Inês Soares Marques,Raquel Almeida,Pedro F Costa
Inês Soares Marques
Cancer-associated thrombosis (CAT) is the second leading cause of death among cancer patients, driven by tumour-haemostasis interactions. While traditional models have proven invaluable to study this process, they often fail to replicate it...
Xianhao Xu,Yang Li,Jiaheng Liu et al.
Xianhao Xu et al.
Recent advances in post-translational regulatory tools have enabled precise and rapid control of metabolic flux in microbial cell factories. In this review, we systematically summarize current post-translational regulatory tools for modulat...
Towards biocatalytic conversion driven by (photo)electrocatalytic cofactor regeneration [0.03%]
基于(光)电催化辅因子再生的生物转化研究进展
Guanhua Liu,Yanjun Jiang
Guanhua Liu
In a recent study, Bachar et al. developed an enzymatic biocathode-based bioelectrocatalytic platform for efficient synthesis of chiral compounds. They then integrated this system with a semiconductor-based photoanode to construct a light-d...
Helen Crooke,Stefanie Schwindt,Sarah L Fletcher et al.
Helen Crooke et al.
Infectious diseases remain a major impediment to livestock production, negatively impacting both productivity and welfare. Where key interactions between viruses and host proteins have been identified, it is possible to rationally devise in...
Lucas D van der Zee,Niels R Peeters,Marcel C G Proveniers et al.
Lucas D van der Zee et al.
Dominant forms of agriculture burden our environment, and food production is threatened by climate change. In this opinion article we introduce a paradigm shift in food production by describing a method to cultivate fruit without having to ...
Jasdeep S Ghataora,Tom Ellis
Jasdeep S Ghataora
Holobionts are complex communities comprising a host and its diverse microbiota. Their intricate relationships are crucial for biological processes like nutrient uptake, immune function, and environmental adaptation. However, understanding ...
Siqi Wang,Wei Li,Guihai Feng
Siqi Wang
Functional de-extinction is the process of creating organisms with traits resembling those of extinct species that benefit modern ecosystems. Advances in genome-wide sequencing, gene editing and traditional cloning technologies have substan...
Chloroplast engineering for enhancing photosynthetic efficiency and agronomic traits [0.03%]
叶绿体工程在提高光合作用效率和农艺性状中的应用
Srishti Jaswal,Ashish K Srivastava,Anand Ballal et al.
Srishti Jaswal et al.
Plant chloroplast, the vital organelle that performs photosynthesis, is essential for sustaining life on Earth. It not only converts light energy into food while releasing O2 in the process, but also consumes CO2, thereby reducing the pace ...
A reversible genetic NOR gate in plants using translational repression [0.03%]
利用翻译抑制在植物中构建可逆的遗传NOR门
Aakash Jog,Ron Sverdlov,Silvia Schuster et al.
Aakash Jog et al.
A proof-of-concept reversible genetic logic circuit in tobacco plants is presented. The genetic circuit implements a Boolean NOR function using a Cas6-based translational repression system, with exposure to estradiol and ethanol as inputs, ...
Alex B Lu,Anna C F Lewis
Alex B Lu
A common framing for governing artificial intelligence (AI) in the biological sciences is to focus on risk mitigation owing to the technology's potential 'dual-use' for both beneficial and harmful applications. This is a reactive policy app...