Peter W E Kearns,Gijs A Kleter,Hans E N Bergmans et al.
Peter W E Kearns et al.
The OECD Council Recommendation on Recombinant DNA Safety Considerations is a legal instrument which has been in force since 1986. It outlines the safety assessment practices that countries should have in place for agricultural and environm...
Michel H M Eppink,Sónia P M Ventura,João A P Coutinho et al.
Michel H M Eppink et al.
Ionic liquids (ILs) are salts with low melting points that can be used as solvents for mild extraction and selective fractionation of biomolecules (e.g., proteins, carbohydrates, lipids, and pigments), enabling the valorisation of microalga...
Andreas Schoenit,Elisabetta Ada Cavalcanti-Adam,Kerstin Göpfrich
Andreas Schoenit
Due to its versatility and programmability, DNA nanotechnology has greatly expanded the experimental toolbox for biomedical research. Recent advances allow reliable and efficient functionalization of cellular plasma membranes with a variety...
Rolling Circle Replication for Biosensing, Bioimaging, and Biomedicine [0.03%]
滚圈复制在生物传感、生物成像和生物医学中的应用
Shuzhen Yue,Yuwei Li,Zhenjie Qiao et al.
Shuzhen Yue et al.
Rolling circle replication (RCR), including rolling circle amplification (RCA) and rolling circle transcription (RCT), is an isothermal enzymatic reaction. Because of its high amplification efficiency, RCR is a powerful biosensing tool for ...
Synthetic Biology towards Engineering Microbial Lignin Biotransformation [0.03%]
合成生物学助力工程微生物催化木质素转化
Allison L Yaguchi,Stephen J Lee,Mark A Blenner
Allison L Yaguchi
Lignin is the second most abundant biopolymer on earth and is a major source of aromatic compounds; however, it is vastly underutilized owing to its heterogeneous and recalcitrant nature. Microorganisms have evolved efficient mechanisms tha...
Antonio Gaetano Cardillo,Maria Monica Castellanos,Benoit Desailly et al.
Antonio Gaetano Cardillo et al.
Chemical, manufacturing, and control development timelines occupy a significant part of vaccine end-to-end development. In the on-going race for accelerating timelines, in silico process development constitutes a viable strategy that can be...
Baotong Zhu,Dong Wang,Na Wei
Baotong Zhu
The drastically increasing amount of plastic waste is causing an environmental crisis that requires innovative technologies for recycling post-consumer plastics to achieve waste valorization while meeting environmental quality goals. Biocat...
Philipp Knyphausen,Laurens Lindenburg,Florian Hollfelder
Philipp Knyphausen
Synthetic DNA is the linchpin of the rapidly accelerating biotechnological era and is perhaps the most promising candidate for long-term digital data storage. Despite huge advances, manufacturing error-free DNA at low cost and high throughp...
Directed Evolution of Propionyl-CoA Carboxylase for Succinate Biosynthesis [0.03%]
丙二酸辅酶a羧化酶的定向进化以生物合成琥珀酸
Yuwan Liu,Huifeng Jiang
Yuwan Liu
Due to low carboxylase activity, CO2 biotransformation is challenging to achieve using natural CO2 fixation pathways. Liu et al. have improved the activity of propionyl-CoA carboxylase (PCC) 94-fold, enabling the efficient synthesis of succ...
Nico J Claassens
Nico J Claassens
Hong et al. heterologously expressed the metabolic core of the reductive glycine pathway (rGlyP) as a sink for the anaerobic conversion of glycerol. This recent study concludes several reports in 2020 on the ATP-efficient, one-carbon-assimi...