Haotian Yu,Zuhong Lu,Dachao Li et al.
Haotian Yu et al.
DNA has emerged as a promising medium for next-generation information storage due to its ultra-high storage density, long-term stability, and low energy consumption. With the rapid growth of global digital data, DNA storage provides a poten...
Repurposing CRISPR-associated transposases for engineering microbiology [0.03%]
用于工程微生物学的CRISPR相关转座酶的新用途
Tao Chang,Bo Xin,Jinshan Li et al.
Tao Chang et al.
Clustered regularly interspaced short palindromic repeats (CRISPR) systems have revolutionized microbial genome editing. However, their reliance on DNA double-strand breaks (DSBs) and homologous recombination limits applications such as lar...
Marine discovery, nonmarine deployment: A translation paradox in blue biotechnology [0.03%]
从海洋发现到陆地应用：蓝色生物技术中的一个翻译悖论
Marco F L Lemos
Marco F L Lemos
Marine biotechnology draws on one of the richest sources of biological novelty on Earth. Yet, as investment accelerates alongside new international ocean governance frameworks, marine discoveries rarely reach the market as marine production...
Lei Zhou,Hong Chen,Yonghong Wu et al.
Lei Zhou et al.
Industrial systems contribute approximately 30% of total anthropogenic CO2 emissions. Microalgal-based CO2 capture from industrial off-gases is a promising self-sustainable technology, but its efficacy is limited by the toxicity of high CO2...
CRISPR/Cas14a-based logic system for intelligent microplastic monitoring based on multiple DNA walking mechanisms [0.03%]
基于多重DNA行走机制的智能微塑料监测的CRISPR/Cas14a逻辑系统
Xiaoya Ren,Xu Cui,Ying Zeng et al.
Xiaoya Ren et al.
In this research article, an intelligent clustered regularly interspaced short palindromic repeats (CRISPR)/Cas14a-based logic system was developed for microplastic monitoring on the basis of catalytic hairpin assembly (CHA) and DNA walkers...
Smart biomaterials: From responsiveness to closed-loop sensing and feedback [0.03%]
智能生物材料：从响应性到闭环感应和反馈
Masoud Mozafari,Tatjana Ivaskiene,Greta Kaspute et al.
Masoud Mozafari et al.
Biomaterials are evolving from passive scaffolds to responsive platforms, yet most lack true feedback regulation. A shift toward adaptive biomaterial systems that integrate sensing, computational processing, and dynamic actuation directly w...
Bacterial spores as a modular platform for the production of amyloids for materials [0.03%]
芽孢作为生产淀粉样蛋白材料的模块化平台
Carina Dietz,Maren Kvilten,Simona Sebastiano et al.
Carina Dietz et al.
We present a proof-of-concept platform in which amyloids are displayed on the surface of engineered Bacillus subtilis spores for bioengineered materials. Amyloids possess high tensile strength, elasticity, and tunable assembly, but their us...
The oriGen case and Mexico's regulatory blind spots in genomic biobanking [0.03%]
オリジン案列及墨西哥基因组生物库监管盲点问题
Guillermo Aquino-Jarquin
Guillermo Aquino-Jarquin
The oriGen project represents a pioneering but institutionally anchored response to Mexico's regulatory gap. Yet, viewed through the lens of contemporary scholarship, its model-private university ownership, broad individual consent, and ext...
A caspase-3-activated protein expression system for apoptosis visualization and apoptosis-pyroptosis conversion to boost antitumor activity [0.03%]
一种用于凋亡可视化和凋亡-焦亡转换增强抗肿瘤活性的caspase-3激活蛋白表达系统
Wen-Jie Shu,Chunxia He,Zhe Ma et al.
Wen-Jie Shu et al.
Dysregulation of cell death is a hallmark of cancer, and overcoming tumor resistance to apoptosis-inducing therapies remains challenging. Inducing immunogenic cell death (ICD), such as pyroptosis, is promising but currently lacks tools for ...
Over 4 months of ethylene production using solid-state photosynthetic cell factories [0.03%]
固体状态光合成细胞工厂的四个月乙烯生产试验
Sergey N Kosourov,Vilja Siitonen,Gábor S Tóth et al.
Sergey N Kosourov et al.
This study demonstrates the feasibility of solid-state photosynthetic cell factories for long-term ethylene production. Engineered Synechocystis sp. PCC 6803 expressing the ethylene-forming enzyme was immobilized in 2,2,6,6-tetramethylpiper...