Linjie Zhou,Biao Li,Jianhua Guo et al.
Linjie Zhou et al.
Nitrate in groundwater should be treated as a nitrogen source rather than a contaminant. Biohybrid technologies coupling microbial selectivity with renewable electro(photo)chemical energy offer opportunities to convert nitrate to value-adde...
Engineering environmental bacteria for whole-cell PET hydrolysis and assimilation [0.03%]
工程化环境细菌进行全细胞PET水解和同化
Alice M Banks,Umar Abdulmutalib,Brooke Wain et al.
Alice M Banks et al.
Poly(ethylene terephthalate) (PET) is one of the most widely used plastics in food and textile applications, yet post-consumer PET waste persists and accumulates in the environment as macro- and microplastics with adverse health and ecologi...
Acoustic cavitation-enhanced lymphatic trafficking of inhaled bacterial-sourced biohybrid vaccines for antitumor immunity [0.03%]
声空化增强的吸入细菌源生物杂合疫苗的淋巴转运以对抗肿瘤免疫
Jingben Zheng,Yu Zhang,Xiaoye Li et al.
Jingben Zheng et al.
The clinical translation of personalized cancer vaccines is currently impeded by the dual challenges of rapid antigen manufacturing and inefficient delivery to lymphoid tissues. In this study, we present a biohybrid nanovaccine platform tha...
Junhua Guo,Jinpeng Wang,Yuxiang Hong et al.
Junhua Guo et al.
Metabolic engineering efforts are determined not only by enzyme activity but also by the thermodynamic driving force. This forum argues that many 'novel' synthetic routes merely relocate energetic penalties rather than eliminate them and de...
Engineering a capture-bioremediate-release microbial biofilm for simultaneous bioremediation of microplastics and adsorbed heavy metals [0.03%]
工程设计捕获-生物修复-释放微生物菌落以同时进行微塑料和吸附重金属的生物修复
Wei Wei,Song Lin Chua
Wei Wei
Microplastics (MPs) pose escalating environmental and human health risks, particularly when they adsorb heavy metals and form complex, co-contaminated pollutants. Furthermore, when MPs are removed and sent to landfills or incineration, the ...
Nona Hashemi,Karen O Osiro,Octavio L Franco et al.
Nona Hashemi et al.
Bacterial systems are emerging as living technologies for sustainable manufacturing, environmental monitoring, agriculture, and health. They form biofilms, that is, living materials, which can be repurposed in biological applications due to...
Multiscale and programmable engineering of edible mushroom mycelium-based materials [0.03%]
基于食用蘑菇菌丝的多尺度和可编程工程材料
Xiangfen Kong,Shijun Xiao,Hongwen Yu et al.
Xiangfen Kong et al.
Edible mushroom mycelium-based materials are emerging as renewable, route-dependent systems spanning composites, flexible sheets, hydrogels, aerogels, and hybrid materials, rather than a single engineering class. In this review, we synthesi...
Yajie Cheng,Xiuchao Xie,Liang Guo et al.
Yajie Cheng et al.
Microbial cell factories are central platforms for sustainable industrial biomanufacturing, yet inefficient transmembrane transport continues to hinder their large-scale industrial translation. Transporter engineering has progressed from tr...
Random integration and high-throughput screening forging robust microbial cell factories [0.03%]
随机整合和高通量筛选锻造稳健的微生物细胞工厂
Jiangnan Hua,Pengxiang Song,Jing Wu et al.
Jiangnan Hua et al.
Microbial cell factories are central to sustainable biomanufacturing. This Forum article discusses how random integration, coupled with high-throughput screening (HTS) and AI, enables the mapping of favorable genomic loci to guide targeted ...
Reprogrammable bacterial nanosyringes to deliver RNA and gene editors [0.03%]
可重新编程的细菌纳米注射器用于递送RNA和基因编辑工具
Haishan Xu,Lei Feng,Ningning Song et al.
Haishan Xu et al.
The engineered Photorhabdus virulence cassette (PVC) enables precise protein delivery but has not yet achieved RNA packaging and injection delivery. In this study, we achieved intraluminal RNA loading via the U1A RNA-binding domain, anchori...