotechnological innovation scenarios
Marc Cornelissen,Aleksandra Małyska,Amrit Kaur Nanda et al.
Marc Cornelissen et al.
Depending on how the future will unfold, today's progress in biotechnology research has greater or lesser potential to be the basis of subsequent innovation. Tracking progress against indicators for different future scenarios will help to f...
International Reporting Mechanism for Unethical Germline Gene Editing Experiments Is Needed [0.03%]
需要国际机制来通报不合伦理的体细胞基因编辑实验
G Owen Schaefer,Markus K Labude,Yujia Zhu et al.
G Owen Schaefer et al.
Recent reporting found that a number of scientists internationally knew about the experiment resulting in the birth of the first gene-edited babies well before the news broke. Because scientists have a responsibility to reveal such activiti...
Jancy Johnson,Yu-Wen Wu,Chantelle Blyth et al.
Jancy Johnson et al.
There is much interest in the use of extracellular vesicles (EVs) as a subcellular therapy for regenerative medicine and drug delivery. Blood-borne platelets represent a source of therapeutic EVs that is so far largely unexplored. Advantage...
Sidney P Walker,Venkata V B Yallapragada,Mark Tangney
Sidney P Walker
Proteins mediate many essential processes of life to a degree of functional precision unmatched by any synthetic device. While engineered proteins are currently used in biotech, food, biomedicine, and material technology-based industries, t...
Sachin Dubey,Roberto Giovannini
Sachin Dubey
Most biopharmaceutical formulations use polysorbates: surfactants that are highly efficient but difficult to manage in terms of compositional variability, quality, and stability. Alternatives, such as poloxamers, albumin, and cyclodextrin, ...
H Ceren Ates,Jason A Roberts,Jeffrey Lipman et al.
H Ceren Ates et al.
Recent technological advances have stimulated efforts to bring personalized medicine into practice. Yet, traditional application fields like therapeutic drug monitoring (TDM) have remained rather under-appreciated. Owing to clear dose-respo...
Dominic R Whittall,Katherine V Baker,Rainer Breitling et al.
Dominic R Whittall et al.
Spider silk is renowned for its impressive mechanical properties. It is one of the strongest known biomaterials, possessing mechanical properties that outmatch both steel and Kevlar. However, the farming of spiders for their silk is unfeasi...
Understanding and Assisting Reproduction in Wildlife Species Using Microfluidics [0.03%]
利用微流控技术理解和协助野生动物物种的繁殖
Séverine Le Gac,Marcia Ferraz,Bastien Venzac et al.
Séverine Le Gac et al.
Conservation breeding and assisted reproductive technologies (ARTs) are invaluable tools to save wild animal species that are on the brink of extinction. Microfluidic devices recently developed for human or domestic animal reproductive medi...
SWATH-MS-Based Proteomics: Strategies and Applications in Plants [0.03%]
基于SWATH-MS的蛋白质组学：在植物中的策略与应用
Mo-Xian Chen,Youjun Zhang,Alisdair R Fernie et al.
Mo-Xian Chen et al.
Most applied proteomic approaches require labeling steps. Recent technological advances provide an alternative label-free proteomics approach: SWATH-MS. This powerful tool is now widely used in animal studies but has drawn far less attentio...
From Acetate to Bio-Based Products: Underexploited Potential for Industrial Biotechnology [0.03%]
从醋酸到生物基产品：工业生物技术中未充分利用的潜力
Dirk Kiefer,Manuel Merkel,Lars Lilge et al.
Dirk Kiefer et al.
Currently, most biotechnological products are based on microbial conversion of carbohydrate substrates that are predominantly generated from sugar- or starch-containing plants. However, direct competitive uses of these feedstocks in the foo...