Coexistence and collaboration: engineering encapsulation for whole-cell biosensors [0.03%]
共存与合作：工程封装整体细胞生物传感器技术
Zalike Keskin Erdogan,Kushaal Desai,Geoff S Baldwin et al.
Zalike Keskin Erdogan et al.
The emerging field of biosensors exploits the abilities of cells to identify specific molecules, presenting improved sensitivity, specificity, and limit of detection. Whole-cell biosensors (WCB) are organisms specifically engineered to dete...
Solar-driven PHB synthesis from wastewater by engineered semiconductor-bacteria biohybrids [0.03%]
工程半导体-细菌生物杂合体利用废水进行聚羟基链烷酸酯的太阳能合成
Fuliang Bai,Yuxin Wen,Shuo Liu et al.
Fuliang Bai et al.
Semiconductor biohybrid systems leverage microbial enzymatic precision and semiconductor light harvesting for efficient solar-to-chemical conversion, offering sustainable alternatives to energy-intensive production. To overcome challenges a...
Yan-Ruide Li,Yichen Zhu,Lili Yang
Yan-Ruide Li
In vivo chimeric antigen receptor (CAR) engineering has advanced into clinical trials with encouraging safety and efficacy. Technology breakthroughs, including targeted lipid nanoparticles, genetically modified lentiviruses, and optimized C...
Dual enhancement of mycoprotein nutrition and sustainability via CRISPR-mediated metabolic engineering of Fusarium venenatum [0.03%]
利用CRISPR介导的代谢工程同时增强卵菌营养和可持续性
Xiaohui Wu,Mengru Wang,Shijun Luo et al.
Xiaohui Wu et al.
Mycoprotein (MP) production represents a promising environmentally sustainable strategy to address global protein deficit. To enhance the nutritional profile and production efficiency of MP, we employed CRISPR/Cas9-mediated scarless gene kn...
Hengrui Zhou,Pingxin Lin,Ki Jun Jeong et al.
Hengrui Zhou et al.
Due to health and pollution concerns, sustainable textile production is receiving increasing attention. Bacterial cellulose (BC) offers an environmentally friendly alternative to petroleum-based fabrics. However, the use of petroleum-based ...
Advances in synthetic methanotrophy for sustainable C1 bioconversion [0.03%]
合成甲基营养菌的最新研究进展助力可持续的一碳生物转化技术发展
Claudia Tahiraj,Lucas Hille,Karen Brunsbach et al.
Claudia Tahiraj et al.
Methane (CH4) represents an abundant source of carbon and energy with significant potential for sustainable biotechnological processes. For efficient bioconversion of CH4 into value-added products, synthetic methanotrophy has emerged as a p...
Toward standardization of upscaled manufacturing of extracellular vesicles in hollow-fiber bioreactors [0.03%]
空纤维生物反应器中大规模制造外泌体的标准化研究进展
Paula Maria Pincela Lins,Daphne Lintsen,Sarah Willems et al.
Paula Maria Pincela Lins et al.
Dental pulp stem cells (DPSCs) reduce acute inflammation and induce angiogenesis, primarily through paracrine factors, in which extracellular vesicles (EVs) are pivotal. However, low production yields and poor standardization have hindered ...
Plant genome editing goes viral: balancing innovation and biosafety [0.03%]
植物基因组编辑进入病毒时代：创新与生物安全并行不悖
Koppolu Raja Rajesh Kumar
Koppolu Raja Rajesh Kumar
Weiss and colleagues demonstrated a breakthrough in transgene-free heritable genome editing using viral vectors. While promising for controlled laboratory applications, the open-field use envisaged by Sajjad and colleagues raises ecological...
Reem Yasser,Mingrui Yu,Nianchao Qian et al.
Reem Yasser et al.
Spatial omics maps cell types and spatial context together. Current methods fall into two streams: mapping coordinates (where things are) and measuring connections between cells that are in contact or close proximity. We introduce the term ...
Recycling CO2 into bioingredients: towards synthetic photo/litho-mixotrophy [0.03%]
二氧化碳循环利用生成生物基原料——合成光电/光矿混营养体的构建初探
Bingyin Peng,Huadong Peng,Robert E Speight
Bingyin Peng
Advances in carbon capture and gas fermentation technologies enable the sustainable production of one-carbon (C1) and C2 organic molecules, such as formate and acetate, by recycling CO2 and organic wastes. Refining C1 and C2 feedstocks into...