Multiproduct biorefinery from marine thraustochytrids towards a circular bioeconomy [0.03%]
来自海洋Thraustochytrids的多产品生物精炼厂迈向循环经济
Adarsha Gupta,Colin J Barrow,Munish Puri
Adarsha Gupta
Microalgal biotechnology research continues to expand due to largely unexplored marine environments and growing consumer interest in healthy products. Thraustochytrids, which are marine oleaginous protists, are known for their production of...
Customizing lipids from oleaginous microbes: leveraging exogenous and endogenous approaches [0.03%]
来自产油微生物的脂质定制：利用外源性和内源性方法
Bijaya K Uprety,Erin N Morrison,R J Neil Emery et al.
Bijaya K Uprety et al.
To meet the growing demands of the oleochemical industry, tailored lipid sources are expanding to oleaginous microbes. To control the fatty acid composition of microbial lipids, ground-breaking exogenous and endogenous approaches are being ...
The spatial position effect: synthetic biology enters the era of 3D genomics [0.03%]
空间位置效应：合成生物学进入三维基因组时代
Zhou Li,He Yang,Yifei Wang et al.
Zhou Li et al.
Microbial cell factories are critical to achieving green biomanufacturing. A position effect occurs when a synthetic gene circuit is expressed from different positions in the chassis strain genome. Here, we propose the concept of the 'spati...
Jian-Ming Liu,Christian Solem,Ting Lu et al.
Jian-Ming Liu et al.
Lactic acid bacteria (LAB) are important members in synthetic microbial consortia due to their 'generally recognized as safe' status and diverse metabolic activities. Defined communities with LAB show great potential in elucidating metaboli...
3D-bioprinted cancer-on-a-chip: level-up organotypic in vitro models [0.03%]
3D生物打印的芯片上的癌症模型：器官型体外模型的升级版本
Maria V Monteiro,Yu Shrike Zhang,Vítor M Gaspar et al.
Maria V Monteiro et al.
Combinatorial conjugation of organ-on-a-chip platforms with additive manufacturing technologies is rapidly emerging as a disruptive approach for upgrading cancer-on-a-chip systems towards anatomic-sized dynamic in vitro models. This valuabl...
What can biofabrication do for space and what can space do for biofabrication? [0.03%]
生物打印能为太空探索做什么以及太空又能如何促进生物打印的发展？
Lorenzo Moroni,Kevin Tabury,Hilde Stenuit et al.
Lorenzo Moroni et al.
Biofabrication in space is one of the novel promising and prospective research directions in the rapidly emerging field of space STEM. There are several advantages of biofabrication in space. Under microgravity, it is possible to engineer c...
Progress and challenges in mass spectrometry-based analysis of antibody repertoires [0.03%]
基于质谱的抗体库分析中的进展与挑战
Igor Snapkov,Maria Chernigovskaya,Pavel Sinitcyn et al.
Igor Snapkov et al.
Humoral immunity is divided into the cellular B cell and protein-level antibody responses. High-throughput sequencing has advanced our understanding of both these fundamental aspects of B cell immunology as well as aspects pertaining to vac...
Munish Puri,Adarsha Gupta,Ross A McKinnon et al.
Munish Puri et al.
Microalgae have been evaluated as promising resource for biodiesel production, but algal biofuel production is not yet commercially viable, which reflects the high energy costs linked with cultivation, harvesting, and dewatering of algae. A...
Game-changing alternatives to conventional fungicides: small RNAs and short peptides [0.03%]
变革传统的杀菌剂：小RNA和短肽
Stefano Rosa,Paolo Pesaresi,Chiara Mizzotti et al.
Stefano Rosa et al.
Fungicide use is one of the core elements of intensive agriculture because it is necessary to fight pathogens that would otherwise cause large production losses. Oomycete and fungal pathogens are kept under control using several active comp...
Exploiting unconventional prokaryotic hosts for industrial biotechnology [0.03%]
利用非传统细菌宿主进行工业生物技术研究
Bastian Blombach,Alexander Grünberger,Florian Centler et al.
Bastian Blombach et al.
Developing cost-efficient biotechnological processes is a major challenge in replacing fossil-based industrial production processes. The remarkable progress in genetic engineering ensures efficient and fast tailoring of microbial metabolism...